SU522798A3 - Способ получени частично гидрированных бензохинолизинов - Google Patents
Способ получени частично гидрированных бензохинолизиновInfo
- Publication number
- SU522798A3 SU522798A3 SU1888530A SU1888530A SU522798A3 SU 522798 A3 SU522798 A3 SU 522798A3 SU 1888530 A SU1888530 A SU 1888530A SU 1888530 A SU1888530 A SU 1888530A SU 522798 A3 SU522798 A3 SU 522798A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- acid
- methyl
- hours
- solution
- benzoquinolysins
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 20
- -1 ethyl ether benzylidene acetoacetic acid Chemical compound 0.000 description 12
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 10
- 229960000583 acetic acid Drugs 0.000 description 10
- 239000012362 glacial acetic acid Substances 0.000 description 10
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 9
- 238000009835 boiling Methods 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 6
- IAKNLKLKKBPMHN-UHFFFAOYSA-N 4h-quinolizine-2-carboxylic acid Chemical compound C1=CC=CC2=CC(C(=O)O)=CCN21 IAKNLKLKKBPMHN-UHFFFAOYSA-N 0.000 description 4
- 239000003208 petroleum Substances 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 3
- 125000004494 ethyl ester group Chemical group 0.000 description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 125000004182 2-chlorophenyl group Chemical group [H]C1=C([H])C(Cl)=C(*)C([H])=C1[H] 0.000 description 1
- 125000004204 2-methoxyphenyl group Chemical group [H]C1=C([H])C(*)=C(OC([H])([H])[H])C([H])=C1[H] 0.000 description 1
- 125000004179 3-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C(Cl)=C1[H] 0.000 description 1
- ZETIVVHRRQLWFW-UHFFFAOYSA-N 3-nitrobenzaldehyde Chemical compound [O-][N+](=O)C1=CC=CC(C=O)=C1 ZETIVVHRRQLWFW-UHFFFAOYSA-N 0.000 description 1
- ABAGNOHSGSJIOD-UHFFFAOYSA-N 5-(3-nitrophenyl)-3-oxopent-4-enoic acid Chemical compound OC(=O)CC(=O)C=CC1=CC=CC([N+]([O-])=O)=C1 ABAGNOHSGSJIOD-UHFFFAOYSA-N 0.000 description 1
- WDJHALXBUFZDSR-UHFFFAOYSA-N Acetoacetic acid Natural products CC(=O)CC(O)=O WDJHALXBUFZDSR-UHFFFAOYSA-N 0.000 description 1
- UMNAEMJLVWHHCX-UHFFFAOYSA-N C(C)C(C(CC(=O)O)=O)=CC1=CC(=CC=C1)[N+](=O)[O-] Chemical compound C(C)C(C(CC(=O)O)=O)=CC1=CC(=CC=C1)[N+](=O)[O-] UMNAEMJLVWHHCX-UHFFFAOYSA-N 0.000 description 1
- FKBSYZCYWFULPS-UHFFFAOYSA-N CCC(=CC1=CC(=CC=C1)Cl)C(=O)CC(=O)O Chemical compound CCC(=CC1=CC(=CC=C1)Cl)C(=O)CC(=O)O FKBSYZCYWFULPS-UHFFFAOYSA-N 0.000 description 1
- WRQNANDWMGAFTP-UHFFFAOYSA-N Methylacetoacetic acid Chemical compound COC(=O)CC(C)=O WRQNANDWMGAFTP-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- WOWBFOBYOAGEEA-UHFFFAOYSA-N diafenthiuron Chemical compound CC(C)C1=C(NC(=S)NC(C)(C)C)C(C(C)C)=CC(OC=2C=CC=CC=2)=C1 WOWBFOBYOAGEEA-UHFFFAOYSA-N 0.000 description 1
- IUUGRMRVVARGML-UHFFFAOYSA-N ethyl 5-(2-methoxyphenyl)-3-oxopent-4-enoate Chemical compound CCOC(=O)CC(=O)C=CC1=CC=CC=C1OC IUUGRMRVVARGML-UHFFFAOYSA-N 0.000 description 1
- LLRQFVMRVPYSCG-UHFFFAOYSA-N ethyl 5-(2-methylphenyl)-3-oxopent-4-enoate Chemical compound CCOC(=O)CC(=O)C=CC1=CC=CC=C1C LLRQFVMRVPYSCG-UHFFFAOYSA-N 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2210623A DE2210623A1 (de) | 1972-03-06 | 1972-03-06 | Teilhydrierte benzochinolizine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU522798A3 true SU522798A3 (ru) | 1976-07-25 |
Family
ID=5837995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1888530A SU522798A3 (ru) | 1972-03-06 | 1973-02-28 | Способ получени частично гидрированных бензохинолизинов |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3907807A (enExample) |
| JP (1) | JPS4899196A (enExample) |
| AT (1) | AT325617B (enExample) |
| BE (1) | BE796277A (enExample) |
| CA (1) | CA994775A (enExample) |
| CH (1) | CH578538A5 (enExample) |
| DD (1) | DD106838A5 (enExample) |
| DE (1) | DE2210623A1 (enExample) |
| FR (1) | FR2181788B1 (enExample) |
| GB (1) | GB1368546A (enExample) |
| HU (1) | HU167213B (enExample) |
| IL (1) | IL41667A (enExample) |
| NL (1) | NL7303132A (enExample) |
| SU (1) | SU522798A3 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4218448A (en) * | 1976-06-24 | 1980-08-19 | E. I. Du Pont De Nemours And Company | Antihypertensive polyfluorohydroxyisopropyl bicyclic and tricyclic carbostyrils |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2245261A (en) * | 1939-08-31 | 1941-06-10 | Eastman Kodak Co | Azo compound and material colored therewith |
| US3341528A (en) * | 1963-11-07 | 1967-09-12 | Warner Lambert Pharmaceutical | Substituted benzoquinolines |
| US3673189A (en) * | 1971-01-05 | 1972-06-27 | American Cyanamid Co | Tetracyclic isoquinoline derivatives |
| US3709887A (en) * | 1971-12-08 | 1973-01-09 | Sandoz Ag | 1-substituted-5,6-dihydro-7h-pyrido(3,2,1-ij)quinazolin-3(3h)-ones and their preparation |
-
1972
- 1972-03-06 DE DE2210623A patent/DE2210623A1/de active Pending
-
1973
- 1973-02-26 DD DD169059A patent/DD106838A5/xx unknown
- 1973-02-28 US US336476A patent/US3907807A/en not_active Expired - Lifetime
- 1973-02-28 SU SU1888530A patent/SU522798A3/ru active
- 1973-03-02 IL IL7341667A patent/IL41667A/xx unknown
- 1973-03-02 CH CH313473A patent/CH578538A5/xx not_active IP Right Cessation
- 1973-03-02 JP JP48024450A patent/JPS4899196A/ja active Pending
- 1973-03-05 CA CA165,211A patent/CA994775A/en not_active Expired
- 1973-03-05 BE BE128372A patent/BE796277A/xx unknown
- 1973-03-06 NL NL7303132A patent/NL7303132A/xx unknown
- 1973-03-06 HU HUBA2889A patent/HU167213B/hu unknown
- 1973-03-06 AT AT197173A patent/AT325617B/de not_active IP Right Cessation
- 1973-03-06 FR FR7307919A patent/FR2181788B1/fr not_active Expired
- 1973-03-06 GB GB1075773A patent/GB1368546A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3907807A (en) | 1975-09-23 |
| BE796277A (fr) | 1973-09-05 |
| HU167213B (enExample) | 1975-09-27 |
| NL7303132A (enExample) | 1973-09-10 |
| IL41667A0 (en) | 1973-05-31 |
| JPS4899196A (enExample) | 1973-12-15 |
| CH578538A5 (enExample) | 1976-08-13 |
| AT325617B (de) | 1975-10-27 |
| FR2181788B1 (enExample) | 1976-12-03 |
| CA994775A (en) | 1976-08-10 |
| DD106838A5 (enExample) | 1974-07-05 |
| FR2181788A1 (enExample) | 1973-12-07 |
| GB1368546A (en) | 1974-09-25 |
| IL41667A (en) | 1975-11-25 |
| DE2210623A1 (de) | 1973-09-20 |
| ATA197173A (de) | 1975-01-15 |
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