PT91287A - Processo de preparacao de derivados do acido indazol-3-carboxilico e de composicoes farmaceuticas que os contem - Google Patents
Processo de preparacao de derivados do acido indazol-3-carboxilico e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT91287A PT91287A PT91287A PT9128789A PT91287A PT 91287 A PT91287 A PT 91287A PT 91287 A PT91287 A PT 91287A PT 9128789 A PT9128789 A PT 9128789A PT 91287 A PT91287 A PT 91287A
- Authority
- PT
- Portugal
- Prior art keywords
- indazol
- preparation
- carboxylic acid
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19190488 | 1988-07-29 | ||
| JP32298688 | 1988-12-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT91287A true PT91287A (pt) | 1990-02-08 |
| PT91287B PT91287B (pt) | 1995-03-01 |
Family
ID=26506977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT91287A PT91287B (pt) | 1988-07-29 | 1989-07-26 | Processo de preparacao de derivados do acido indazol-3-carboxilico e de composicoes farmaceuticas que os contem |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5017573A (pt) |
| EP (1) | EP0358903A3 (pt) |
| JP (2) | JPH0655738B2 (pt) |
| KR (1) | KR910002839A (pt) |
| AU (1) | AU621642B2 (pt) |
| DK (1) | DK374289A (pt) |
| FI (1) | FI893592A (pt) |
| HU (1) | HU204816B (pt) |
| NO (1) | NO173652C (pt) |
| NZ (1) | NZ230068A (pt) |
| PT (1) | PT91287B (pt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9214184D0 (en) * | 1992-07-03 | 1992-08-12 | Smithkline Beecham Plc | Pharmaceuticals |
| US5989586A (en) * | 1992-10-05 | 1999-11-23 | Cygnus, Inc. | Two-phase matrix for sustained release drug delivery device |
| US5654320A (en) * | 1995-03-16 | 1997-08-05 | Eli Lilly And Company | Indazolecarboxamides |
| IL117438A (en) * | 1995-03-16 | 2001-12-23 | Lilly Co Eli | Indazolecarboxamides, their preparation and pharmaceutical compositions containing them |
| WO1996038420A1 (fr) * | 1995-05-31 | 1996-12-05 | Nisshin Flour Milling Co., Ltd. | Derives de l'indazole a groupe amino monocyclique |
| EP0855397B1 (en) * | 1995-07-28 | 2001-05-09 | Dainippon Pharmaceutical Co., Ltd. | (r)-5-bromo-n-(1-ethyl-4-methylhexahydro-1h-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridine-carboxamide, process for producing the same and medicinal composition containing the same |
| US6046185A (en) * | 1996-07-11 | 2000-04-04 | Inflazyme Pharmaceuticals Ltd. | 6,7-oxygenated steroids and uses related thereto |
| US5914405A (en) * | 1997-10-07 | 1999-06-22 | Eli Lilly And Company | Process for preparing 3-substituted indazoles |
| GB9721139D0 (en) | 1997-10-07 | 1997-12-03 | Glaxo Group Ltd | Medicaments |
| US6069152A (en) * | 1997-10-07 | 2000-05-30 | Eli Lilly And Company | 5-HT4 agonists and antagonists |
| DE10041478A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| WO2003035005A2 (en) * | 2001-10-26 | 2003-05-01 | University Of Connecticut | Heteroindanes: a new class of potent cannabimimetic ligands |
| TW200533348A (en) * | 2004-02-18 | 2005-10-16 | Theravance Inc | Indazole-carboxamide compounds as 5-ht4 receptor agonists |
| US8309575B2 (en) | 2004-04-07 | 2012-11-13 | Theravance, Inc. | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
| TWI351282B (en) | 2004-04-07 | 2011-11-01 | Theravance Inc | Quinolinone-carboxamide compounds as 5-ht4 recepto |
| US7728006B2 (en) * | 2004-04-07 | 2010-06-01 | Theravance, Inc. | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
| TW200621237A (en) | 2004-11-01 | 2006-07-01 | Wyeth Corp | [(1-h-indazol-3-yl)methyl]phenols and (hydroxyphenyl)(1h-indazol-3-yl)methanones |
| ATE441646T1 (de) * | 2004-11-05 | 2009-09-15 | Theravance Inc | 5-ht4-rezeptoragonistenverbindungen |
| JP5042028B2 (ja) * | 2004-11-05 | 2012-10-03 | セラヴァンス， インコーポレーテッド | キノリノン−カルボキサミド化合物 |
| ATE469897T1 (de) * | 2004-12-22 | 2010-06-15 | Theravance Inc | Indazolcarbonsäureamidverbindungen |
| ES2523851T3 (es) * | 2005-03-02 | 2014-12-02 | Theravance Biopharma R&D Ip, Llc | Compuestos de quinolinona como agonistas de los receptores 5-HT4 |
| DK2432467T3 (en) | 2009-05-20 | 2018-04-16 | Inst Nat Sante Rech Med | SEROTONIN 5-HT3 RECEPTOR ANTAGONISTS FOR USE IN TREATMENT OF VESTIBULAR DAMAGE LESSONS |
| ES2432618T3 (es) | 2009-05-20 | 2013-12-04 | Inserm (Institut National De La Santé Et De La Recherche Medicale) | Antagonistas del receptor 5-HT3 de serotonina para usar en el tratamiento o prevención de una patología del oído interno con déficit vestibular |
| JOP20130213B1 (ar) | 2012-07-17 | 2021-08-17 | Takeda Pharmaceuticals Co | معارضات لمستقبلht3-5 |
| GB201511382D0 (en) | 2015-06-29 | 2015-08-12 | Imp Innovations Ltd | Novel compounds and their use in therapy |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1069122A (en) * | 1975-11-11 | 1980-01-01 | W.R. Grace And Co. | Preparation of dialkali metal hexahydropyrimidine-1, 3-diacetate and dialkalimetal 5-hydroxyhexahydropyrimidine-1, 3-diacetate |
| JPS5925785B2 (ja) * | 1976-01-01 | 1984-06-21 | 山之内製薬株式会社 | 新規なカルボン酸アミド誘導体 |
| US4207327A (en) * | 1977-08-19 | 1980-06-10 | A. H. Robins Company, Inc. | N-(4-Pyrazolidinyl)benzamides and their amino precursors |
| EP0049779B1 (en) * | 1980-09-18 | 1984-10-31 | Asahi Kasei Kogyo Kabushiki Kaisha | 3-aminoindazole derivatives and process for preparation thereof |
| CA1220141A (en) * | 1981-06-13 | 1987-04-07 | John R. Fozard | Treatment of migraine with tropyl benzoate derivatives |
| FI74707C (fi) * | 1982-06-29 | 1988-03-10 | Sandoz Ag | Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror. |
| JPS60123485A (ja) * | 1983-12-08 | 1985-07-02 | Yoshitomi Pharmaceut Ind Ltd | インド−ル−３−カルボキサミド誘導体 |
| EP0192935B1 (en) * | 1985-01-23 | 1991-02-27 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-(piperidinyl)-1h-indazoles a process for their preparation and their use as medicaments |
| GB8623142D0 (en) * | 1986-09-26 | 1986-10-29 | Beecham Group Plc | Compounds |
| EP0498466B1 (en) * | 1985-04-27 | 2002-07-24 | F. Hoffmann-La Roche Ag | Indazole-3-carboxamide and -3-carboxylic acid derivatives |
| GB8520616D0 (en) * | 1985-08-16 | 1985-09-25 | Beecham Group Plc | Compounds |
| GB8527052D0 (en) * | 1985-11-02 | 1985-12-04 | Beecham Group Plc | Compounds |
| EP0247266B1 (en) * | 1986-01-07 | 1993-03-10 | Beecham Group Plc | Indole derivatives having an azabicyclic side chain, process for their preparation, intermediates, and pharmaceutical compositions |
| EP0235878A3 (en) * | 1986-01-16 | 1989-06-14 | Beecham Group Plc | Novel compounds |
| DE3822792C2 (de) * | 1987-07-11 | 1997-11-27 | Sandoz Ag | Neue Verwendung von 5HT¶3¶-Antagonisten |
| JPH01117860A (ja) * | 1987-10-30 | 1989-05-10 | Dainippon Pharmaceut Co Ltd | 安息香酸アミド誘導体 |
| EP0410509A1 (en) * | 1989-07-25 | 1991-01-30 | Duphar International Research B.V | New substituted 1H-indazole-3-carboxamides |
| US4954503A (en) * | 1989-09-11 | 1990-09-04 | Hoechst-Roussel Pharmaceuticals, Inc. | 3-(1-substituted-4-piperazinyl)-1H-indazoles |
-
1989
- 1989-07-25 US US07/384,766 patent/US5017573A/en not_active Expired - Fee Related
- 1989-07-25 NZ NZ230068A patent/NZ230068A/en unknown
- 1989-07-26 PT PT91287A patent/PT91287B/pt not_active IP Right Cessation
- 1989-07-26 EP EP19890113776 patent/EP0358903A3/en not_active Withdrawn
- 1989-07-27 FI FI893592A patent/FI893592A/fi not_active Application Discontinuation
- 1989-07-27 HU HU893824A patent/HU204816B/hu not_active IP Right Cessation
- 1989-07-27 JP JP1196351A patent/JPH0655738B2/ja not_active Expired - Lifetime
- 1989-07-27 KR KR1019890010658A patent/KR910002839A/ko not_active Application Discontinuation
- 1989-07-28 NO NO893078A patent/NO173652C/no unknown
- 1989-07-28 AU AU39103/89A patent/AU621642B2/en not_active Ceased
- 1989-07-28 DK DK374289A patent/DK374289A/da not_active Application Discontinuation
-
1992
- 1992-01-31 JP JP4046294A patent/JP2898139B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0358903A3 (en) | 1992-03-04 |
| HUT52093A (en) | 1990-06-28 |
| US5017573A (en) | 1991-05-21 |
| FI893592A0 (fi) | 1989-07-27 |
| DK374289D0 (da) | 1989-07-28 |
| FI893592A (fi) | 1990-01-30 |
| PT91287B (pt) | 1995-03-01 |
| JPH0592959A (ja) | 1993-04-16 |
| NO893078L (no) | 1990-01-30 |
| JPH02256670A (ja) | 1990-10-17 |
| DK374289A (da) | 1990-01-30 |
| NO173652B (no) | 1993-10-04 |
| JP2898139B2 (ja) | 1999-05-31 |
| AU3910389A (en) | 1990-02-01 |
| JPH0655738B2 (ja) | 1994-07-27 |
| AU621642B2 (en) | 1992-03-19 |
| NZ230068A (en) | 1991-07-26 |
| NO173652C (no) | 1994-01-12 |
| HU204816B (en) | 1992-02-28 |
| KR910002839A (ko) | 1991-02-26 |
| NO893078D0 (no) | 1989-07-28 |
| EP0358903A2 (en) | 1990-03-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19940812 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19960229 |