SK96196A3 - Process for solubilizing difficultly soluble pharmaceutical actives - Google Patents

Process for solubilizing difficultly soluble pharmaceutical actives Download PDF

Info

Publication number
SK96196A3
SK96196A3 SK961-96A SK96196A SK96196A3 SK 96196 A3 SK96196 A3 SK 96196A3 SK 96196 A SK96196 A SK 96196A SK 96196 A3 SK96196 A3 SK 96196A3
Authority
SK
Slovakia
Prior art keywords
peg
pharmaceutical active
polyethylene glycol
sparingly soluble
soluble pharmaceutical
Prior art date
Application number
SK961-96A
Other languages
English (en)
Slovak (sk)
Inventor
Dadi Jamshed Dhabhar
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of SK96196A3 publication Critical patent/SK96196A3/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK961-96A 1994-01-24 1995-01-24 Process for solubilizing difficultly soluble pharmaceutical actives SK96196A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18557694A 1994-01-24 1994-01-24
PCT/US1995/001018 WO1995019759A1 (fr) 1994-01-24 1995-01-24 Procede pour solubiliser des agents pharmaceutiques difficilement solubles

Publications (1)

Publication Number Publication Date
SK96196A3 true SK96196A3 (en) 1997-03-05

Family

ID=22681571

Family Applications (1)

Application Number Title Priority Date Filing Date
SK961-96A SK96196A3 (en) 1994-01-24 1995-01-24 Process for solubilizing difficultly soluble pharmaceutical actives

Country Status (14)

Country Link
EP (1) EP0741560A1 (fr)
JP (1) JPH09508128A (fr)
CN (1) CN1138827A (fr)
AU (1) AU706890B2 (fr)
BR (1) BR9506564A (fr)
CA (1) CA2181241C (fr)
CZ (1) CZ210496A3 (fr)
FI (1) FI962948A (fr)
MX (1) MX9602955A (fr)
NO (1) NO963052L (fr)
NZ (1) NZ279443A (fr)
PL (1) PL315635A1 (fr)
SK (1) SK96196A3 (fr)
WO (1) WO1995019759A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA975444B (en) * 1996-06-20 1998-12-21 Mcneil Ppc Inc Acetaminophen and meclizine hydrochloride analgesics
WO1998058637A1 (fr) * 1996-06-20 1998-12-30 Mcneil-Ppc Analgesique a base d'acetaminophene et de diphenhydramine
FR2751875B1 (fr) * 1996-08-05 1998-12-24 Scr Newpharm Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation
US5763449A (en) * 1996-08-07 1998-06-09 Ascent Pediatrics, Inc. Pleasant-tasting aqueous liquid composition of a bitter-tasting drug
US6365180B1 (en) * 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
JP2002509103A (ja) 1998-01-20 2002-03-26 アプライド・アナリティカル・インダストリーズ，インコーポレイテッド 経口液体組成物
US20020082307A1 (en) * 1999-01-11 2002-06-27 Dobrozsi Douglas Joseph Compositions having improved stability
US6846495B2 (en) 1999-01-11 2005-01-25 The Procter & Gamble Company Compositions having improved delivery of actives
US20020086878A1 (en) * 1999-01-11 2002-07-04 Douglas Joseph Dobrozsi Compositions having improved stability
US6211246B1 (en) * 1999-06-10 2001-04-03 Mcneil-Ppc, Inc. Rapidly absorbed liquid compositions
FR2796843B1 (fr) * 1999-07-29 2003-05-09 So Ge Val Sa Composition antipyretique concentree et stabilisee a usage veterinaire destine a etre incorporee a l'alimentation des animaux ainsi que procede d'incorporation de cette composition a l'eau de boisson d'animaux
US6251426B1 (en) 1999-09-02 2001-06-26 Banner Pharmacaps, Inc. Ibuprofen-containing softgels
DE10011032A1 (de) * 2000-03-07 2001-09-13 Bayer Ag Acetylsalicylsäure-Lösungen
KR20020069387A (ko) * 2001-02-26 2002-09-04 진양제약주식회사 호박산독실아민 조성물 및 이 조성물을 함유한 연질캅셀제제
JP2004538309A (ja) * 2001-07-31 2004-12-24 ワイエス 不快な味覚をマスキングするためのスクラロース調合物
US7101572B2 (en) * 2001-12-07 2006-09-05 Unilab Pharmatech, Ltd. Taste masked aqueous liquid pharmaceutical composition
CN100379406C (zh) * 2003-09-22 2008-04-09 北京德众万全药物技术开发有限公司 一种难溶性药物微丸的制备方法及包含该微丸的制剂
US8333989B2 (en) * 2005-10-26 2012-12-18 Banner Pharmacaps, Inc. Hydrophilic vehicle-based dual controlled release matrix system
DE102005053066A1 (de) 2005-11-04 2007-05-10 Basf Ag Verwendung von Copolymeren als Solubilisatoren für in Wasser schwerlöslichen Verbindungen
WO2007065846A2 (fr) * 2005-12-09 2007-06-14 Basf Se Utilisation de copolymeres blocs de lactame polyvinylique et d'oxyde de polyalkylene comme solubilisants dans des composes peu solubles dans l'eau
US8637076B2 (en) 2006-06-01 2014-01-28 Cima Labs Inc. Prednisolone salt formulations
JP2008184430A (ja) * 2007-01-30 2008-08-14 Ss Pharmaceut Co Ltd ソフトカプセル
CA2690490C (fr) * 2010-01-19 2012-06-26 Accucaps Industries Limited Formulations pharmaceutiques de loratadine pour encapsulation et combinaisons associees
CA2690488C (fr) * 2010-01-19 2013-06-11 Accucaps Industries Limited Formulations pharmaceutiques de naproxen pour encapsulation molle et combinaisons associees
HUE031208T2 (hu) 2010-01-28 2017-07-28 Eagle Pharmaceuticals Inc Bendamusztin kiszerelései
RS65177B1 (sr) 2012-03-20 2024-03-29 Eagle Pharmaceuticals Inc Formulacije bendamustina
RS64137B1 (sr) 2012-03-20 2023-05-31 Eagle Pharmaceuticals Inc Tečne kompozicije bendamustina za upotrebu u postupku lečenja stanja koja reaguju na bendamustin kod pacijenata kojima su potrebne smanjene zapremine za primenu
CA2898408C (fr) 2013-02-28 2018-01-02 Pfizer Inc. Stabilite amelioree de compositions liquides nouvelles
GB201506755D0 (en) * 2015-04-21 2015-06-03 Reckitt Benckiser Llc Novel pharmaceutical formulation
TWI586379B (zh) 2015-06-29 2017-06-11 永信藥品工業股份有限公司 一種製作難溶藥物固體劑型的方法
EP3364955B1 (fr) 2015-10-09 2022-04-20 RB Health (US) LLC Formulation pharmaceutique

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5141961A (en) * 1991-06-27 1992-08-25 Richrdson-Vicks Inc. Process for solubilizing difficulty soluble pharmaceutical actives

Also Published As

Publication number Publication date
CZ210496A3 (en) 1996-12-11
JPH09508128A (ja) 1997-08-19
CA2181241C (fr) 2000-04-25
FI962948A0 (fi) 1996-07-23
FI962948A (fi) 1996-07-23
BR9506564A (pt) 1997-09-02
NO963052D0 (no) 1996-07-22
AU1607595A (en) 1995-08-08
NO963052L (no) 1996-09-24
EP0741560A1 (fr) 1996-11-13
CA2181241A1 (fr) 1995-07-27
WO1995019759A1 (fr) 1995-07-27
CN1138827A (zh) 1996-12-25
AU706890B2 (en) 1999-07-01
PL315635A1 (en) 1996-11-25
NZ279443A (en) 1998-04-27
MX9602955A (es) 1997-06-28

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