SMT201500199B - Pirrolidinoni eteroaromatici fusi come inibitori di syk - Google Patents

Pirrolidinoni eteroaromatici fusi come inibitori di syk

Info

Publication number
SMT201500199B
SMT201500199B SM201500199T SM201500199T SMT201500199B SM T201500199 B SMT201500199 B SM T201500199B SM 201500199 T SM201500199 T SM 201500199T SM 201500199 T SM201500199 T SM 201500199T SM T201500199 B SMT201500199 B SM T201500199B
Authority
SM
San Marino
Prior art keywords
fused
syk inhibitors
pyrrolidinones
heteroaromatic
heteroaromatic pyrrolidinones
Prior art date
Application number
SM201500199T
Other languages
English (en)
Italian (it)
Inventor
Yasuyoshi Arikawa
Benjamin Jones
Betty Lam
Zhe Nie
Christopher Smith
Masashi Takahashi
Qing Dong
Victoria Feher
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43618073&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT201500199(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of SMT201500199B publication Critical patent/SMT201500199B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Transplantation (AREA)
SM201500199T 2009-12-23 2015-08-17 Pirrolidinoni eteroaromatici fusi come inibitori di syk SMT201500199B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28996909P 2009-12-23 2009-12-23
US38696410P 2010-09-27 2010-09-27
PCT/US2010/061146 WO2011079051A1 (en) 2009-12-23 2010-12-17 Fused heteroaromatic pyrrolidinones as syk inhibitors

Publications (1)

Publication Number Publication Date
SMT201500199B true SMT201500199B (it) 2015-10-30

Family

ID=43618073

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201500199T SMT201500199B (it) 2009-12-23 2015-08-17 Pirrolidinoni eteroaromatici fusi come inibitori di syk

Country Status (42)

Country Link
US (7) US8440689B2 (uk)
EP (4) EP2902392B1 (uk)
JP (7) JP5658274B2 (uk)
KR (1) KR101790255B1 (uk)
CN (1) CN102753548B (uk)
AR (1) AR081797A1 (uk)
AU (1) AU2010333804B2 (uk)
BR (1) BR112012015651B1 (uk)
CA (1) CA2786950C (uk)
CL (1) CL2012001745A1 (uk)
CO (1) CO6592058A2 (uk)
CR (1) CR20120392A (uk)
CY (1) CY1116736T1 (uk)
DK (1) DK2516434T3 (uk)
DO (1) DOP2012000180A (uk)
EA (1) EA021568B1 (uk)
EC (1) ECSP12012057A (uk)
ES (1) ES2545616T3 (uk)
GE (1) GEP20156243B (uk)
HK (1) HK1176054A1 (uk)
HR (1) HRP20150878T1 (uk)
HU (1) HUE025177T2 (uk)
IL (1) IL220509A (uk)
JO (1) JO3108B1 (uk)
MA (1) MA33909B1 (uk)
ME (1) ME02186B (uk)
MX (1) MX2012007402A (uk)
MY (1) MY159257A (uk)
NZ (1) NZ601267A (uk)
PE (1) PE20130188A1 (uk)
PL (1) PL2516434T3 (uk)
PT (1) PT2516434E (uk)
RS (1) RS54180B1 (uk)
SG (1) SG181857A1 (uk)
SI (1) SI2516434T1 (uk)
SM (1) SMT201500199B (uk)
TN (1) TN2012000316A1 (uk)
TW (1) TWI457339B (uk)
UA (1) UA107100C2 (uk)
UY (1) UY33151A (uk)
WO (1) WO2011079051A1 (uk)
ZA (1) ZA201205428B (uk)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2516434T3 (pl) 2009-12-23 2015-11-30 Takeda Pharmaceuticals Co Skondensowane heteroaromatyczne pirolidynony jako inhibitory SYK
KR20140020972A (ko) * 2011-03-28 2014-02-19 에프. 호프만-라 로슈 아게 티아졸로피리미딘 화합물
US9056873B2 (en) 2011-06-22 2015-06-16 Takeda Pharmaceutical Company Limited Substituted 6-aza-isoindolin-1-one derivatives
WO2014051653A1 (en) 2012-09-27 2014-04-03 Portola Pharmaceuticals, Inc. Bicyclic dihydropyridone kinase inhibitors
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