SMT202500311T1 - Aceclidina per uso nel trattamento della presbiopia - Google Patents

Aceclidina per uso nel trattamento della presbiopia

Info

Publication number
SMT202500311T1
SMT202500311T1 SM20250311T SMT202500311T SMT202500311T1 SM T202500311 T1 SMT202500311 T1 SM T202500311T1 SM 20250311 T SM20250311 T SM 20250311T SM T202500311 T SMT202500311 T SM T202500311T SM T202500311 T1 SMT202500311 T1 SM T202500311T1
Authority
SM
San Marino
Prior art keywords
aceclidine
presbyopia
treatment
Prior art date
Application number
SM20250311T
Other languages
English (en)
Italian (it)
Inventor
Gerald Horn
Lee Nordan
Original Assignee
Lenz Therapeutics Operations Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lenz Therapeutics Operations Inc filed Critical Lenz Therapeutics Operations Inc
Publication of SMT202500311T1 publication Critical patent/SMT202500311T1/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SM20250311T 2013-08-28 2014-08-22 Aceclidina per uso nel trattamento della presbiopia SMT202500311T1 (it)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201361871215P 2013-08-28 2013-08-28
US201361882998P 2013-09-26 2013-09-26
US201361904510P 2013-11-15 2013-11-15
US201361917620P 2013-12-18 2013-12-18
US201461938438P 2014-02-11 2014-02-11
EP19171214.0A EP3542798B1 (en) 2013-08-28 2014-08-22 Aceclidine for use in the treatment of presbyopia

Publications (1)

Publication Number Publication Date
SMT202500311T1 true SMT202500311T1 (it) 2025-09-12

Family

ID=52584080

Family Applications (1)

Application Number Title Priority Date Filing Date
SM20250311T SMT202500311T1 (it) 2013-08-28 2014-08-22 Aceclidina per uso nel trattamento della presbiopia

Country Status (22)

Country Link
US (1) US9089562B2 (https=)
EP (3) EP3542798B1 (https=)
JP (6) JP6426743B2 (https=)
KR (4) KR20160045147A (https=)
CN (1) CN105792815B (https=)
AU (2) AU2014311558B2 (https=)
CA (1) CA2922802C (https=)
DK (1) DK3542798T3 (https=)
ES (1) ES3028364T3 (https=)
FI (1) FI3542798T3 (https=)
HK (1) HK1225654A1 (https=)
HR (1) HRP20250507T1 (https=)
HU (1) HUE071646T2 (https=)
LT (1) LT3542798T (https=)
MX (2) MX393360B (https=)
PL (1) PL3542798T3 (https=)
PT (1) PT3542798T (https=)
RS (1) RS66821B1 (https=)
SG (1) SG11201601412XA (https=)
SI (1) SI3542798T1 (https=)
SM (1) SMT202500311T1 (https=)
WO (1) WO2015031186A1 (https=)

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Also Published As

Publication number Publication date
CA2922802A1 (en) 2015-03-05
ES3028364T3 (en) 2025-06-19
EP3542798B1 (en) 2025-03-19
PT3542798T (pt) 2025-05-20
AU2019200623B2 (en) 2019-10-03
LT3542798T (lt) 2025-06-10
KR20220129097A (ko) 2022-09-22
AU2019200623A1 (en) 2019-02-21
SG11201601412XA (en) 2016-03-30
JP2021183634A (ja) 2021-12-02
WO2015031186A1 (en) 2015-03-05
EP3038610A1 (en) 2016-07-06
AU2014311558A1 (en) 2016-03-17
JP7358221B2 (ja) 2023-10-10
KR20160045147A (ko) 2016-04-26
JP2025131705A (ja) 2025-09-09
EP4563162A3 (en) 2025-08-20
JP7329019B2 (ja) 2023-08-17
US20150065511A1 (en) 2015-03-05
CA2922802C (en) 2021-04-27
MX393360B (es) 2025-03-24
MX2020002922A (es) 2020-07-22
AU2014311558B2 (en) 2019-01-24
RS66821B1 (sr) 2025-06-30
HUE071646T2 (hu) 2025-09-28
MX2016002623A (es) 2016-09-23
JP2016529297A (ja) 2016-09-23
KR20260008183A (ko) 2026-01-15
HRP20250507T1 (hr) 2025-06-20
KR20230157530A (ko) 2023-11-16
JP6426743B2 (ja) 2018-11-21
JP2019031538A (ja) 2019-02-28
PL3542798T3 (pl) 2025-09-08
HK1225654A1 (zh) 2017-09-15
US9089562B2 (en) 2015-07-28
KR102905081B1 (ko) 2025-12-26
CN105792815A (zh) 2016-07-20
EP3542798A1 (en) 2019-09-25
EP3038610A4 (en) 2017-03-22
DK3542798T3 (da) 2025-05-19
JP2023103400A (ja) 2023-07-26
KR102600484B1 (ko) 2023-11-09
JP2020055851A (ja) 2020-04-09
CN105792815B (zh) 2018-08-28
SI3542798T1 (sl) 2025-07-31
EP4563162A2 (en) 2025-06-04
FI3542798T3 (fi) 2025-05-21

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