SV1997000032A - Virosomas cationicos como sistema de transferencia para material genetico. - Google Patents

Virosomas cationicos como sistema de transferencia para material genetico.

Info

Publication number
SV1997000032A
SV1997000032A SV1997000032A SV1997000032A SV1997000032A SV 1997000032 A SV1997000032 A SV 1997000032A SV 1997000032 A SV1997000032 A SV 1997000032A SV 1997000032 A SV1997000032 A SV 1997000032A SV 1997000032 A SV1997000032 A SV 1997000032A
Authority
SV
El Salvador
Prior art keywords
virosomes
transfer system
genetic material
cationic virosomes
membrane
Prior art date
Application number
SV1997000032A
Other languages
English (en)
Spanish (es)
Inventor
Klein Peter
Gluck Reinhard
Walti Ernst Rudolf
Original Assignee
Nika Health Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nika Health Products Ltd filed Critical Nika Health Products Ltd
Publication of SV1997000032A publication Critical patent/SV1997000032A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SV1997000032A 1996-05-08 1997-05-07 Virosomas cationicos como sistema de transferencia para material genetico. SV1997000032A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96107282 1996-05-08

Publications (1)

Publication Number Publication Date
SV1997000032A true SV1997000032A (es) 1998-03-27

Family

ID=8222763

Family Applications (1)

Application Number Title Priority Date Filing Date
SV1997000032A SV1997000032A (es) 1996-05-08 1997-05-07 Virosomas cationicos como sistema de transferencia para material genetico.

Country Status (28)

Country Link
US (1) US6210708B1 (Direct)
EP (1) EP0902682A2 (Direct)
JP (1) JP2000509404A (Direct)
KR (1) KR100536983B1 (Direct)
CN (1) CN1271992C (Direct)
AR (1) AR007054A1 (Direct)
AU (1) AU710170B2 (Direct)
BG (1) BG102880A (Direct)
BR (1) BR9709224A (Direct)
CA (1) CA2253561A1 (Direct)
CO (1) CO4600638A1 (Direct)
CZ (1) CZ299809B6 (Direct)
EA (1) EA003130B1 (Direct)
GT (1) GT199700058A (Direct)
HR (1) HRP970234B1 (Direct)
HU (1) HUP9901790A3 (Direct)
ID (1) ID17934A (Direct)
NO (1) NO327726B1 (Direct)
NZ (1) NZ332666A (Direct)
OA (1) OA10916A (Direct)
PA (1) PA8429201A1 (Direct)
PE (1) PE65198A1 (Direct)
PL (1) PL199201B1 (Direct)
SK (1) SK152698A3 (Direct)
SV (1) SV1997000032A (Direct)
TN (1) TNSN97080A1 (Direct)
WO (1) WO1997041834A1 (Direct)
ZA (1) ZA973885B (Direct)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030113347A1 (en) * 1991-05-08 2003-06-19 Schweiz. Serum- & Impfinstitut Bern Immunostimulating and immunopotentiating reconstituted influenza virosomes and vaccines containing them
EP1011735A1 (en) * 1997-09-08 2000-06-28 Promega Corporation METHOD OF $i(IN VIVO) TRANSFORMATION UTILIZING LIPID VEHICLES
SE513149C2 (sv) * 1997-12-05 2000-07-17 Katarina Edwards Läkemedelsdistributionssystem med tvåstegsmålsökning, till specifika celler eller vävnad och till dess cellkärna
GB9813100D0 (en) * 1998-06-18 1998-08-19 Secr Defence Method of forming liposomes
CA2388053A1 (en) * 1999-10-08 2001-04-19 Nika Health Products Limited Cationic dosper virosomes
WO2001044023A1 (de) * 1999-12-17 2001-06-21 Duerschinger Guenter Induktiv aktivierbare zündkapsel für insassen-rückhaltesysteme und prüfschaltung für diese zündkapsel
US20030139361A1 (en) * 2000-01-21 2003-07-24 Kazuhiro Yuda Drug for gene therapy
JP2004536607A (ja) * 2001-07-23 2004-12-09 オニックス ファーマシューティカルズ,インコーポレイティド 標的化されたヒト癌細胞において選択的に複製するウイルス変異体
KR100411234B1 (ko) * 2001-08-14 2003-12-18 한국과학기술원 올리고뉴클레오티드 혼성화 미셀 및 그의 제조방법
WO2003038103A1 (en) * 2001-10-29 2003-05-08 Atso Raasmaja Method for gene transfection using synergistic combinations of cationic lipids and cationic polymers
US20040028687A1 (en) * 2002-01-15 2004-02-12 Waelti Ernst Rudolf Methods and compositions for the targeted delivery of therapeutic substances to specific cells and tissues
US20040176283A1 (en) * 2002-04-01 2004-09-09 Robinson John A. Methods and compositions for the design of synthetic vaccines
EA008497B1 (ru) * 2002-11-21 2007-06-29 Певион Биотех Лтд. Высокоэффективные способные к слиянию везикулы, способ их получения и фармацевтическая композиция, их содержащая
CA2543257C (en) 2003-10-24 2013-12-31 Gencia Corporation Methods and compositions for delivering polynucleotides
US8062891B2 (en) 2003-10-24 2011-11-22 Gencia Corporation Nonviral vectors for delivering polynucleotides to plants
US20090208478A1 (en) * 2003-10-24 2009-08-20 Gencia Corporation Transducible polypeptides for modifying metabolism
US8507277B2 (en) 2003-10-24 2013-08-13 Gencia Corporation Nonviral vectors for delivering polynucleotides
US20090123468A1 (en) 2003-10-24 2009-05-14 Gencia Corporation Transducible polypeptides for modifying metabolism
US8133733B2 (en) 2003-10-24 2012-03-13 Gencia Corporation Nonviral vectors for delivering polynucleotides to target tissues
DE102004057303A1 (de) * 2004-11-26 2006-06-01 Merck Patent Gmbh Stabile Kristallmodifikationen von DOTAP Chlorid
US20070172520A1 (en) * 2005-11-18 2007-07-26 University Of South Florida Immunotargeting of Nonionic Surfactant Vesicles
EP2064229B1 (en) * 2006-09-15 2015-08-12 Ottawa Hospital Research Institute Oncolytic rhabdovirus
KR101242113B1 (ko) * 2010-10-22 2013-03-19 고마바이오텍(주) 유전자 전달용 양이온성 센다이 f/hn 바이로좀 복합체
WO2013032643A2 (en) * 2011-08-31 2013-03-07 Dicerna Pharmaceuticals, Inc. Lipids capable of conformational change and their use in formulations to deliver therapeutic agents to cells
US20140335117A1 (en) * 2011-10-07 2014-11-13 Skau Aps Identification and Attenuation of the Immunosuppressive Domains in Fusion Proteins of Enveloped RNA Viruses
MX383392B (es) 2016-09-27 2025-03-13 Camurus Ab Mezclas y formulaciones que comprenden una sal de alquil amonio de ácido etilendiaminotetraacético (edta).
CN109055432B (zh) * 2018-08-16 2020-10-13 南京科佰生物科技有限公司 慢病毒感染试剂及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261975A (en) 1979-09-19 1981-04-14 Merck & Co., Inc. Viral liposome particle
US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
PL296382A1 (en) * 1991-02-02 1993-11-02 Nika Health Products Ltd Li Li Artificial membrane beads containing functionally active peptides responsible for fusion as a drug administering system
AU655823B2 (en) * 1991-05-08 1995-01-12 Crucell Switzerland Ag Immunostimulating and immunopotentiating reconstituted influenza virosomes and vaccines containing them
AU3614493A (en) 1992-02-04 1993-09-01 Chiron Corporation Non-toxic lipid vaccine formulations
US5631237A (en) 1992-12-22 1997-05-20 Dzau; Victor J. Method for producing in vivo delivery of therapeutic agents via liposomes
US5578475A (en) * 1993-07-12 1996-11-26 Life Technologies, Inc. Composition and methods for transfecting eukaryotic cells
EP0762870B1 (en) * 1994-05-31 2002-09-11 INEX Pharmaceutical Corp. Virosome-mediated intracellular delivery of therapeutic agents
FR2726764B1 (fr) 1994-11-14 1997-01-31 Pasteur Merieux Serums Vacc Adjuvant pour composition vaccinale

Also Published As

Publication number Publication date
HUP9901790A2 (hu) 1999-08-30
EA003130B1 (ru) 2003-02-27
EA199800992A1 (ru) 1999-06-24
NO985137D0 (no) 1998-11-04
CN1225007A (zh) 1999-08-04
CO4600638A1 (es) 1998-05-08
KR20000010780A (ko) 2000-02-25
AU710170B2 (en) 1999-09-16
EP0902682A2 (en) 1999-03-24
BR9709224A (pt) 1999-08-10
NZ332666A (en) 2000-05-26
BG102880A (en) 1999-05-31
KR100536983B1 (ko) 2006-06-29
ZA973885B (en) 1998-11-06
ID17934A (id) 1998-02-12
CN1271992C (zh) 2006-08-30
CA2253561A1 (en) 1997-11-13
CZ299809B6 (cs) 2008-12-03
NO327726B1 (no) 2009-09-14
OA10916A (en) 2003-02-21
CZ361498A3 (cs) 1999-03-17
HRP970234B1 (en) 2002-04-30
US6210708B1 (en) 2001-04-03
PE65198A1 (es) 1998-10-16
AR007054A1 (es) 1999-10-13
AU2776697A (en) 1997-11-26
PL329853A1 (en) 1999-04-12
HRP970234A2 (en) 1998-06-30
PL199201B1 (pl) 2008-08-29
HUP9901790A3 (en) 2010-11-29
PA8429201A1 (es) 2000-05-24
NO985137L (no) 1999-01-04
GT199700058A (es) 1998-10-29
TNSN97080A1 (fr) 2005-03-15
WO1997041834A1 (en) 1997-11-13
JP2000509404A (ja) 2000-07-25
SK152698A3 (en) 1999-05-07

Similar Documents

Publication Publication Date Title
SV1997000032A (es) Virosomas cationicos como sistema de transferencia para material genetico.
ATE254664T1 (de) Renilla luciferase und green fluorescent protein fusionsgene
ES2119250T3 (es) Composiciones y metodos para estimular el crecimiento y diferenciacion de megacariocitos.
FI964536A7 (fi) DNA-rakenne homologisen rekombinaation suorittamiseksi ja sen käyttöjä
ES2146775T3 (es) Tratamiento de terapia genica de enfermedades del sistema nervioso central (snc) mediante un principio activo especifico de las celulas e independiente del ciclo celular.
DE69027526D1 (de) Herstellung von proteinen mittels homologer rekombination
ES2107537T3 (es) Vehiculo inmunoaislante biocompatible implantable para suministrar productos terapeuticos seleccionados.
PT1077072E (pt) Processo in vitro para produzir uma protese homologa de valvula cardiaca ou uma protese homologa de vaso sanguineo
BR9807966A (pt) ácido nucleico isolado, cassete e vetor de expressão, célula, planta, progênie, semente, processos para produzir uma planta, pra induzir a produção de pelo menos um dentre ácido gama linolênico (gla) ou ácido octadecatetraeÈnico (ota) em uma planta deficiente ou com falta de gla, para diminuir a produção de um gene de sìntese de ácido graxo ou metabolismo de lipìdeo em uma planta, e, para co-suprimir um gene de sìntese de ácido graxo ou metabolismo de lipìdeos nativo em uma planta.
MX9207397A (es) Recipientes para cultivo de celulas que tienen hileras interiores y metodo para cultivar celulas en los mismos.
BR0210599A (pt) Uso de monóxido de carbono, método para manutenção de uma célula animal in vitro, artigo de manufatura, bem como meio celular estéril
ATE211166T1 (de) Zellkulturmatrix und biologisch abbaubare dreidimensionale matrix auf hyaluronsäurederivatbasis
BR9908499A (pt) Linhagens celulares embrionárias ousemelhantes a tronco produzidas portransplante nuclear de espécies cruzado
Higashi et al. A novel transfection method for mammalian cells using calcium alginate microbeads
ATE400654T1 (de) Neues säugetiergen bc1-w, welches zur bc1-2 familie apoptose-kontrollierender gene gehört
ES2165050T3 (es) Nuevos derivados cationicos de colesterilo que contienen grupos polares ciclicos.
DE69817180D1 (de) Zns neuroregenerative zusammensetzungen und deren verwendungen
CN104593417A (zh) 木聚糖酶肠道定向表达载体及其细胞系
EP0808364A4 (en) Human pancreatic cell lines: developments and uses
DE3650065D1 (de) Invasive Mikroorganismen.
ES2507665T3 (es) Recombinación de ADN específica de secuencia en células eucariotas
Zhu et al. Efficient establishment of Guangxi Bama mini-pig transgenic fibroblasts via Xfect polymer transfection
ATE292675T1 (de) Tetrahydropyrimidin-dioxygenase-gen, dadurch kodierte polypeptide und verfahren zur deren herstellung
UY26317A1 (es) Sistema de produccion de trombopoyetina humana por celulas de mamiferos en cultivo
Mubarik et al. Mitochondrial and photosynthetic therapy: A crucial strategy for remodeling cellular metabolic function