SK64399A3 - Multivalent salts of pyridostigmine and related compounds - Google Patents

Multivalent salts of pyridostigmine and related compounds Download PDF

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Publication number
SK64399A3
SK64399A3 SK643-99A SK64399A SK64399A3 SK 64399 A3 SK64399 A3 SK 64399A3 SK 64399 A SK64399 A SK 64399A SK 64399 A3 SK64399 A3 SK 64399A3
Authority
SK
Slovakia
Prior art keywords
anion
compound
compound according
anions
patient
Prior art date
Application number
SK643-99A
Other languages
English (en)
Slovak (sk)
Inventor
Colin D Granger
Robert Orr
Kandasamy Ramasamy
Original Assignee
Icn Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icn Pharmaceuticals filed Critical Icn Pharmaceuticals
Publication of SK64399A3 publication Critical patent/SK64399A3/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/34One oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/40Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/42Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
SK643-99A 1996-11-19 1997-11-10 Multivalent salts of pyridostigmine and related compounds SK64399A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3118696P 1996-11-19 1996-11-19
PCT/US1997/020509 WO1998022458A1 (en) 1996-11-19 1997-11-10 Multivalent salts of pyridostigmine and related compounds

Publications (1)

Publication Number Publication Date
SK64399A3 true SK64399A3 (en) 2000-05-16

Family

ID=21858083

Family Applications (1)

Application Number Title Priority Date Filing Date
SK643-99A SK64399A3 (en) 1996-11-19 1997-11-10 Multivalent salts of pyridostigmine and related compounds

Country Status (17)

Country Link
US (1) US6211201B1 (de)
EP (1) EP0941224A4 (de)
JP (1) JP2001505561A (de)
KR (1) KR20000069028A (de)
CN (1) CN1237969A (de)
AU (1) AU717740B2 (de)
BR (1) BR9713112A (de)
CA (1) CA2271786A1 (de)
CZ (1) CZ172799A3 (de)
HU (1) HUP9904040A3 (de)
IL (1) IL129619A0 (de)
NO (1) NO992384L (de)
NZ (1) NZ335419A (de)
PL (1) PL333414A1 (de)
SI (1) SI20018A (de)
SK (1) SK64399A3 (de)
WO (1) WO1998022458A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1390032A4 (de) * 2001-05-11 2004-12-29 Marvin B Bacaner Neue, mit erleichternden anionen gekuppelte quaternäre ammoniumzusammensetzungen und ihre verwendung in kits sowie ihre verwendung bei der prävention und behandlung bestimmter erkrankungen
US7176201B2 (en) * 2002-10-07 2007-02-13 The Regents Of The University Of California Modulation of anxiety through blockade of anandamide hydrolysis
US20050182252A1 (en) 2004-02-13 2005-08-18 Reddy K. R. Novel 2'-C-methyl nucleoside derivatives
US10449210B2 (en) 2014-02-13 2019-10-22 Ligand Pharmaceuticals Inc. Prodrug compounds and their uses
EP3164136A4 (de) 2014-07-02 2018-04-04 Ligand Pharmaceuticals, Inc. Prodrug-verbindungen und verwendungen davon
CN107854428A (zh) * 2016-12-20 2018-03-30 成都医学院 一种溴吡斯的明糖浆剂及其制备方法
CA3087932A1 (en) 2018-01-09 2019-07-18 Ligand Pharmaceuticals, Inc. Acetal compounds and therapeutic uses thereof
CN113277961B (zh) * 2021-04-09 2023-05-09 深圳市新浩瑞医药科技有限公司 一种溴新斯的明的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4692530A (en) * 1967-03-07 1987-09-08 The United States Of America As Represented By The Secretary Of The Army Chemical agents
US4686293A (en) * 1967-05-29 1987-08-11 The United States Of America As Represented By The Secretary Of The Army Chemical agents
US4672120A (en) * 1967-07-03 1987-06-09 The United States Of America As Represented By The Secretary Of The Army Chemical agents
US4246416A (en) * 1967-12-01 1981-01-20 The United States Of America As Represented By The Secretary Of The Army Chemical agents
US4677222A (en) * 1968-01-22 1987-06-30 The United States Of America As Represented By The Secretary Of The Army Ketobenzylcarbamates
US5534623A (en) * 1993-01-21 1996-07-09 Du Pont (Uk) Limited Process for preparing a polyunsaturated diazonium compounds

Also Published As

Publication number Publication date
EP0941224A4 (de) 2000-01-12
HUP9904040A2 (hu) 2000-05-28
NZ335419A (en) 2000-05-26
SI20018A (sl) 2000-02-29
CZ172799A3 (cs) 1999-10-13
AU717740B2 (en) 2000-03-30
PL333414A1 (en) 1999-12-06
KR20000069028A (ko) 2000-11-25
CA2271786A1 (en) 1998-05-28
JP2001505561A (ja) 2001-04-24
BR9713112A (pt) 2000-04-11
HUP9904040A3 (en) 2000-09-28
AU6236798A (en) 1998-06-10
WO1998022458A1 (en) 1998-05-28
NO992384D0 (no) 1999-05-18
EP0941224A1 (de) 1999-09-15
CN1237969A (zh) 1999-12-08
US6211201B1 (en) 2001-04-03
IL129619A0 (en) 2000-02-29
NO992384L (no) 1999-07-16

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