DE602004020494D1 - Analgetische verbindungen, deren synthese und pharmazeutische zusammensetzungen, die diese enthalten - Google Patents
Analgetische verbindungen, deren synthese und pharmazeutische zusammensetzungen, die diese enthaltenInfo
- Publication number
- DE602004020494D1 DE602004020494D1 DE602004020494T DE602004020494T DE602004020494D1 DE 602004020494 D1 DE602004020494 D1 DE 602004020494D1 DE 602004020494 T DE602004020494 T DE 602004020494T DE 602004020494 T DE602004020494 T DE 602004020494T DE 602004020494 D1 DE602004020494 D1 DE 602004020494D1
- Authority
- DE
- Germany
- Prior art keywords
- synthesis
- pharmaceutical compositions
- compositions containing
- compounds
- analgetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/682,744 US6806291B1 (en) | 2003-10-09 | 2003-10-09 | Analgesic compounds, their synthesis and pharmaceutical compositions containing them |
PCT/US2004/033609 WO2005035485A2 (en) | 2003-10-09 | 2004-10-12 | Analgesic compounds, their synthesis and pharmaceutical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004020494D1 true DE602004020494D1 (de) | 2009-05-20 |
Family
ID=33132107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004020494T Active DE602004020494D1 (de) | 2003-10-09 | 2004-10-12 | Analgetische verbindungen, deren synthese und pharmazeutische zusammensetzungen, die diese enthalten |
Country Status (9)
Country | Link |
---|---|
US (1) | US6806291B1 (de) |
EP (1) | EP1682496B1 (de) |
JP (2) | JP4568726B2 (de) |
AT (1) | ATE427931T1 (de) |
AU (1) | AU2004279880B2 (de) |
CA (1) | CA2544648C (de) |
DE (1) | DE602004020494D1 (de) |
ES (1) | ES2325163T3 (de) |
WO (1) | WO2005035485A2 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU754088B2 (en) * | 1997-09-04 | 2002-11-07 | Demerx, Inc. | Noribogaine in the treatment of pain and drug addiction |
US20070083185A1 (en) * | 2005-09-30 | 2007-04-12 | Darrick Carter | Iontophoretic device and method of delivery of active agents to biological interface |
US20100004171A1 (en) * | 2006-08-08 | 2010-01-07 | Bazan Nicolas G | Therapeutic Methods for Neuropathic Pain |
US8362007B1 (en) | 2010-05-11 | 2013-01-29 | Demerx, Inc. | Substituted noribogaine |
US8765737B1 (en) | 2010-05-11 | 2014-07-01 | Demerx, Inc. | Methods and compositions for preparing and purifying noribogaine |
US9394294B2 (en) | 2010-05-11 | 2016-07-19 | Demerx, Inc. | Methods and compositions for preparing and purifying noribogaine |
US8741891B1 (en) | 2010-06-22 | 2014-06-03 | Demerx, Inc. | N-substituted noribogaine prodrugs |
US8637648B1 (en) | 2010-06-22 | 2014-01-28 | Demerx, Inc. | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
US9586954B2 (en) | 2010-06-22 | 2017-03-07 | Demerx, Inc. | N-substituted noribogaine prodrugs |
US8802832B2 (en) | 2010-06-22 | 2014-08-12 | Demerx, Inc. | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
CN103079571A (zh) | 2010-07-23 | 2013-05-01 | 德莫科斯公司 | 降伊波加因碱组合物 |
EP2481740B1 (de) | 2011-01-26 | 2015-11-04 | DemeRx, Inc. | Verfahren und Zusammensetzungen zur Herstellung von Noribogain aus Voacangin |
US9617274B1 (en) | 2011-08-26 | 2017-04-11 | Demerx, Inc. | Synthetic noribogaine |
US20130096170A1 (en) | 2011-10-14 | 2013-04-18 | Hospira, Inc. | Methods of treating pediatric patients using dexmedetomidine |
WO2013085922A1 (en) | 2011-12-09 | 2013-06-13 | Demerx, Inc. | Phosphate esters of noribogaine |
US8242158B1 (en) * | 2012-01-04 | 2012-08-14 | Hospira, Inc. | Dexmedetomidine premix formulation |
US8877921B2 (en) | 2012-01-25 | 2014-11-04 | Demerx, Inc. | Synthetic voacangine |
US9150584B2 (en) | 2012-01-25 | 2015-10-06 | Demerx, Inc. | Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them |
US9045481B2 (en) | 2012-12-20 | 2015-06-02 | Demerx, Inc. | Substituted noribogaine |
US8940728B2 (en) | 2012-12-20 | 2015-01-27 | Demerx, Inc. | Substituted noribogaine |
US9783535B2 (en) | 2012-12-20 | 2017-10-10 | Demerx, Inc. | Substituted noribogaine |
WO2015195673A2 (en) | 2014-06-18 | 2015-12-23 | Demerx, Inc. | Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them |
CA3073801C (en) * | 2017-08-25 | 2023-07-11 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compositions and methods for ameliorating pain |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3700773A (en) * | 1969-06-25 | 1972-10-24 | Merck & Co Inc | Substituted phenylsulfamyl salicyclic acids and derivatives thereof in the treatment of inflammation |
DE4010536A1 (de) * | 1990-04-02 | 1991-10-10 | Boehringer Mannheim Gmbh | Pharmazeutische waessrige loesung von 4-(2-(benzolsulfonylamino)-ethyl)-phenoxyessigsaeure |
US5554636A (en) | 1995-04-21 | 1996-09-10 | Lsu Medical Center Foundation | N-acylated 4-hydroxphenylamine derivatives with analgesic properties and pharmaceutical compositions containing them |
JP2000103778A (ja) * | 1997-05-15 | 2000-04-11 | Ono Pharmaceut Co Ltd | ベンゼンスルフォンアミド化合物、それらの製造方法およびそれらを有効成分として含有するプロスタグランジンe2受容体拮抗剤 |
IL138686A0 (en) * | 1999-10-01 | 2001-10-31 | Pfizer Prod Inc | α- SULFONYLAMINO HYDROXAMIC ACID INHIBITORS OF MATRIX METALLOPROTEINASES FOR THE TREATMENT OF PERIPHERAL OR CENTRAL NERVOUS SYSTEM DISORDERS |
TWI239942B (en) * | 2001-06-11 | 2005-09-21 | Dainippon Pharmaceutical Co | N-arylphenylacetamide derivative and pharmaceutical composition containing the same |
-
2003
- 2003-10-09 US US10/682,744 patent/US6806291B1/en not_active Expired - Lifetime
-
2004
- 2004-10-12 JP JP2006534463A patent/JP4568726B2/ja not_active Expired - Fee Related
- 2004-10-12 WO PCT/US2004/033609 patent/WO2005035485A2/en active Application Filing
- 2004-10-12 EP EP04794857A patent/EP1682496B1/de not_active Not-in-force
- 2004-10-12 AU AU2004279880A patent/AU2004279880B2/en not_active Ceased
- 2004-10-12 AT AT04794857T patent/ATE427931T1/de not_active IP Right Cessation
- 2004-10-12 DE DE602004020494T patent/DE602004020494D1/de active Active
- 2004-10-12 ES ES04794857T patent/ES2325163T3/es active Active
- 2004-10-12 CA CA2544648A patent/CA2544648C/en not_active Expired - Fee Related
-
2010
- 2010-05-31 JP JP2010124856A patent/JP2010195826A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU2004279880A1 (en) | 2005-04-21 |
CA2544648C (en) | 2011-05-24 |
JP4568726B2 (ja) | 2010-10-27 |
JP2007508325A (ja) | 2007-04-05 |
WO2005035485A3 (en) | 2005-06-09 |
EP1682496B1 (de) | 2009-04-08 |
US6806291B1 (en) | 2004-10-19 |
JP2010195826A (ja) | 2010-09-09 |
CA2544648A1 (en) | 2005-04-21 |
ES2325163T3 (es) | 2009-08-27 |
ATE427931T1 (de) | 2009-04-15 |
WO2005035485A2 (en) | 2005-04-21 |
AU2004279880B2 (en) | 2010-09-16 |
EP1682496A2 (de) | 2006-07-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |