TNSN03123A1 - Inhibiteur de pde 4 et agent anticholinergique en association pour le traitement de maladies obstructives des voies aeriennes - Google Patents
Inhibiteur de pde 4 et agent anticholinergique en association pour le traitement de maladies obstructives des voies aeriennesInfo
- Publication number
- TNSN03123A1 TNSN03123A1 TNPCT/EP2002/005726A TNSN03123A TNSN03123A1 TN SN03123 A1 TNSN03123 A1 TN SN03123A1 TN SN03123 A TNSN03123 A TN SN03123A TN SN03123 A1 TNSN03123 A1 TN SN03123A1
- Authority
- TN
- Tunisia
- Prior art keywords
- treatment
- inhibitor
- pde
- anticholinergic agent
- obstructive airway
- Prior art date
Links
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 title abstract 3
- 239000000812 cholinergic antagonist Substances 0.000 title abstract 3
- 229940123932 Phosphodiesterase 4 inhibitor Drugs 0.000 title abstract 2
- 230000000414 obstructive effect Effects 0.000 title abstract 2
- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 title abstract 2
- 208000023504 respiratory system disease Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 1
- LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical compound O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 abstract 1
- 229940110309 tiotropium Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
LA PRESENTE INVENTION CONCERNE UNE ASSOCITION D'UN INHIBITEUR DE PDE4 SELECTIF ET D'UN AGENT ANTICHOLINERGIQUE POUR UNE ADMINISTRATION, SIMULTANEE, SEQUENTIELLE OU DISTNCTE, PAR INHALATION, DANS LE TRAITEMENT D'UNE MALADIE OBSTRUCTIVE DES VOIES AERIENNES OU UNE AUTRE MALADIE INFLAMMATOIRE, SOUS RESERVE QUE L'AGENT ANTI-CHOLINERGIQUE NE SOIT PAS UN SEL DE TIOTROPIUM.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29360601P | 2001-05-25 | 2001-05-25 | |
GB0129396A GB0129396D0 (en) | 2001-12-07 | 2001-12-07 | Pharmaceutical combination |
GB0210240A GB0210240D0 (en) | 2002-05-03 | 2002-05-03 | Pharmaceutical combination |
Publications (1)
Publication Number | Publication Date |
---|---|
TNSN03123A1 true TNSN03123A1 (fr) | 2005-12-23 |
Family
ID=27256347
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNPCT/EP2002/005726A TNSN03123A1 (fr) | 2001-05-25 | 2003-07-08 | Inhibiteur de pde 4 et agent anticholinergique en association pour le traitement de maladies obstructives des voies aeriennes |
Country Status (25)
Country | Link |
---|---|
US (1) | US20040147544A1 (fr) |
EP (1) | EP1395288A1 (fr) |
JP (1) | JP2005508861A (fr) |
KR (1) | KR20040007605A (fr) |
CN (1) | CN1511042A (fr) |
AP (1) | AP2003002909A0 (fr) |
BG (1) | BG108382A (fr) |
BR (1) | BR0209992A (fr) |
CA (1) | CA2446613A1 (fr) |
CO (1) | CO5640041A2 (fr) |
CR (1) | CR7152A (fr) |
CZ (1) | CZ20033150A3 (fr) |
EE (1) | EE200300585A (fr) |
HU (1) | HUP0400037A2 (fr) |
IL (1) | IL158776A0 (fr) |
MA (1) | MA27027A1 (fr) |
MX (1) | MXPA03010162A (fr) |
NO (1) | NO20035204D0 (fr) |
NZ (1) | NZ529335A (fr) |
OA (1) | OA12610A (fr) |
PA (1) | PA8546001A1 (fr) |
PL (1) | PL367085A1 (fr) |
SK (1) | SK14312003A3 (fr) |
TN (1) | TNSN03123A1 (fr) |
WO (1) | WO2002096463A1 (fr) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
DE10230769A1 (de) * | 2002-07-09 | 2004-01-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und PDE-IV-Inhibitoren |
US20040058950A1 (en) * | 2002-07-09 | 2004-03-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors |
CA2519682A1 (fr) * | 2003-03-28 | 2004-10-07 | Altana Pharma Ag | Association synergique contenant du roflumilast et un agent anticholinergique selectionne parmi les sels d'ipratropium, d'oxitropium et de tiotropium et destinee au traitement de maladies respiratoires |
PT1610787E (pt) * | 2003-03-28 | 2008-04-23 | Nycomed Gmbh | Associação sinérgica compreendendo roflumilast e um agente anticolinérgico seleccionado de sais de tiotrópio para o tratamento de doenças respiratórias |
RU2006132043A (ru) * | 2004-02-06 | 2008-03-20 | МЕДА Фарма ГмбХ унд Ко.КГ (DE) | Комбинация и фармацевтический препарат для лечения ринита |
SI1713471T1 (sl) * | 2004-02-06 | 2012-07-31 | Meda Pharma Gmbh & Co Kg | Kombinacija antiholinergikov in inhibitorjev fosfodiesteraze tipa za zdravljenje respiratornih bolezni |
PT1713473E (pt) | 2004-02-06 | 2013-05-13 | Meda Pharma Gmbh & Co Kg | Combinação de anticolinérgicos e glucocorticóides para o tratamento a longo prazo de asma e copd |
WO2005102344A1 (fr) * | 2004-04-27 | 2005-11-03 | Kyowa Hakko Kogyo Co., Ltd. | Composition pharmaceutique |
PL1634595T3 (pl) * | 2004-08-19 | 2009-01-30 | Rottapharm Spa | Pochodne N-fenylobenzamidu jako leki do leczenia COPD |
MX2007011273A (es) | 2005-03-16 | 2007-11-08 | Meda Pharma Gmbh & Co Kg | La combinacion de anticolinergicos y antagonistas del receptor de leucotrieno para el tratamiento de enfermedades respiratorias. |
GB0511066D0 (en) * | 2005-05-31 | 2005-07-06 | Novartis Ag | Organic compounds |
JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス,インコーポレイティド | ムスカリン性受容体調節による神経発生 |
EP2258359A3 (fr) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenèse par modulation des récepteurs muscariniques avec sabcomeline |
KR100696432B1 (ko) * | 2005-08-31 | 2007-03-19 | 김용환 | 건강진단용 팬티 |
EP1948167A1 (fr) * | 2005-10-19 | 2008-07-30 | Ranbaxy Laboratories, Ltd. | Compositions d'inhibiteurs de la phosphodiesterase de type iv |
AU2006304787A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
CA2625210A1 (fr) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Modulation de la neurogenese dont la mediation est assuree par recepteur gaba |
AU2006329042B2 (en) | 2005-12-21 | 2012-02-02 | Meda Pharma Gmbh & Co Kg | Combination of anticholinergics, glucocorticoids, beta2-agonists, PDE4 inhibitor and antileukotriene for the treatment of inflammatory diseases |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
EP2100598A1 (fr) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques |
EP2100599A1 (fr) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques |
WO2010099217A1 (fr) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation de neurogenèse à l'aide de combinaisons de d-cyclosérine |
EP2510928A1 (fr) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium pour l'amélioration du sommeil des patients avec des maldadies respiratoires |
WO2013106547A1 (fr) | 2012-01-10 | 2013-07-18 | President And Fellows Of Harvard College | Composés promoteurs de réplication des cellules bêta et leurs procédés d'utilisation |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5552407A (en) * | 1993-06-11 | 1996-09-03 | New York University Medical Center | Anhydroecgonine compounds and their use as anticholinergic agents |
US6004974A (en) * | 1995-06-06 | 1999-12-21 | Pfizer Inc | Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-α]pyridines |
US20020193393A1 (en) * | 2001-03-07 | 2002-12-19 | Michel Pairet | Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors |
-
2002
- 2002-05-24 JP JP2002592972A patent/JP2005508861A/ja not_active Withdrawn
- 2002-05-24 AP APAP/P/2003/002909A patent/AP2003002909A0/en unknown
- 2002-05-24 US US10/478,755 patent/US20040147544A1/en not_active Abandoned
- 2002-05-24 EE EEP200300585A patent/EE200300585A/xx unknown
- 2002-05-24 BR BR0209992-6A patent/BR0209992A/pt not_active IP Right Cessation
- 2002-05-24 NZ NZ529335A patent/NZ529335A/en unknown
- 2002-05-24 CZ CZ20033150A patent/CZ20033150A3/cs unknown
- 2002-05-24 EP EP02750977A patent/EP1395288A1/fr not_active Withdrawn
- 2002-05-24 HU HU0400037A patent/HUP0400037A2/hu unknown
- 2002-05-24 CN CNA028104986A patent/CN1511042A/zh active Pending
- 2002-05-24 WO PCT/EP2002/005726 patent/WO2002096463A1/fr not_active Application Discontinuation
- 2002-05-24 PA PA20028546001A patent/PA8546001A1/es unknown
- 2002-05-24 IL IL15877602A patent/IL158776A0/xx unknown
- 2002-05-24 PL PL02367085A patent/PL367085A1/xx not_active Application Discontinuation
- 2002-05-24 KR KR10-2003-7015352A patent/KR20040007605A/ko not_active Application Discontinuation
- 2002-05-24 SK SK1431-2003A patent/SK14312003A3/sk not_active Application Discontinuation
- 2002-05-24 OA OA1200300304A patent/OA12610A/en unknown
- 2002-05-24 CA CA002446613A patent/CA2446613A1/fr not_active Abandoned
- 2002-05-24 MX MXPA03010162A patent/MXPA03010162A/es unknown
-
2003
- 2003-07-08 TN TNPCT/EP2002/005726A patent/TNSN03123A1/fr unknown
- 2003-11-19 CR CR7152A patent/CR7152A/es not_active Application Discontinuation
- 2003-11-19 CO CO03102140A patent/CO5640041A2/es not_active Application Discontinuation
- 2003-11-20 MA MA27408A patent/MA27027A1/fr unknown
- 2003-11-24 BG BG108382A patent/BG108382A/bg unknown
- 2003-11-24 NO NO20035204A patent/NO20035204D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US20040147544A1 (en) | 2004-07-29 |
CZ20033150A3 (cs) | 2004-06-16 |
CR7152A (es) | 2004-02-23 |
HUP0400037A2 (hu) | 2004-04-28 |
NO20035204D0 (no) | 2003-11-24 |
CN1511042A (zh) | 2004-07-07 |
MXPA03010162A (es) | 2004-03-10 |
PA8546001A1 (es) | 2003-12-30 |
AP2003002909A0 (en) | 2003-12-31 |
CA2446613A1 (fr) | 2002-12-05 |
SK14312003A3 (sk) | 2004-08-03 |
EE200300585A (et) | 2004-04-15 |
IL158776A0 (en) | 2004-05-12 |
EP1395288A1 (fr) | 2004-03-10 |
KR20040007605A (ko) | 2004-01-24 |
PL367085A1 (en) | 2005-02-21 |
BR0209992A (pt) | 2004-04-06 |
BG108382A (bg) | 2004-12-30 |
JP2005508861A (ja) | 2005-04-07 |
CO5640041A2 (es) | 2006-05-31 |
WO2002096463A1 (fr) | 2002-12-05 |
OA12610A (en) | 2006-06-09 |
MA27027A1 (fr) | 2004-12-20 |
NZ529335A (en) | 2005-09-30 |
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