ATE410152T1 - Therapeutisches system mit amoxicillin und clavulansäure - Google Patents
Therapeutisches system mit amoxicillin und clavulansäureInfo
- Publication number
- ATE410152T1 ATE410152T1 AT04713281T AT04713281T ATE410152T1 AT E410152 T1 ATE410152 T1 AT E410152T1 AT 04713281 T AT04713281 T AT 04713281T AT 04713281 T AT04713281 T AT 04713281T AT E410152 T1 ATE410152 T1 AT E410152T1
- Authority
- AT
- Austria
- Prior art keywords
- amoxicillin
- clavulanic acid
- therapeutic system
- dosage
- pharmaceutical composition
- Prior art date
Links
- QJVHTELASVOWBE-AGNWQMPPSA-N (2s,5r,6r)-6-[[(2r)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;(2r,3z,5r)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21.C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 QJVHTELASVOWBE-AGNWQMPPSA-N 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 abstract 1
- 229960003022 amoxicillin Drugs 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 abstract 1
- DWHGNUUWCJZQHO-ZVDZYBSKSA-M potassium;(2s,5r,6r)-6-[[(2r)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;(2r,3z,5r)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate Chemical compound [K+].[O-]C(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21.C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 DWHGNUUWCJZQHO-ZVDZYBSKSA-M 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SI200300044A SI21401A (sl) | 2003-02-21 | 2003-02-21 | Terapevtski sistem |
| SI200300245A SI21601A (sl) | 2003-09-24 | 2003-09-24 | Terapevtski sistem |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE410152T1 true ATE410152T1 (de) | 2008-10-15 |
Family
ID=32911559
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04713281T ATE410152T1 (de) | 2003-02-21 | 2004-02-20 | Therapeutisches system mit amoxicillin und clavulansäure |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20060121106A1 (de) |
| EP (1) | EP1596841B1 (de) |
| AT (1) | ATE410152T1 (de) |
| BR (1) | BRPI0407438A (de) |
| CA (1) | CA2516327C (de) |
| DE (1) | DE602004016963D1 (de) |
| EA (1) | EA011215B1 (de) |
| MX (1) | MXPA05008843A (de) |
| PL (1) | PL213804B1 (de) |
| SI (1) | SI1596841T1 (de) |
| WO (1) | WO2004073695A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090060995A1 (en) * | 2005-01-13 | 2009-03-05 | Kamalinder Kaur Singh | Dispersible sustained release pharmaceutical compositions |
| US7527807B2 (en) | 2000-06-21 | 2009-05-05 | Cubist Pharmaceuticals, Inc. | Compositions and methods for increasing the oral absorption of antimicrobials |
| CA2606386C (en) | 2005-04-29 | 2014-06-10 | Cubist Pharmaceuticals, Inc. | Therapeutic compositions |
| US8357394B2 (en) * | 2005-12-08 | 2013-01-22 | Shionogi Inc. | Compositions and methods for improved efficacy of penicillin-type antibiotics |
| CA2635378C (en) * | 2005-12-08 | 2015-06-16 | Advancis Pharmaceutical Corporation | Pharmaceutical compositions and methods for improved bacterial eradication |
| EP2063862A2 (de) | 2006-09-04 | 2009-06-03 | Matrix Laboratories Ltd | Pharmazeutische formulierung zur verwendung in der hiv-therapie |
| EP2341912B1 (de) | 2008-09-05 | 2014-01-22 | Supernus Pharmaceuticals, Inc. | Verfahren zur behandlung oder abschwächung von aufmerksamkeitsdefizit/hyperaktivitätsstörungen (adhs) |
| BR112012020989A2 (pt) * | 2010-02-24 | 2016-05-03 | Pfizer | composições veterinárias |
| US9987257B2 (en) * | 2012-01-10 | 2018-06-05 | Michael Spector | Pediatric oral suspension formulations of amoxicillin and clavulanate potassium and method for using same |
| AU2013217013B2 (en) * | 2012-02-08 | 2017-04-20 | Supernus Pharmaceuticals, Inc. | Modified release formulations of viloxazine |
| US20140279169A1 (en) * | 2013-03-15 | 2014-09-18 | Toyota Motor Sales, U.S.A., Inc. | Method for generating vehicle repair estimate reports based on predictive estimating |
| US11813361B2 (en) | 2014-04-04 | 2023-11-14 | Pharmaquest International Center, Llp | Disintegrating monolithic modified release tablets containing quadri-layer extended release granules |
| CN118178216A (zh) * | 2024-03-13 | 2024-06-14 | 重庆麦克福新制药有限公司 | 一种阿莫西林胶囊的制备工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5512411B2 (de) * | 1974-03-12 | 1980-04-02 | ||
| US4083956A (en) * | 1976-04-29 | 1978-04-11 | The Procter & Gamble Company | Anhydrous antiperspirant creams |
| US5443459A (en) * | 1991-01-30 | 1995-08-22 | Alza Corporation | Osmotic device for delayed delivery of agent |
| GB9407386D0 (en) * | 1994-04-14 | 1994-06-08 | Smithkline Beecham Plc | Pharmaceutical formulation |
| JP2959423B2 (ja) * | 1994-12-01 | 1999-10-06 | シオノギクオリカプス株式会社 | カプセル用皮膜組成物 |
| WO2002030392A2 (en) * | 2000-10-12 | 2002-04-18 | Beecham Pharmaceuticals (Pte) Limited | Formulation containing amoxicillin |
-
2004
- 2004-02-20 CA CA2516327A patent/CA2516327C/en not_active Expired - Fee Related
- 2004-02-20 PL PL377683A patent/PL213804B1/pl unknown
- 2004-02-20 AT AT04713281T patent/ATE410152T1/de not_active IP Right Cessation
- 2004-02-20 EP EP04713281A patent/EP1596841B1/de not_active Expired - Lifetime
- 2004-02-20 SI SI200430999T patent/SI1596841T1/sl unknown
- 2004-02-20 BR BR0407438-6A patent/BRPI0407438A/pt not_active IP Right Cessation
- 2004-02-20 WO PCT/SI2004/000010 patent/WO2004073695A1/en not_active Ceased
- 2004-02-20 EA EA200501223A patent/EA011215B1/ru not_active IP Right Cessation
- 2004-02-20 US US10/545,111 patent/US20060121106A1/en not_active Abandoned
- 2004-02-20 DE DE602004016963T patent/DE602004016963D1/de not_active Expired - Lifetime
- 2004-02-20 MX MXPA05008843A patent/MXPA05008843A/es not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA05008843A (es) | 2005-10-18 |
| CA2516327C (en) | 2012-04-17 |
| BRPI0407438A (pt) | 2006-02-07 |
| EA200501223A1 (ru) | 2006-04-28 |
| US20060121106A1 (en) | 2006-06-08 |
| PL213804B1 (pl) | 2013-05-31 |
| EP1596841B1 (de) | 2008-10-08 |
| DE602004016963D1 (en) | 2008-11-20 |
| SI1596841T1 (sl) | 2009-06-30 |
| CA2516327A1 (en) | 2004-09-02 |
| WO2004073695A1 (en) | 2004-09-02 |
| EA011215B1 (ru) | 2009-02-27 |
| EP1596841A1 (de) | 2005-11-23 |
| PL377683A1 (pl) | 2006-02-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |