TNSN08196A1 - Derives de pyrazine - Google Patents
Derives de pyrazineInfo
- Publication number
- TNSN08196A1 TNSN08196A1 TNP2008000196A TNSN08196A TNSN08196A1 TN SN08196 A1 TNSN08196 A1 TN SN08196A1 TN P2008000196 A TNP2008000196 A TN P2008000196A TN SN08196 A TNSN08196 A TN SN08196A TN SN08196 A1 TNSN08196 A1 TN SN08196A1
- Authority
- TN
- Tunisia
- Prior art keywords
- des
- composés
- préparer
- pour les
- les
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
La présente invention concerne des composés de formule (I), des sels et solvates de ceux-ci, acceptables d'un point de vue pharmaceutique, des procédés pour les préparer, des produits intermédiaires utilisés pour les préparer, des compositions contenant ces composés, ainsi que les utilisations de tels composés dans le traitement de la douleur.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73366205P | 2005-11-04 | 2005-11-04 | |
PCT/IB2006/003055 WO2007052123A2 (fr) | 2005-11-04 | 2006-10-23 | Derives de pyrazine |
Publications (1)
Publication Number | Publication Date |
---|---|
TNSN08196A1 true TNSN08196A1 (fr) | 2009-10-30 |
Family
ID=37890558
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNP2008000196A TNSN08196A1 (fr) | 2005-11-04 | 2008-05-02 | Derives de pyrazine |
Country Status (27)
Country | Link |
---|---|
US (1) | US7572797B2 (fr) |
EP (1) | EP1945630B1 (fr) |
JP (1) | JP2009514937A (fr) |
KR (1) | KR20080066073A (fr) |
CN (1) | CN101356169A (fr) |
AP (1) | AP2008004468A0 (fr) |
AR (1) | AR057855A1 (fr) |
AT (1) | ATE525372T1 (fr) |
AU (1) | AU2006310215A1 (fr) |
BR (1) | BRPI0618129A2 (fr) |
CA (1) | CA2624621C (fr) |
CR (1) | CR9954A (fr) |
DO (1) | DOP2006000243A (fr) |
EA (1) | EA200801011A1 (fr) |
EC (1) | ECSP088412A (fr) |
ES (1) | ES2371932T3 (fr) |
GT (1) | GT200600475A (fr) |
IL (1) | IL191059A0 (fr) |
MA (1) | MA29926B1 (fr) |
NL (1) | NL2000284C2 (fr) |
NO (1) | NO20082496L (fr) |
PE (1) | PE20070715A1 (fr) |
TN (1) | TNSN08196A1 (fr) |
TW (1) | TW200804353A (fr) |
UY (1) | UY29893A1 (fr) |
WO (1) | WO2007052123A2 (fr) |
ZA (1) | ZA200803671B (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6001876A (en) | 1996-07-24 | 1999-12-14 | Warner-Lambert Company | Isobutylgaba and its derivatives for the treatment of pain |
EP1741708A1 (fr) * | 2005-06-28 | 2007-01-10 | Sanofi-Aventis Deutschland GmbH | Amides heterocycliques substitués contenant un linker cyclique ou insaturé, et leur utilisation comme agent pharmaceutique |
US8399666B2 (en) | 2005-11-04 | 2013-03-19 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
US7977359B2 (en) | 2005-11-04 | 2011-07-12 | Amira Pharmaceuticals, Inc. | 5-lipdxygenase-activating protein (FLAP) inhibitors |
GB2431927B (en) | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
US20100227872A1 (en) * | 2007-05-03 | 2010-09-09 | Mark Ian Kemp | Pyrazine derivatives |
ES2398606T3 (es) | 2007-05-03 | 2013-03-20 | Pfizer Limited | Derivados de 2-piridin-carboxamida como moduladores de los canales de sodio |
US8614255B2 (en) * | 2007-08-21 | 2013-12-24 | Civitas Therapeutics, Inc. | Pulmonary pharmaceutical formulations |
AU2008334629B2 (en) | 2007-12-10 | 2012-04-12 | Novartis Ag | Organic compounds |
RU2010137862A (ru) | 2008-02-13 | 2012-03-20 | ЭЙСАЙ Ар энд Ди МЕНЕДЖМЕНТ КО., ЛТД. (JP) | Производное бициклоамина |
EA019819B1 (ru) | 2008-05-23 | 2014-06-30 | ПАНМИРА ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Кристаллическая полиморфная форма с ингибитора белка, активирующего 5-липоксигеназу, фармацевтическая композиция на ее основе и применение в лечении |
US8546431B2 (en) | 2008-10-01 | 2013-10-01 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
US10703722B2 (en) | 2010-04-27 | 2020-07-07 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
US9856240B2 (en) * | 2011-10-19 | 2018-01-02 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
TWI577677B (zh) * | 2012-04-25 | 2017-04-11 | 拉夸里亞創藥股份有限公司 | 作爲ttx-s阻斷劑之吡咯並吡啶酮衍生物 |
TWI644899B (zh) * | 2013-02-04 | 2018-12-21 | 健生藥品公司 | Flap調節劑 |
US9079866B2 (en) | 2013-02-04 | 2015-07-14 | Janssen Pharmaceutica Nv | Flap modulators |
EP3193603A4 (fr) * | 2014-09-10 | 2018-02-28 | Epizyme, Inc. | Composés carboxamides isoxazoles |
US11311535B2 (en) | 2015-02-27 | 2022-04-26 | Calcimedica, Inc. | Pancreatitis treatment |
CA2995094A1 (fr) * | 2015-08-07 | 2017-02-16 | Calcimedica, Inc. | Utilisation d'inhibiteurs du canal crac pour le traitement d'un accident vasculaire cerebral et d'une lesion cerebrale traumatique |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA26473A1 (fr) * | 1997-03-01 | 2004-12-20 | Glaxo Group Ltd | Composes pharmacologiquement actifs. |
CA2467870A1 (fr) * | 2001-11-21 | 2003-06-05 | Pharmacia & Upjohn Company | Derives d'aryle-1,4-pyrazine substitues |
US20030187026A1 (en) | 2001-12-13 | 2003-10-02 | Qun Li | Kinase inhibitors |
WO2005040151A1 (fr) * | 2003-10-27 | 2005-05-06 | Astellas Pharma Inc. | Derives de pyrazine et utilisation pharmaceutique de ce derive |
WO2006047504A1 (fr) * | 2004-10-22 | 2006-05-04 | Janssen Pharmaceutica, N.V. | Amides aromatiques en tant qu’inhibiteurs de kinase c-fms |
-
2006
- 2006-10-20 NL NL2000284A patent/NL2000284C2/nl not_active IP Right Cessation
- 2006-10-23 JP JP2008539517A patent/JP2009514937A/ja not_active Ceased
- 2006-10-23 KR KR1020087013403A patent/KR20080066073A/ko not_active Application Discontinuation
- 2006-10-23 AP AP2008004468A patent/AP2008004468A0/xx unknown
- 2006-10-23 WO PCT/IB2006/003055 patent/WO2007052123A2/fr active Search and Examination
- 2006-10-23 EA EA200801011A patent/EA200801011A1/ru unknown
- 2006-10-23 BR BRPI0618129-5A patent/BRPI0618129A2/pt not_active IP Right Cessation
- 2006-10-23 AT AT06809149T patent/ATE525372T1/de not_active IP Right Cessation
- 2006-10-23 EP EP06809149A patent/EP1945630B1/fr not_active Not-in-force
- 2006-10-23 CN CNA2006800504914A patent/CN101356169A/zh active Pending
- 2006-10-23 CA CA2624621A patent/CA2624621C/fr not_active Expired - Fee Related
- 2006-10-23 AU AU2006310215A patent/AU2006310215A1/en not_active Abandoned
- 2006-10-23 ES ES06809149T patent/ES2371932T3/es active Active
- 2006-11-01 UY UY29893A patent/UY29893A1/es not_active Application Discontinuation
- 2006-11-02 GT GT200600475A patent/GT200600475A/es unknown
- 2006-11-02 AR ARP060104815A patent/AR057855A1/es unknown
- 2006-11-03 DO DO2006000243A patent/DOP2006000243A/es unknown
- 2006-11-03 US US11/556,354 patent/US7572797B2/en not_active Expired - Fee Related
- 2006-11-03 TW TW095140879A patent/TW200804353A/zh unknown
- 2006-11-03 PE PE2006001349A patent/PE20070715A1/es not_active Application Discontinuation
-
2008
- 2008-04-25 ZA ZA200803671A patent/ZA200803671B/xx unknown
- 2008-04-27 IL IL191059A patent/IL191059A0/en unknown
- 2008-04-29 EC EC2008008412A patent/ECSP088412A/es unknown
- 2008-05-02 TN TNP2008000196A patent/TNSN08196A1/fr unknown
- 2008-05-02 MA MA30893A patent/MA29926B1/fr unknown
- 2008-05-07 CR CR9954A patent/CR9954A/es not_active Application Discontinuation
- 2008-06-04 NO NO20082496A patent/NO20082496L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2624621C (fr) | 2010-11-30 |
ATE525372T1 (de) | 2011-10-15 |
KR20080066073A (ko) | 2008-07-15 |
AP2008004468A0 (en) | 2008-06-30 |
US20070105872A1 (en) | 2007-05-10 |
DOP2006000243A (es) | 2007-05-31 |
ZA200803671B (en) | 2009-03-25 |
GT200600475A (es) | 2007-07-06 |
CN101356169A (zh) | 2009-01-28 |
BRPI0618129A2 (pt) | 2011-08-16 |
IL191059A0 (en) | 2008-12-29 |
ECSP088412A (es) | 2008-05-30 |
NO20082496L (no) | 2008-07-24 |
UY29893A1 (es) | 2007-06-29 |
WO2007052123A2 (fr) | 2007-05-10 |
MA29926B1 (fr) | 2008-11-03 |
PE20070715A1 (es) | 2007-08-11 |
CA2624621A1 (fr) | 2007-05-10 |
TW200804353A (en) | 2008-01-16 |
WO2007052123A3 (fr) | 2007-07-12 |
EP1945630B1 (fr) | 2011-09-21 |
EP1945630A2 (fr) | 2008-07-23 |
US7572797B2 (en) | 2009-08-11 |
AR057855A1 (es) | 2007-12-19 |
CR9954A (es) | 2008-05-28 |
EA200801011A1 (ru) | 2009-02-27 |
NL2000284A1 (nl) | 2007-05-07 |
AU2006310215A1 (en) | 2007-05-10 |
NL2000284C2 (nl) | 2007-09-28 |
ES2371932T3 (es) | 2012-01-11 |
JP2009514937A (ja) | 2009-04-09 |
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