DE60110185D1 - Zusammensetzung und Verfahren zur parenteralen Anwendung von Ibuprofen-D,L-, oder L-Lysinat - Google Patents

Zusammensetzung und Verfahren zur parenteralen Anwendung von Ibuprofen-D,L-, oder L-Lysinat

Info

Publication number
DE60110185D1
DE60110185D1 DE60110185T DE60110185T DE60110185D1 DE 60110185 D1 DE60110185 D1 DE 60110185D1 DE 60110185 T DE60110185 T DE 60110185T DE 60110185 T DE60110185 T DE 60110185T DE 60110185 D1 DE60110185 D1 DE 60110185D1
Authority
DE
Germany
Prior art keywords
ibuprofen
parenteral administration
absence
active ingredient
inert atmosphere
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60110185T
Other languages
English (en)
Other versions
DE60110185T2 (de
Inventor
Laszlo Darko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Farmacon Il LLC
Original Assignee
Farmacon Il LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmacon Il LLC filed Critical Farmacon Il LLC
Publication of DE60110185D1 publication Critical patent/DE60110185D1/de
Application granted granted Critical
Publication of DE60110185T2 publication Critical patent/DE60110185T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE60110185T 2000-11-14 2001-11-08 Zusammensetzung und Verfahren zur parenteralen Anwendung von Ibuprofen-D,L-, oder L-Lysinat Expired - Lifetime DE60110185T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/712,430 US6342530B1 (en) 2000-11-14 2000-11-14 Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt
US712430 2000-11-14

Publications (2)

Publication Number Publication Date
DE60110185D1 true DE60110185D1 (de) 2005-05-25
DE60110185T2 DE60110185T2 (de) 2006-03-09

Family

ID=24862079

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60110185T Expired - Lifetime DE60110185T2 (de) 2000-11-14 2001-11-08 Zusammensetzung und Verfahren zur parenteralen Anwendung von Ibuprofen-D,L-, oder L-Lysinat

Country Status (7)

Country Link
US (1) US6342530B1 (de)
EP (1) EP1205181B9 (de)
JP (1) JP2002193799A (de)
AT (1) ATE293444T1 (de)
CA (1) CA2361160A1 (de)
DE (1) DE60110185T2 (de)
MX (1) MXPA01011629A (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
WO2004037242A1 (en) * 2002-10-25 2004-05-06 Dompe S.P.A. Painless injectable compositions containing salt of 2-arylpropionic acids
US6753350B1 (en) 2003-03-24 2004-06-22 Bristol-Myers Squibb Company Method to reduce the incidence of intraventricular hemorrhage in preterm infants
US20050176809A1 (en) * 2004-02-05 2005-08-11 Rodlen Laboratories, Inc. Method and compositions for treatment of painful disorders
AU2007267612A1 (en) * 2006-05-26 2007-12-06 Auspex Pharmaceuticals, Inc. Preparation and utility of substituted carboxylic acid compounds
ES2405733T3 (es) * 2006-07-26 2013-06-03 The Board Of Regents Of The University Of Texas System Preparaciones parenterales de antiinflamatorios asociados a fosfolípidos GI más seguros y procedimientos de preparación y uso
KR20140014350A (ko) * 2009-03-12 2014-02-06 큠버랜드 파마슈티컬즈 인코포레이티드 정맥 내 투여용 이부프로펜의 투여
US8735452B2 (en) * 2009-07-15 2014-05-27 Cumberland Pharmaceuticals Inc. Treating patients with intravenous ibuprofen
US8871810B2 (en) * 2009-07-15 2014-10-28 Cumberland Pharmaceuticals Inc. Treating critically ill patients with intravenous ibuprofen
WO2011014208A1 (en) * 2009-07-31 2011-02-03 Leo Pavliv Treating critically ill patients with intravenous ibuprofen
US8415337B1 (en) 2011-03-06 2013-04-09 Recordati Rare Diseases Inc. Ibuprofen compositions and methods of making same
ES2422563B1 (es) * 2012-03-08 2014-06-10 Farmalider S.A. Composición farmacéutica inyectable de ibuprofeno y arginina, su procedimiento de preparación, forma de dosificación unitaria y utilización de la misma
US9072661B2 (en) 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
US9072710B2 (en) 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
GR1008942B (el) * 2015-10-14 2017-02-06 ΙΟΥΛΙΑ ΚΑΙ ΕΙΡΗΝΗ ΤΣΕΤΗ ΦΑΡΜΑΚΕΥΤΙΚΑ ΕΡΓΑΣΤΗΡΙΑ ΑΒΕΕ με δ.τ. "INTERMED ΑΒΕΕ" Μεθοδος παραγωγης σταθερου υδατικου διαλυματος λυσινικης ιμπουπροφαινης για ενδοκολπικη χρηση
KR101924786B1 (ko) 2017-07-31 2018-12-04 주식회사 인트로바이오파마 이부프로펜의 주사용 약제학적 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1497044A (en) 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
DE3301328A1 (de) * 1982-02-01 1983-08-11 The Upjohn Co., 49001 Kalamazoo, Mich. Arzneimittel zur einleitenden bekaempfung von akuter oder chronischer, myelogener leukaemie
DE3328401A1 (de) 1983-08-05 1985-02-21 Merckle GmbH, 7902 Blaubeuren Injizierbare loesung zur behandlung von entzuendungen
JPH0647532B2 (ja) * 1983-08-31 1994-06-22 ジ アツプジヨン カンパニ− 歯槽骨吸収の治療
US4994604A (en) 1990-01-10 1991-02-19 Merck & Co., Inc. Formation and resolution of ibuprofen lysinate
ES2093192T3 (es) 1991-03-22 1996-12-16 Merck & Co Inc Formulacion farmaceutica con elevado contenido de lisinato de ibuprofeno.
US5472954A (en) * 1992-07-14 1995-12-05 Cyclops H.F. Cyclodextrin complexation
IT1264855B1 (it) 1993-06-21 1996-10-17 Zambon Spa Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici
IT1277741B1 (it) 1995-12-28 1997-11-12 Dompe Spa Composizioni farmaceutiche parenterali contenenti sali di alchilammonio di acidi 2-arilpropionici

Also Published As

Publication number Publication date
EP1205181B9 (de) 2005-07-27
EP1205181A3 (de) 2002-08-21
US6342530B1 (en) 2002-01-29
CA2361160A1 (en) 2002-05-14
EP1205181A2 (de) 2002-05-15
EP1205181B1 (de) 2005-04-20
MXPA01011629A (es) 2005-10-19
JP2002193799A (ja) 2002-07-10
DE60110185T2 (de) 2006-03-09
ATE293444T1 (de) 2005-05-15

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Legal Events

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8328 Change in the person/name/address of the agent

Representative=s name: DF-MP, 80333 MUENCHEN