PT89793A - Processo de preparacao de derivados de quinolina substituidos e de composicoes farmaceuticas que os contem - Google Patents
Processo de preparacao de derivados de quinolina substituidos e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT89793A PT89793A PT89793A PT8979389A PT89793A PT 89793 A PT89793 A PT 89793A PT 89793 A PT89793 A PT 89793A PT 8979389 A PT8979389 A PT 8979389A PT 89793 A PT89793 A PT 89793A
- Authority
- PT
- Portugal
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- quinoline derivatives
- substituted quinoline
- preparing substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888804448A GB8804448D0 (en) | 1988-02-25 | 1988-02-25 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT89793A true PT89793A (pt) | 1989-10-04 |
Family
ID=10632380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT89793A PT89793A (pt) | 1988-02-25 | 1989-02-22 | Processo de preparacao de derivados de quinolina substituidos e de composicoes farmaceuticas que os contem |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4935431A (pt) |
| EP (1) | EP0334491A1 (pt) |
| JP (1) | JPH02503317A (pt) |
| KR (1) | KR900700485A (pt) |
| CN (1) | CN1035508A (pt) |
| AU (1) | AU3181689A (pt) |
| DK (1) | DK528689A (pt) |
| FI (1) | FI895047A0 (pt) |
| GB (1) | GB8804448D0 (pt) |
| HU (1) | HU891461D0 (pt) |
| IL (1) | IL89347A0 (pt) |
| NO (1) | NO894228L (pt) |
| PT (1) | PT89793A (pt) |
| WO (1) | WO1989008112A1 (pt) |
| ZA (1) | ZA891440B (pt) |
| ZW (1) | ZW2089A1 (pt) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2011086A1 (en) * | 1989-03-17 | 1990-09-17 | Karl-Heinz Geiss | 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom |
| NZ233641A (en) * | 1989-05-16 | 1992-07-28 | Merrell Dow Pharma | Quinoline and thienopyridine derivatives and excitatory amino acid antagonistic pharmaceutical compositions |
| US5026700A (en) * | 1989-05-16 | 1991-06-25 | Merrell Dow Pharmaceuticals | Certain quinolines and thienopyridines as excitatory amino acid antagonists |
| GB8918265D0 (en) * | 1989-08-10 | 1989-09-20 | Smithkline Beckman Intercredit | Compounds |
| IE68593B1 (en) * | 1989-12-06 | 1996-06-26 | Sanofi Sa | Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them |
| GB9010296D0 (en) * | 1990-05-08 | 1990-06-27 | Beecham Group Plc | Novel compounds |
| US5556863A (en) * | 1993-06-11 | 1996-09-17 | Astra Aktiebolag | Compound for gastric acid secretion inhibition |
| IS4164A (is) * | 1993-06-11 | 1994-12-12 | Ab Astra | Efnasambönd sem hindra flæði magasýru |
| KR0169813B1 (ko) * | 1995-07-12 | 1999-01-15 | 김종인 | 4-아미노-3-아실나프티리딘 유도체 |
| WO1999043681A1 (en) | 1998-02-26 | 1999-09-02 | Neurogen Corporation | 4-(4-piperidylmethylamino) substituted heteroaryl fused pyridines: gaba brain receptor ligands |
| US6232320B1 (en) * | 1998-06-04 | 2001-05-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
| GB0420722D0 (en) | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
| RU2388761C2 (ru) * | 2004-12-17 | 2010-05-10 | Ф. Хоффманн-Ля Рош Аг | Производные тиенопиридина в качестве аллостерических энхансеров гамк-в |
| MX2007014929A (es) | 2005-06-02 | 2008-02-15 | Hoffmann La Roche | 3-metansulfonilquinolinas como mejoradores de gaba-b. |
| AR059898A1 (es) | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2 |
| TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
| TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
| MX2010002537A (es) | 2007-09-14 | 2010-08-10 | Ortho Mcneil Janssen Pharm | 4-fenil-1h-piridin-2-onas 1,3-disubstituidas. |
| CA2697399C (en) | 2007-09-14 | 2016-01-19 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | 1,3-disubstituted 4-(aryl-x-phenyl)-1h-pyridin-2-ones |
| NZ584145A (en) | 2007-09-14 | 2012-03-30 | Ortho Mcneil Janssen Pharm | 1',3'-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2h, 1'h-[1,4'] bipyridinyl-2'-ones |
| EP2220083B1 (en) | 2007-11-14 | 2017-07-19 | Janssen Pharmaceuticals, Inc. | Imidazo[1,2-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| EP2574610A1 (en) * | 2007-11-15 | 2013-04-03 | Gilead Sciences, Inc. | Inhibitors of human immonodeficiency virus replication |
| JP5547194B2 (ja) | 2008-09-02 | 2014-07-09 | ジャンセン ファーマシューティカルズ， インコーポレイテッド． | 代謝型グルタミン酸受容体の調節因子としての３−アザビシクロ［３．１．０］ヘキシル誘導体 |
| MX2011003691A (es) | 2008-10-16 | 2011-09-06 | Ortho Mcneil Janssen Pharm | Derivados de indol y benzomorfolina como moduladores de los receptores de glutamato metabotropico. |
| ES2401691T3 (es) | 2008-11-28 | 2013-04-23 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Derivados de indol y de benzoxacina como moduladores de los receptores metabotrópicos de glutamato |
| MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| CN102439008B (zh) | 2009-05-12 | 2015-04-29 | 杨森制药有限公司 | 1,2,4-三唑并[4,3-a]吡啶衍生物及其用于治疗或预防神经和精神病症的用途 |
| NZ596053A (en) | 2009-05-12 | 2013-05-31 | Janssen Pharmaceuticals Inc | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| CN103261195B (zh) | 2010-11-08 | 2015-09-02 | 杨森制药公司 | 1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途 |
| WO2012062750A1 (en) | 2010-11-08 | 2012-05-18 | Janssen Pharmaceuticals, Inc. | 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS |
| CA2815002C (en) | 2010-11-08 | 2019-10-22 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
| JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
| KR20220049612A (ko) | 2014-01-21 | 2022-04-21 | 얀센 파마슈티카 엔.브이. | 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도 |
| ES2748633T3 (es) | 2014-01-21 | 2020-03-17 | Janssen Pharmaceutica Nv | Combinaciones que comprenden moduladores alostéricos positivos del receptor glutamatérgico metabotrópico de subtipo 2 y su uso |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2652398A (en) * | 1949-11-17 | 1953-09-15 | Endo Products Inc | N-substituted-2-amino (methyl) quinolines |
| US3470186A (en) * | 1967-06-02 | 1969-09-30 | American Cyanamid Co | Substituted 4-anilino-3-quinolinecarboxylic acids and esters |
| CA942748A (en) * | 1970-09-18 | 1974-02-26 | Venkatachala L. Narayanan | 1-aziridinylcarbonyl substituted-3-quinolinecarboxylic acid compounds |
| US4343804A (en) * | 1979-03-26 | 1982-08-10 | A. H. Robins Company, Inc. | 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds |
| EP0126970A3 (en) * | 1983-04-27 | 1985-11-06 | Beecham Group Plc | Anxiolytic and anti-depressant thienopyridine derivatives |
| GB8621425D0 (en) * | 1986-09-05 | 1986-10-15 | Smith Kline French Lab | Compounds |
-
1988
- 1988-02-25 GB GB888804448A patent/GB8804448D0/en active Pending
-
1989
- 1989-02-20 IL IL89347A patent/IL89347A0/xx unknown
- 1989-02-20 HU HU891461A patent/HU891461D0/hu unknown
- 1989-02-20 WO PCT/EP1989/000174 patent/WO1989008112A1/en active Application Filing
- 1989-02-20 AU AU31816/89A patent/AU3181689A/en not_active Abandoned
- 1989-02-20 JP JP1502450A patent/JPH02503317A/ja active Pending
- 1989-02-20 ZW ZW20/89A patent/ZW2089A1/xx unknown
- 1989-02-22 PT PT89793A patent/PT89793A/pt not_active Application Discontinuation
- 1989-02-23 US US07/314,617 patent/US4935431A/en not_active Expired - Fee Related
- 1989-02-23 EP EP89301801A patent/EP0334491A1/en not_active Withdrawn
- 1989-02-24 ZA ZA891440A patent/ZA891440B/xx unknown
- 1989-02-24 CN CN89100950A patent/CN1035508A/zh active Pending
- 1989-10-24 DK DK528689A patent/DK528689A/da not_active Application Discontinuation
- 1989-10-24 NO NO89894228A patent/NO894228L/no unknown
- 1989-10-24 KR KR1019890701953A patent/KR900700485A/ko not_active Application Discontinuation
- 1989-10-24 FI FI895047A patent/FI895047A0/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US4935431A (en) | 1990-06-19 |
| NO894228D0 (no) | 1989-10-24 |
| ZW2089A1 (en) | 1989-09-13 |
| CN1035508A (zh) | 1989-09-13 |
| ZA891440B (en) | 1990-10-31 |
| WO1989008112A1 (en) | 1989-09-08 |
| EP0334491A1 (en) | 1989-09-27 |
| GB8804448D0 (en) | 1988-03-23 |
| FI895047A0 (fi) | 1989-10-24 |
| DK528689D0 (da) | 1989-10-24 |
| HU891461D0 (en) | 1990-01-28 |
| DK528689A (da) | 1989-10-24 |
| KR900700485A (ko) | 1990-08-13 |
| AU3181689A (en) | 1989-09-22 |
| JPH02503317A (ja) | 1990-10-11 |
| NO894228L (no) | 1989-10-24 |
| IL89347A0 (en) | 1989-12-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT89793A (pt) | Processo de preparacao de derivados de quinolina substituidos e de composicoes farmaceuticas que os contem | |
| PT93241A (pt) | Processo de preparacao de derivados de piperidina e de composicoes farmaceuticas que os contem | |
| PT89009A (pt) | Processo para a preparacao de novos derivados de fluorocitidina e composicoes farmaceuticas que os contem | |
| PT88993A (pt) | Processo de preparacao de compostos azaciclicos e de composicoes farmaceuticas que os contem | |
| PT92497A (pt) | Processo para a preparacao de derivados de ureia de dipeptideos inibidores de enzimas, e de composicoes farmaceuticas que os contem | |
| PT87913A (pt) | Processo para a preparacao de derivados de benzopirano e de composicoes farmaceuticas que os contem | |
| PT89328A (pt) | Processo para a preparacao de novos derivados da adenosina e de composicoes farmaceuticas que os contem | |
| PT87201A (pt) | Processo para a preparacao de novos derivados de cefalosporina 3,7-substituida e de composicoes farmaceuticas que os contem | |
| PT91287A (pt) | Processo de preparacao de derivados do acido indazol-3-carboxilico e de composicoes farmaceuticas que os contem | |
| PT88203A (pt) | Processo para a preparacao de quinolonas e de composicoes farmaceuticas que as contem | |
| PT97437A (pt) | Processo de preparacao de derivados de hidrato de carbono e de composicoes farmaceuticas que os contem | |
| PT89405B (pt) | Processo para a preparacao de derivados de isoquinolina e de composicoes farmaceuticas que os contem | |
| PT97114A (pt) | Processo para a preparacao de derivados de hidantoina e de composicoes farmaceuticas que os contem | |
| PT84681B (pt) | Processo para a preparacao de carboxamidas heterociclicas e de composicoes farmaceuticas que as contem | |
| PT83998B (pt) | Processo de preparacao de novos derivados azaciclicos e de composicoes farmaceuticas que os contem | |
| PT84187B (pt) | Processo para a preparacao de novos derivados da isoquinolina e de composicoes farmaceuticas que os contem | |
| PT89792A (pt) | Processo de preparacao de derivados da quinolina substituidos e de composicoes farmaceuticas que os contem | |
| PT89790A (pt) | Processo de preparacao de derivados da quinolina substituidos e de composicoes farmaceuticas que os contem | |
| PT89145A (pt) | Processo para a preparacao de derivados da manumicina e de composicoes farmaceuticas que os contem | |
| PT90864A (pt) | Processo para a preparacao de derivados de cromano e de composicoes farmaceuticas que os contem | |
| PT82319B (pt) | Processo de preparacao de derivados de indeno e de naftaleno e de composicoes farmceuticas que os contem | |
| PT88351A (pt) | Processo para a preparacao de derivados de isoxazol-beta-carbolina e de composicoes farmaceuticas que os contem | |
| PT91979A (pt) | Processo para a preparacao de derivados de cromano e de composicoes farmaceuticas que os contem | |
| PT87115A (pt) | Processo para a preparacao de derivados da dihidropiridazinona e de composicoes farmaceuticas que os contem | |
| PT87090A (pt) | Processo para a preparacao de derivados de imidazopiridinas e de composicoes farmaceuticas que os contem |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC3A | Refusal |
Effective date: 19940721 |