MXPA02005959A - Inhibidores de adenosina cinasa para el tratamiento del nervio optico y el bano retiniano. - Google Patents

Inhibidores de adenosina cinasa para el tratamiento del nervio optico y el bano retiniano.

Info

Publication number
MXPA02005959A
MXPA02005959A MXPA02005959A MXPA02005959A MXPA02005959A MX PA02005959 A MXPA02005959 A MX PA02005959A MX PA02005959 A MXPA02005959 A MX PA02005959A MX PA02005959 A MXPA02005959 A MX PA02005959A MX PA02005959 A MXPA02005959 A MX PA02005959A
Authority
MX
Mexico
Prior art keywords
inhibitors
treatment
optic nerve
retinal damage
adenosine kinase
Prior art date
Application number
MXPA02005959A
Other languages
English (en)
Inventor
Peter G Klimko
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of MXPA02005959A publication Critical patent/MXPA02005959A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MXPA02005959A 1999-12-16 2000-11-28 Inhibidores de adenosina cinasa para el tratamiento del nervio optico y el bano retiniano. MXPA02005959A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17106899P 1999-12-16 1999-12-16
PCT/US2000/032376 WO2001043731A2 (en) 1999-12-16 2000-11-28 Inhibitors of adenosine kinase for the treatment of optic nerve and retinal damage

Publications (1)

Publication Number Publication Date
MXPA02005959A true MXPA02005959A (es) 2003-10-14

Family

ID=22622381

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02005959A MXPA02005959A (es) 1999-12-16 2000-11-28 Inhibidores de adenosina cinasa para el tratamiento del nervio optico y el bano retiniano.

Country Status (9)

Country Link
US (1) US20050282769A1 (es)
EP (1) EP1250128A2 (es)
JP (1) JP2003516962A (es)
AU (1) AU1929801A (es)
BR (1) BR0016415A (es)
CA (1) CA2390821A1 (es)
HK (1) HK1048439A1 (es)
MX (1) MXPA02005959A (es)
WO (1) WO2001043731A2 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0114286D0 (en) 2001-06-12 2001-08-01 Hoffmann La Roche Nucleoside Derivatives
CN106243111B (zh) * 2007-08-02 2019-07-23 米伦纽姆医药公司 合成e1活化酶抑制剂的方法
PT2516434E (pt) 2009-12-23 2015-10-05 Takeda Pharmaceutical Pirrolidinonas heteroaromáticas fundidas como inibidores de syk
US9056873B2 (en) 2011-06-22 2015-06-16 Takeda Pharmaceutical Company Limited Substituted 6-aza-isoindolin-1-one derivatives
SG11201402826YA (en) 2011-12-22 2014-12-30 Alios Biopharma Inc Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
CN108026136A (zh) 2015-08-06 2018-05-11 奇默里克斯公司 作为有用的抗病毒剂的吡咯并嘧啶核苷及其类似物
US11111264B2 (en) 2017-09-21 2021-09-07 Chimerix, Inc. Morphic forms of 4-amino-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4550022A (en) * 1981-10-05 1985-10-29 Alcon Laboratories, Inc. Tissue irrigating solution
US4912092A (en) * 1986-03-27 1990-03-27 The Regents Of The University Of California Methods for increasing extracellular adenosine and for stabilizing mast cells
ES2026198T3 (es) * 1987-07-22 1992-04-16 Farvalsa Ag Compuesto a base de acido valproico solido, estable a la humedad y metodo para su preparacion.
US5864033A (en) * 1989-09-15 1999-01-26 Metabasis Therapeutics, Inc. Adenosine kinase inhibitors
US5674998A (en) * 1989-09-15 1997-10-07 Gensia Inc. C-4' modified adenosine kinase inhibitors
EP0684953A4 (en) * 1993-02-03 1999-12-22 Gensia Inc ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES.
IL108523A0 (en) * 1993-02-03 1994-05-30 Gensia Inc Pharmaceutical compositions containing adenosine kinase inhibitors for preventing or treating conditions involving inflammatory responses and pain
US5780450A (en) * 1995-11-21 1998-07-14 Alcon Laboratories, Inc. Use of adenosine uptake inhibitors for treating retinal or optic nerve head damage

Also Published As

Publication number Publication date
HK1048439A1 (zh) 2003-04-04
WO2001043731A2 (en) 2001-06-21
EP1250128A2 (en) 2002-10-23
WO2001043731A3 (en) 2002-03-21
US20050282769A1 (en) 2005-12-22
AU1929801A (en) 2001-06-25
CA2390821A1 (en) 2001-06-21
BR0016415A (pt) 2002-12-24
JP2003516962A (ja) 2003-05-20

Similar Documents

Publication Publication Date Title
AU7720496A (en) The use of adenosine uptake inhibitors for treating retinal or optic nerve head damage
IL148719A0 (en) Kinase inhibitors as therapeutic agents
ZA200108291B (en) Diaminothiazoles and their use for inhibiting protein kinases.
WO2001044247A3 (en) Agents and methods for the treatment of proliferative diseases
HK1068778A1 (en) Insert for the treatment of dry eye
IL151890A0 (en) Hydroxyphenyl-piperidin 4-ylidene-methyl-benzamide derivatives for the treatment of pain
AU2002307430A1 (en) Method and system for photodisruption of tissue of the eye
AU6910600A (en) Methods for the treatment of mental disorders
HK1049661A1 (en) N-Ä5-ÄÄÄ5-alkyl-2-oxazolylÜmethylÜthioÜ-2-thiazolyn carboxamide inhibitors of cyclin dependent kinases.
HUP0401605A3 (en) Integrin inhibitors for the treatment of eye diseases
EP1409015A4 (en) METHODS OF TREATING OR PREVENTING SKIN DISORDERS USING CD2 BINDING AGENTS
IL137429A0 (en) Methods and compsitions for treating diseases and conditions of the eye
EP1173470A4 (en) TREATMENT OF BONE DISORDERS BASED ON ADRENOMEDULLINE OR ADRENOMEDULLINE AGONISTS
AU5754701A (en) Method of using cox-2 inhibitors in the treatment and prevention of ocular cox-2mediated disorders
MXPA02005959A (es) Inhibidores de adenosina cinasa para el tratamiento del nervio optico y el bano retiniano.
HK1051692A1 (en) Quinolinyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatment of pain.
IL151765A0 (en) Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
AU1794801A (en) Method for treatment and prevention of physiological shock
HU0003409D0 (en) Treatment or prevention of coccidiosis
WO2001044235A3 (en) Agents and methods for the treatment of proliferative diseases
AU2566201A (en) Compounds and methods for the treatment of pain
AU1522101A (en) Heparanase inhibitors for the treatment of heart failure
AU3768800A (en) Treatment of brain changes with myelin protective agents
AU2002342715A1 (en) Novel methods for the treatment and prevention of pain using stress-activated protein kinase inhibitors
HK1042039A1 (en) Use of phanquinone for the treatment or preventionof memory impairment.