SK708189A3 - 2-iminobenzothiazoline derivative, preparation method thereof and pharmaceutical agent containing this derivative - Google Patents

2-iminobenzothiazoline derivative, preparation method thereof and pharmaceutical agent containing this derivative Download PDF

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Publication number
SK708189A3
SK708189A3 SK7081-89A SK708189A SK708189A3 SK 708189 A3 SK708189 A3 SK 708189A3 SK 708189 A SK708189 A SK 708189A SK 708189 A3 SK708189 A3 SK 708189A3
Authority
SK
Slovakia
Prior art keywords
group
formula
derivative
imino
acid
Prior art date
Application number
SK7081-89A
Other languages
English (en)
Slovak (sk)
Other versions
SK278349B6 (en
Inventor
Claude Gueremy
Patrick Jimonet
Serge Mignant
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8816546A external-priority patent/FR2640622B1/fr
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of SK708189A3 publication Critical patent/SK708189A3/sk
Publication of SK278349B6 publication Critical patent/SK278349B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SK7081-89A 1988-12-15 1989-12-14 2-iminobenzothiazoline derivative, preparation method thereof and pharmaceutical agent containing this derivative SK278349B6 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8816546A FR2640622B1 (fr) 1988-12-15 1988-12-15 Derives de l'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
FR898909480A FR2649701B2 (fr) 1988-12-15 1989-07-13 Derives d'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant

Publications (2)

Publication Number Publication Date
SK708189A3 true SK708189A3 (en) 1997-01-08
SK278349B6 SK278349B6 (en) 1997-01-08

Family

ID=26227049

Family Applications (1)

Application Number Title Priority Date Filing Date
SK7081-89A SK278349B6 (en) 1988-12-15 1989-12-14 2-iminobenzothiazoline derivative, preparation method thereof and pharmaceutical agent containing this derivative

Country Status (22)

Country Link
US (1) US5008280A (pt)
EP (1) EP0374040B1 (pt)
JP (1) JPH0733376B2 (pt)
AU (1) AU618432B2 (pt)
CA (1) CA2005590A1 (pt)
CZ (1) CZ280107B6 (pt)
DE (1) DE68905585T2 (pt)
DK (1) DK169967B1 (pt)
ES (1) ES2054068T3 (pt)
FI (1) FI93106C (pt)
FR (1) FR2649701B2 (pt)
GR (1) GR3007788T3 (pt)
HU (1) HU203088B (pt)
IE (1) IE62714B1 (pt)
IL (1) IL92710A (pt)
NO (1) NO173060C (pt)
NZ (1) NZ231793A (pt)
PL (2) PL161369B1 (pt)
PT (1) PT92604B (pt)
RU (1) RU2037489C1 (pt)
SK (1) SK278349B6 (pt)
YU (1) YU47337B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2671081B1 (fr) * 1991-01-02 1994-09-30 Rhone Poulenc Rorer Sa Derives d'imino-2 polyfluoroalkyl-6 heterocyclylalkyl-3 benzothiazoline, leur preparation et les medicaments les contenant.
DE69007196T2 (de) * 1989-07-13 1994-06-30 Rhone Poulenc Sante 2-Imino-3 heterocyclylamino-benzothiazoline, ihre Herstellung und sie enthaltende Arzneimittel.
FR2649702B1 (fr) * 1989-07-13 1991-11-22 Rhone Poulenc Sante Derives d'alkylimino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
US5260297A (en) * 1989-07-13 1993-11-09 Rhone Poulenc Rorer, S.A. 2-imino-3-alkylbenzothiazoline derivatives bearing a heterocyclic substituent on the alkyl group, their preparation and medicinal products containing them.
US5240948A (en) * 1989-12-13 1993-08-31 Rhone-Poulenc Rorer Pharmaceuticals Inc. 3-(3-alkylthiopropyl)benzothiazoline derivatives, their preparation and the medicament containing them
FR2663029B1 (fr) * 1990-06-07 1992-07-31 Rhone Poulenc Sante Derives de benzothiazole, leur preparation et les medicaments les contenant.
FR2678619B1 (fr) * 1991-07-04 1993-09-17 Rhone Poulenc Rorer Sa Derives de 1,2,4-thiadiazolo[3,4-b]benzothiazole, leur preparation et les medicaments les contenant.
FR2726271B1 (fr) * 1994-10-26 1996-12-06 Rhone Poulenc Rorer Sa Derives de 6-polyfluoroalcoxy-2-aminobenzothiazole
FR2741804B1 (fr) * 1995-12-01 1998-01-02 Rhone Poulenc Rorer Sa Application de 2-iminobenzothiazolines dans le traitement de la maladie de parkinson et des syndromes parkinsoniens
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
IL128718A0 (en) 1996-09-27 2000-01-31 Guildford Pharmaceuticals Inc Naaldase compositions
FR2766487B1 (fr) * 1997-07-28 1999-08-27 Rhone Poulenc Rorer Sa Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
AU4537500A (en) 1999-05-12 2000-12-05 Neurosearch A/S Ion channel modulating agents
GB0307067D0 (en) * 2002-12-17 2003-04-30 Aventis Pharma Inc Use of thiazolobenzoheterocycles for treating multiple sclerosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2631163B2 (de) * 1976-07-10 1978-06-29 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 2-Iminobenzothiazolen
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
US4918090A (en) * 1988-01-25 1990-04-17 Warner-Lambert Company Substituted 2-aminbenzothiazoles and derivatives useful as cerebrovascular agents

Also Published As

Publication number Publication date
RU2037489C1 (ru) 1995-06-19
NO895030L (no) 1990-06-18
FI93106C (fi) 1995-02-27
AU618432B2 (en) 1991-12-19
ES2054068T3 (es) 1994-08-01
HUT53625A (en) 1990-11-28
YU47337B (sh) 1995-01-31
NO895030D0 (no) 1989-12-14
DE68905585T2 (de) 1993-09-16
US5008280A (en) 1991-04-16
CA2005590A1 (fr) 1990-06-15
IL92710A0 (en) 1990-09-17
IL92710A (en) 1993-06-10
CZ280107B6 (cs) 1995-10-18
FR2649701B2 (fr) 1991-11-22
SK278349B6 (en) 1997-01-08
FI895981A0 (fi) 1989-12-14
EP0374040A1 (fr) 1990-06-20
GR3007788T3 (pt) 1993-08-31
PL161336B1 (pl) 1993-06-30
EP0374040B1 (fr) 1993-03-24
PT92604A (pt) 1990-06-29
NO173060C (no) 1993-10-20
FI93106B (fi) 1994-11-15
YU236989A (en) 1991-02-28
DK633689A (da) 1990-06-16
DK169967B1 (da) 1995-04-18
DE68905585D1 (de) 1993-04-29
PT92604B (pt) 1995-09-12
DK633689D0 (da) 1989-12-14
IE62714B1 (en) 1995-02-22
NO173060B (no) 1993-07-12
HU203088B (en) 1991-05-28
PL161369B1 (en) 1993-06-30
JPH02223569A (ja) 1990-09-05
CZ708189A3 (en) 1995-06-14
FR2649701A2 (fr) 1991-01-18
AU4618989A (en) 1990-06-21
NZ231793A (en) 1991-03-26
HU896612D0 (en) 1990-02-28
IE894006L (en) 1990-06-15
JPH0733376B2 (ja) 1995-04-12

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