SG11201601412XA - Compositions and methods for the treatment of presbyopia - Google Patents

Compositions and methods for the treatment of presbyopia

Info

Publication number
SG11201601412XA
SG11201601412XA SG11201601412XA SG11201601412XA SG11201601412XA SG 11201601412X A SG11201601412X A SG 11201601412XA SG 11201601412X A SG11201601412X A SG 11201601412XA SG 11201601412X A SG11201601412X A SG 11201601412XA SG 11201601412X A SG11201601412X A SG 11201601412XA
Authority
SG
Singapore
Prior art keywords
presbyopia
compositions
treatment
methods
Prior art date
Application number
SG11201601412XA
Inventor
Gerald Horn
Lee Nordan
Original Assignee
Presbyopia Therapies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Presbyopia Therapies Llc filed Critical Presbyopia Therapies Llc
Publication of SG11201601412XA publication Critical patent/SG11201601412XA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11201601412XA 2013-08-28 2014-08-22 Compositions and methods for the treatment of presbyopia SG11201601412XA (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201361871215P 2013-08-28 2013-08-28
US201361882998P 2013-09-26 2013-09-26
US201361904510P 2013-11-15 2013-11-15
US201361917620P 2013-12-18 2013-12-18
US201461938438P 2014-02-11 2014-02-11
PCT/US2014/052256 WO2015031186A1 (en) 2013-08-28 2014-08-22 Compositions and methods for the treatment of presbyopia

Publications (1)

Publication Number Publication Date
SG11201601412XA true SG11201601412XA (en) 2016-03-30

Family

ID=52584080

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201601412XA SG11201601412XA (en) 2013-08-28 2014-08-22 Compositions and methods for the treatment of presbyopia

Country Status (11)

Country Link
US (1) US9089562B2 (en)
EP (2) EP3038610A4 (en)
JP (5) JP6426743B2 (en)
KR (3) KR20160045147A (en)
CN (1) CN105792815B (en)
AU (2) AU2014311558B2 (en)
CA (1) CA2922802C (en)
HK (1) HK1225654A1 (en)
MX (2) MX2016002623A (en)
SG (1) SG11201601412XA (en)
WO (1) WO2015031186A1 (en)

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US9421199B2 (en) 2014-06-24 2016-08-23 Sydnexis, Inc. Ophthalmic composition
WO2016172712A2 (en) 2015-04-23 2016-10-27 Sydnexis, Inc. Ophthalmic composition
US11382909B2 (en) 2014-09-05 2022-07-12 Sydnexis, Inc. Ophthalmic composition
US11052094B2 (en) 2015-05-29 2021-07-06 Sydnexis, Inc. D2O stabilized pharmaceutical formulations
WO2016205071A1 (en) * 2015-06-18 2016-12-22 Presbyopia Therapies, LLC Compositions and methods for the treatment of presbyopia
AU2016280616B2 (en) * 2015-06-18 2020-10-22 Lenz Therapeutics, Inc. Compositions for the improvement of distance vision and the treatment of refractive errors of the eye
US10845622B2 (en) 2015-09-15 2020-11-24 Largan Medical Co., Ltd. Multifocal contact lens and contact lens product
CN106526888B (en) * 2015-09-15 2019-08-06 星欧光学股份有限公司 contact lens product
AU2017311636B2 (en) 2016-08-19 2023-08-10 Orasis Pharmaceuticals Ltd. Ophthalmic pharmaceutical compositions and uses relating thereto
IT201700069664A1 (en) * 2017-06-22 2018-12-22 For Health Pharma S R L NEW OPHTHALMIC FORMULATION BASED ON TROPICAMID
JP7170436B2 (en) * 2017-06-28 2022-11-14 千寿製薬株式会社 Ophthalmic solution containing water-soluble polymer
JP7274475B2 (en) 2017-07-20 2023-05-16 セインダ ファーマシューティカル グアンジョウ コーポレイション Compositions and methods for the treatment of myopia
WO2019112030A1 (en) * 2017-12-08 2019-06-13 千寿製薬株式会社 Aqueous liquid agent including water-soluble polymer
KR20230079489A (en) 2018-04-24 2023-06-07 알러간, 인코포레이티드 Use of pilocarpine hydrochloride for the treatment of ocular conditions
JP2020033290A (en) * 2018-08-29 2020-03-05 興和株式会社 Aqueous composition
WO2020252061A1 (en) * 2019-06-10 2020-12-17 Visus Therapeutics, Inc. Carabachol-bromonidine formulation to enhance anti-presbyopia effects
CN114585365A (en) * 2019-06-10 2022-06-03 视觉治疗股份有限公司 Use of parasympathomimetic agents alone or in combination with one or more alpha agonists to produce multifocal patients in pseudolens patients
KR20220041151A (en) * 2019-07-26 2022-03-31 알러간, 인코포레이티드 Compositions and methods for treating presbyopia
US11273141B2 (en) 2020-05-18 2022-03-15 Vyluma Inc. Low-dose carbachol compositions and methods for treatment of night vision disturbance
US20230190738A1 (en) * 2021-12-16 2023-06-22 Lenz Therapeutics, Inc. Compositions and methods for the treatment of eye conditions
US20220347170A1 (en) * 2021-04-28 2022-11-03 Lenz Therapeutics, Inc. Method of Reducing Brow Ache
KR102415950B1 (en) 2021-07-13 2022-07-05 백두하 Health functional food for eye comprising mixture of chrysanthemum extract, quince extract, and longan meat extract as an active ingredient and manufacturing method thereof
WO2023086878A1 (en) * 2021-11-10 2023-05-19 Visus Therapeutics, Inc. Carbachol formulations to enhance anti-presbyopia effects
WO2023091439A1 (en) * 2021-11-17 2023-05-25 Lenz Therapeutics, Inc. Aceclidine derivatives, compositions thereof and methods of use thereof
US11648247B1 (en) 2021-12-16 2023-05-16 Lenz Therapeutics, Inc. Compositions and methods for the treatment of presbyopia
CN114588156A (en) * 2022-04-22 2022-06-07 温州医科大学附属眼视光医院 Ophthalmic preparation and application thereof in treating presbyopia
KR20240045074A (en) * 2022-09-29 2024-04-05 주식회사태준제약 Ophthalmic composition comprising brimonidine

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Also Published As

Publication number Publication date
KR20230157530A (en) 2023-11-16
HK1225654A1 (en) 2017-09-15
CN105792815B (en) 2018-08-28
JP2019031538A (en) 2019-02-28
KR20160045147A (en) 2016-04-26
JP6426743B2 (en) 2018-11-21
MX2020002922A (en) 2020-07-22
JP2016529297A (en) 2016-09-23
JP2023103400A (en) 2023-07-26
US20150065511A1 (en) 2015-03-05
WO2015031186A1 (en) 2015-03-05
AU2019200623B2 (en) 2019-10-03
JP2021183634A (en) 2021-12-02
CA2922802A1 (en) 2015-03-05
AU2014311558B2 (en) 2019-01-24
CA2922802C (en) 2021-04-27
CN105792815A (en) 2016-07-20
JP7329019B2 (en) 2023-08-17
KR20220129097A (en) 2022-09-22
JP7358221B2 (en) 2023-10-10
KR102600484B1 (en) 2023-11-09
AU2014311558A1 (en) 2016-03-17
EP3038610A4 (en) 2017-03-22
AU2019200623A1 (en) 2019-02-21
JP2020055851A (en) 2020-04-09
US9089562B2 (en) 2015-07-28
EP3038610A1 (en) 2016-07-06
MX2016002623A (en) 2016-09-23
EP3542798A1 (en) 2019-09-25

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