SK80094A3 - Method of preparation of halogenated stereoide dienes - Google Patents

Method of preparation of halogenated stereoide dienes Download PDF

Info

Publication number
SK80094A3
SK80094A3 SK800-94A SK80094A SK80094A3 SK 80094 A3 SK80094 A3 SK 80094A3 SK 80094 A SK80094 A SK 80094A SK 80094 A3 SK80094 A3 SK 80094A3
Authority
SK
Slovakia
Prior art keywords
reagent
halogen
vilsmeier reagent
chloride
vilsmeier
Prior art date
Application number
SK800-94A
Other languages
English (en)
Slovak (sk)
Inventor
Neil H Baine
Donald N Klein
Richard E Mewshaw
Lillian Owings
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of SK80094A3 publication Critical patent/SK80094A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK800-94A 1992-01-06 1993-01-06 Method of preparation of halogenated stereoide dienes SK80094A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81717992A 1992-01-06 1992-01-06
US94134892A 1992-09-04 1992-09-04
PCT/US1993/000079 WO1993014106A1 (en) 1992-01-06 1993-01-06 Halogenation using halo-vilsmeier reagent

Publications (1)

Publication Number Publication Date
SK80094A3 true SK80094A3 (en) 1994-12-07

Family

ID=27124147

Family Applications (1)

Application Number Title Priority Date Filing Date
SK800-94A SK80094A3 (en) 1992-01-06 1993-01-06 Method of preparation of halogenated stereoide dienes

Country Status (23)

Country Link
EP (1) EP0643723A4 (enExample)
JP (1) JPH07505138A (enExample)
KR (1) KR940703849A (enExample)
CN (1) CN1077201A (enExample)
AP (1) AP370A (enExample)
AU (1) AU666167B2 (enExample)
BG (1) BG98887A (enExample)
BR (1) BR9305786A (enExample)
CA (1) CA2127272A1 (enExample)
CZ (1) CZ161994A3 (enExample)
FI (1) FI943214A0 (enExample)
HU (1) HUT68273A (enExample)
IL (1) IL104302A (enExample)
MA (1) MA22761A1 (enExample)
MX (1) MX9300025A (enExample)
NO (1) NO942535D0 (enExample)
NZ (1) NZ246788A (enExample)
OA (1) OA09961A (enExample)
RU (1) RU94038223A (enExample)
SI (1) SI9300006A (enExample)
SK (1) SK80094A3 (enExample)
TW (1) TW300226B (enExample)
WO (1) WO1993014106A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors
US8143428B2 (en) 2004-06-08 2012-03-27 Temple University-Of The Commonwealth System Of Higher Education Heteroaryl sulfones and sulfonamides and therapeutic uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA883034B (en) * 1987-04-29 1989-03-29 Smithkline Beckman Corp Steroid 5-alpha-reductase inhibitors

Also Published As

Publication number Publication date
IL104302A0 (en) 1993-05-13
IL104302A (en) 1998-02-22
TW300226B (enExample) 1997-03-11
AU666167B2 (en) 1996-02-01
MA22761A1 (fr) 1993-10-01
FI943214A7 (fi) 1994-07-05
HU9402030D0 (en) 1994-09-28
AP370A (en) 1994-11-10
SI9300006A (en) 1993-09-30
WO1993014106A1 (en) 1993-07-22
KR940703849A (ko) 1994-12-12
HUT68273A (en) 1995-06-28
FI943214L (fi) 1994-07-05
MX9300025A (es) 1994-01-31
BG98887A (bg) 1995-05-31
CN1077201A (zh) 1993-10-13
AU3434893A (en) 1993-08-03
AP9300473A0 (en) 1993-01-31
JPH07505138A (ja) 1995-06-08
RU94038223A (ru) 1997-04-20
EP0643723A4 (en) 1995-05-10
BR9305786A (pt) 1997-02-18
FI943214A0 (fi) 1994-07-05
EP0643723A1 (en) 1995-03-22
NO942535L (no) 1994-07-05
NO942535D0 (no) 1994-07-05
NZ246788A (en) 1996-11-26
OA09961A (en) 1995-12-11
CA2127272A1 (en) 1993-07-22
CZ161994A3 (en) 1995-03-15

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