TNSN07482A1 - Nouvelles compositions injectables et procede de preparation desdites compositions - Google Patents

Nouvelles compositions injectables et procede de preparation desdites compositions

Info

Publication number
TNSN07482A1
TNSN07482A1 TNP2007000482A TNSN07482A TNSN07482A1 TN SN07482 A1 TNSN07482 A1 TN SN07482A1 TN P2007000482 A TNP2007000482 A TN P2007000482A TN SN07482 A TNSN07482 A TN SN07482A TN SN07482 A1 TNSN07482 A1 TN SN07482A1
Authority
TN
Tunisia
Prior art keywords
pain
compositions
conditions
inflammatory
cox
Prior art date
Application number
TNP2007000482A
Other languages
English (en)
Inventor
Rajesh Jain
Kour Chand Jindal
Sukhjeet Singh
Sanjay Boldhane
Original Assignee
Panacea Biotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panacea Biotec Ltd filed Critical Panacea Biotec Ltd
Publication of TNSN07482A1 publication Critical patent/TNSN07482A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des compositions pharmaceutiques injectables, nouvelles et hautement stables, qui comprennent au moins un inhibiteur de la cyclooxygénase-II (COX-II) ou un anti-inflammatoire non stéroïdien (AINS) ou un inhibiteur de COX/LOX ou leurs formes tautomères, analogues, isomères, polymorphes, solvates, promédicaments ou sels de ces derniers comme principe actif approprié à une administration parentérale, de préférence, par voie intramusculaire (IM) ou intraveineuse (IV). L'invention concerne également un procédé de préparation de ces compositions et des méthodes thérapeutiques d'utilisation de ces compositions. Les compositions injectables analgésiques et anti-inflammatoires selon l'invention sont très utiles chez les mammifères, notamment les humains, pour le traitement d'états douloureux aigus tels qu'un ou plusieurs des états suivants : traumatismes postopératoires, douleur associée au cancer, blessures de sport, migraine, douleur neurologique et douleur associée à la sciatique et à la spondylarthrite et à des maladies analogues et/ou des états de douleur chronique et/ou divers états inflammatoires douloureux, tels que la douleur postopératoire, la dysménorrhée primaire et l'arthrose douloureuse, et/ou d'autres troubles associés, tels que l'inflammation, la fièvre, l'allergie ou des états analogues.
TNP2007000482A 2005-05-27 2007-12-21 Nouvelles compositions injectables et procede de preparation desdites compositions TNSN07482A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1357DE2005 2005-05-27
PCT/IN2006/000177 WO2006126214A2 (fr) 2005-05-27 2006-05-25 Nouvelles compositions injectables et procede de preparation desdites compositions

Publications (1)

Publication Number Publication Date
TNSN07482A1 true TNSN07482A1 (fr) 2009-03-17

Family

ID=36917368

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2007000482A TNSN07482A1 (fr) 2005-05-27 2007-12-21 Nouvelles compositions injectables et procede de preparation desdites compositions

Country Status (15)

Country Link
EP (1) EP1895983A2 (fr)
JP (1) JP2008542260A (fr)
KR (1) KR20080016689A (fr)
CN (1) CN101217939A (fr)
AU (1) AU2006250765A1 (fr)
BR (1) BRPI0611170A2 (fr)
CA (1) CA2609242A1 (fr)
CR (1) CR9616A (fr)
EA (1) EA200702646A1 (fr)
MX (1) MX2007014862A (fr)
NO (1) NO20076468L (fr)
RS (1) RS20070461A (fr)
TN (1) TNSN07482A1 (fr)
WO (1) WO2006126214A2 (fr)
ZA (1) ZA200711068B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103181893A (zh) 2007-09-07 2013-07-03 联合治疗公司 针对革兰氏阴性细菌具有选择性杀菌活性的缓冲液及其使用方法
ES2823249T3 (es) 2009-03-12 2021-05-06 Cumberland Pharmaceuticals Inc Administración de ibuprofeno por vía intravenosa
US8871810B2 (en) 2009-07-15 2014-10-28 Cumberland Pharmaceuticals Inc. Treating critically ill patients with intravenous ibuprofen
CN102335114B (zh) * 2010-07-23 2015-07-15 重庆医药工业研究院有限责任公司 一种稳定的布洛芬精氨酸注射剂及其制备方法
CN102370615B (zh) * 2010-08-19 2013-09-04 四川科伦药物研究有限公司 一种布洛芬注射制剂及其制备方法
ES2859676T3 (es) 2011-10-18 2021-10-04 Askat Inc Composición medicinal
CN102512383A (zh) * 2011-12-25 2012-06-27 天津市嵩锐医药科技有限公司 供注射用的帕瑞昔布钠药物组合物
US9072710B2 (en) 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
CN103372216B (zh) * 2012-04-26 2015-05-06 北京京卫燕康药物研究所有限公司 一种含有塞来昔布的固体药物组合物
TWI646091B (zh) 2012-12-28 2019-01-01 日商衛斯克慧特股份有限公司 鹽類及晶形
US20140187635A1 (en) 2012-12-28 2014-07-03 Themis Medicare Limited Diclofenac compositions
US20140275261A1 (en) 2013-03-15 2014-09-18 Dr. Reddy's Laboratories, Inc. Diclofenac parenteral compositions
CN103263385B (zh) * 2013-05-17 2016-04-27 江苏正大清江制药有限公司 一种塞来昔布长效纳米注射剂及其制备方法
PE20171305A1 (es) * 2014-12-20 2017-09-05 Troikaa Pharmaceuticals Ltd Formulaciones inyectables de paracetamol
WO2016170401A1 (fr) * 2015-04-20 2016-10-27 Umedica Laboratories Pvt. Ltd Nouvelle composition injectable de diclofénac sodique
CN107303266B (zh) * 2016-04-18 2020-09-08 重庆润泽医药有限公司 左旋奥拉西坦注射液及其制备方法
CN107303264A (zh) * 2016-04-18 2017-10-31 重庆润泽医药有限公司 无泡沫左旋奥拉西坦注射液及其制备方法
FR3077984B1 (fr) * 2018-02-16 2020-02-21 Vetoquinol Sa Composition multiusage de torasemide
CN109498852B (zh) * 2018-12-29 2022-06-24 广州噢斯荣医药技术有限公司 治疗骨科疾病的生物降解材料及其应用
CN111103381A (zh) * 2019-12-25 2020-05-05 南京希麦迪医药科技有限公司 一种液质联用测定人血浆中尼美舒利浓度的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5389681A (en) * 1992-10-22 1995-02-14 Ciba-Geigy Corporation Parenteral solutions for diclofenac salts
IT1283252B1 (it) * 1996-03-15 1998-04-16 Pulitzer Italiana Soluzioni di piroxicam iniettabili per via parenterale
IN187306B (fr) * 1998-01-12 2002-03-23 Panacea Biotec Ltd
US7695736B2 (en) * 2001-04-03 2010-04-13 Pfizer Inc. Reconstitutable parenteral composition
AU2003249510A1 (en) * 2002-08-12 2004-02-25 Ranbaxy Laboratories Limited A parenteral dosage form of selective cox-2 inhibitors

Also Published As

Publication number Publication date
NO20076468L (no) 2008-02-27
MX2007014862A (es) 2008-02-21
WO2006126214A3 (fr) 2007-06-07
RS20070461A (en) 2008-11-28
EA200702646A1 (ru) 2008-06-30
AU2006250765A1 (en) 2006-11-30
WO2006126214A2 (fr) 2006-11-30
CN101217939A (zh) 2008-07-09
KR20080016689A (ko) 2008-02-21
JP2008542260A (ja) 2008-11-27
CA2609242A1 (fr) 2006-11-30
ZA200711068B (en) 2009-03-25
BRPI0611170A2 (pt) 2010-08-17
CR9616A (es) 2008-10-30
EP1895983A2 (fr) 2008-03-12

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