PT92604A - Processo de preparacao de derivados da 2-iminobenzotiazolina e de medicamentos que os contem - Google Patents

Processo de preparacao de derivados da 2-iminobenzotiazolina e de medicamentos que os contem

Info

Publication number
PT92604A
PT92604A PT92604A PT9260489A PT92604A PT 92604 A PT92604 A PT 92604A PT 92604 A PT92604 A PT 92604A PT 9260489 A PT9260489 A PT 9260489A PT 92604 A PT92604 A PT 92604A
Authority
PT
Portugal
Prior art keywords
iminobenzotiazoline
derivatives
products containing
preparation procedure
medicinal products
Prior art date
Application number
PT92604A
Other languages
English (en)
Other versions
PT92604B (pt
Inventor
Patrick Jimonet
Claude Gueremy
Serge Mignani
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8816546A external-priority patent/FR2640622B1/fr
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of PT92604A publication Critical patent/PT92604A/pt
Publication of PT92604B publication Critical patent/PT92604B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PT92604A 1988-12-15 1989-12-15 Processo de preparacao de derivados da 2-iminobenzotiazolina e de medicamentos que os contem PT92604B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8816546A FR2640622B1 (fr) 1988-12-15 1988-12-15 Derives de l'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
FR898909480A FR2649701B2 (fr) 1988-12-15 1989-07-13 Derives d'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant

Publications (2)

Publication Number Publication Date
PT92604A true PT92604A (pt) 1990-06-29
PT92604B PT92604B (pt) 1995-09-12

Family

ID=26227049

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92604A PT92604B (pt) 1988-12-15 1989-12-15 Processo de preparacao de derivados da 2-iminobenzotiazolina e de medicamentos que os contem

Country Status (22)

Country Link
US (1) US5008280A (pt)
EP (1) EP0374040B1 (pt)
JP (1) JPH0733376B2 (pt)
AU (1) AU618432B2 (pt)
CA (1) CA2005590A1 (pt)
CZ (1) CZ280107B6 (pt)
DE (1) DE68905585T2 (pt)
DK (1) DK169967B1 (pt)
ES (1) ES2054068T3 (pt)
FI (1) FI93106C (pt)
FR (1) FR2649701B2 (pt)
GR (1) GR3007788T3 (pt)
HU (1) HU203088B (pt)
IE (1) IE62714B1 (pt)
IL (1) IL92710A (pt)
NO (1) NO173060C (pt)
NZ (1) NZ231793A (pt)
PL (2) PL161336B1 (pt)
PT (1) PT92604B (pt)
RU (1) RU2037489C1 (pt)
SK (1) SK708189A3 (pt)
YU (1) YU47337B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2649702B1 (fr) * 1989-07-13 1991-11-22 Rhone Poulenc Sante Derives d'alkylimino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
US5260297A (en) * 1989-07-13 1993-11-09 Rhone Poulenc Rorer, S.A. 2-imino-3-alkylbenzothiazoline derivatives bearing a heterocyclic substituent on the alkyl group, their preparation and medicinal products containing them.
FR2671081B1 (fr) * 1991-01-02 1994-09-30 Rhone Poulenc Rorer Sa Derives d'imino-2 polyfluoroalkyl-6 heterocyclylalkyl-3 benzothiazoline, leur preparation et les medicaments les contenant.
DK0409692T3 (da) * 1989-07-13 1994-04-05 Rhone Poulenc Sante Derivater af 2-imino-3-heterocycloalkylbenzothiazolin, deres fremstilling og lægemidler med indhold deraf
US5240948A (en) * 1989-12-13 1993-08-31 Rhone-Poulenc Rorer Pharmaceuticals Inc. 3-(3-alkylthiopropyl)benzothiazoline derivatives, their preparation and the medicament containing them
FR2663029B1 (fr) * 1990-06-07 1992-07-31 Rhone Poulenc Sante Derives de benzothiazole, leur preparation et les medicaments les contenant.
FR2678619B1 (fr) * 1991-07-04 1993-09-17 Rhone Poulenc Rorer Sa Derives de 1,2,4-thiadiazolo[3,4-b]benzothiazole, leur preparation et les medicaments les contenant.
FR2726271B1 (fr) * 1994-10-26 1996-12-06 Rhone Poulenc Rorer Sa Derives de 6-polyfluoroalcoxy-2-aminobenzothiazole
FR2741804B1 (fr) * 1995-12-01 1998-01-02 Rhone Poulenc Rorer Sa Application de 2-iminobenzothiazolines dans le traitement de la maladie de parkinson et des syndromes parkinsoniens
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
HUP0001062A3 (en) 1996-09-27 2001-09-28 Guilford Pharmaceuticals Inc B Pharmaceutical compositions of phosphinic acid derivatives having naaladase inhibitor acivity
FR2766487B1 (fr) * 1997-07-28 1999-08-27 Rhone Poulenc Rorer Sa Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
WO2000069838A1 (en) 1999-05-12 2000-11-23 Neurosearch A/S Ion channel modulating agents
GB0307067D0 (en) 2002-12-17 2003-04-30 Aventis Pharma Inc Use of thiazolobenzoheterocycles for treating multiple sclerosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2631163B2 (de) * 1976-07-10 1978-06-29 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 2-Iminobenzothiazolen
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
US4918090A (en) * 1988-01-25 1990-04-17 Warner-Lambert Company Substituted 2-aminbenzothiazoles and derivatives useful as cerebrovascular agents

Also Published As

Publication number Publication date
FR2649701A2 (fr) 1991-01-18
JPH02223569A (ja) 1990-09-05
NO173060B (no) 1993-07-12
NZ231793A (en) 1991-03-26
ES2054068T3 (es) 1994-08-01
IE894006L (en) 1990-06-15
HU203088B (en) 1991-05-28
JPH0733376B2 (ja) 1995-04-12
IL92710A0 (en) 1990-09-17
DK633689A (da) 1990-06-16
YU236989A (en) 1991-02-28
CZ708189A3 (en) 1995-06-14
CZ280107B6 (cs) 1995-10-18
PL161369B1 (en) 1993-06-30
DE68905585D1 (de) 1993-04-29
FI895981A0 (fi) 1989-12-14
DE68905585T2 (de) 1993-09-16
PT92604B (pt) 1995-09-12
EP0374040B1 (fr) 1993-03-24
FR2649701B2 (fr) 1991-11-22
CA2005590A1 (fr) 1990-06-15
IE62714B1 (en) 1995-02-22
SK278349B6 (en) 1997-01-08
DK633689D0 (da) 1989-12-14
AU4618989A (en) 1990-06-21
DK169967B1 (da) 1995-04-18
IL92710A (en) 1993-06-10
AU618432B2 (en) 1991-12-19
HUT53625A (en) 1990-11-28
FI93106B (fi) 1994-11-15
NO173060C (no) 1993-10-20
US5008280A (en) 1991-04-16
EP0374040A1 (fr) 1990-06-20
NO895030L (no) 1990-06-18
PL161336B1 (pl) 1993-06-30
RU2037489C1 (ru) 1995-06-19
YU47337B (sh) 1995-01-31
HU896612D0 (en) 1990-02-28
FI93106C (fi) 1995-02-27
NO895030D0 (no) 1989-12-14
SK708189A3 (en) 1997-01-08
GR3007788T3 (pt) 1993-08-31

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19950502

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19991130