SK862002A3 - Catalytic anti-factor viii allo-antibodies - Google Patents

Catalytic anti-factor viii allo-antibodies Download PDF

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Publication number
SK862002A3
SK862002A3 SK86-2002A SK862002A SK862002A3 SK 862002 A3 SK862002 A3 SK 862002A3 SK 862002 A SK862002 A SK 862002A SK 862002 A3 SK862002 A3 SK 862002A3
Authority
SK
Slovakia
Prior art keywords
factor viii
antibodies
allo
inhibitor
asp
Prior art date
Application number
SK86-2002A
Other languages
English (en)
Slovak (sk)
Inventor
Srinivas Kaveri
Sebastien Lacroix-Desmazes
Michel Kazatchkine
Original Assignee
Inst Nat Sante Rech Med
Bayer Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med, Bayer Pharma filed Critical Inst Nat Sante Rech Med
Publication of SK862002A3 publication Critical patent/SK862002A3/sk

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SK86-2002A 1999-07-21 2000-07-18 Catalytic anti-factor viii allo-antibodies SK862002A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99401841A EP1074842A1 (en) 1999-07-21 1999-07-21 Catalytic anti-factor VIII allo-antibodies
PCT/EP2000/006870 WO2001007918A1 (en) 1999-07-21 2000-07-18 Catalytic anti-factor viii allo-antibodies

Publications (1)

Publication Number Publication Date
SK862002A3 true SK862002A3 (en) 2002-06-04

Family

ID=8242069

Family Applications (1)

Application Number Title Priority Date Filing Date
SK86-2002A SK862002A3 (en) 1999-07-21 2000-07-18 Catalytic anti-factor viii allo-antibodies

Country Status (24)

Country Link
US (2) US7507540B1 (cs)
EP (2) EP1074842A1 (cs)
JP (2) JP2003505434A (cs)
KR (1) KR100788435B1 (cs)
CN (1) CN1229646C (cs)
AU (1) AU777615B2 (cs)
BR (1) BR0012613A (cs)
CA (1) CA2379818A1 (cs)
CZ (1) CZ2002248A3 (cs)
EE (1) EE200200034A (cs)
HK (1) HK1044372A1 (cs)
HU (1) HUP0201941A3 (cs)
IL (1) IL147700A0 (cs)
IS (1) IS6238A (cs)
MX (1) MXPA02000752A (cs)
NO (1) NO20020253L (cs)
NZ (1) NZ516702A (cs)
PL (1) PL353739A1 (cs)
RU (1) RU2258935C2 (cs)
SK (1) SK862002A3 (cs)
TR (1) TR200200340T2 (cs)
UA (1) UA75867C2 (cs)
WO (1) WO2001007918A1 (cs)
ZA (1) ZA200200351B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102099580B1 (ko) 2010-11-17 2020-04-10 추가이 세이야쿠 가부시키가이샤 혈액응고 제viii 인자의 기능을 대체하는 기능을 갖는 다중특이성 항원 결합 분자
FR2969761A1 (fr) * 2010-12-22 2012-06-29 Lfb Biotechnologies Procede de dosage d'anticorps diriges contre le facteur viii
TWI700300B (zh) 2014-09-26 2020-08-01 日商中外製藥股份有限公司 中和具有第viii凝血因子(fviii)機能替代活性的物質之抗體
TWI701435B (zh) * 2014-09-26 2020-08-11 日商中外製藥股份有限公司 測定fviii的反應性之方法
WO2017188356A1 (ja) 2016-04-28 2017-11-02 中外製薬株式会社 抗体含有製剤
MX2020003472A (es) 2017-11-01 2020-08-03 Chugai Pharmaceutical Co Ltd Variante e isoforma de anticuerpos con actividad biologica reducida.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5744446A (en) * 1992-04-07 1998-04-28 Emory University Hybrid human/animal factor VIII
WO1994011013A1 (en) * 1992-11-13 1994-05-26 Duke University Chimeric blood coagulation proteins
US5910481A (en) * 1995-11-13 1999-06-08 Immuno Ag Hybrid proteins with modified activity
US5744326A (en) * 1996-03-11 1998-04-28 The Immune Response Corporation Use of viral CIS-acting post-transcriptional regulatory sequences to increase expression of intronless genes containing near-consensus splice sites

Also Published As

Publication number Publication date
PL353739A1 (en) 2003-12-01
NO20020253L (no) 2002-03-13
BR0012613A (pt) 2002-04-09
KR20020042618A (ko) 2002-06-05
HUP0201941A3 (en) 2005-01-28
JP2003505434A (ja) 2003-02-12
UA75867C2 (en) 2006-06-15
HK1044372A1 (zh) 2002-10-18
CN1229646C (zh) 2005-11-30
EP1074842A1 (en) 2001-02-07
CZ2002248A3 (cs) 2002-07-17
EP1196782A1 (en) 2002-04-17
JP2009292823A (ja) 2009-12-17
NO20020253D0 (no) 2002-01-17
IL147700A0 (en) 2002-08-14
TR200200340T2 (tr) 2003-01-21
MXPA02000752A (es) 2003-07-14
AU6824500A (en) 2001-02-13
WO2001007918A1 (en) 2001-02-01
NZ516702A (en) 2003-10-31
KR100788435B1 (ko) 2007-12-24
RU2258935C2 (ru) 2005-08-20
CN1361865A (zh) 2002-07-31
IS6238A (is) 2002-01-16
ZA200200351B (en) 2003-03-26
EE200200034A (et) 2003-06-16
US20090208512A1 (en) 2009-08-20
US7507540B1 (en) 2009-03-24
CA2379818A1 (en) 2001-02-01
AU777615B2 (en) 2004-10-21
HUP0201941A2 (en) 2002-10-28

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