SK6182003A3 - Crystalline and solvated forms of ondansetrone hydrochloride and preparation thereof - Google Patents

Crystalline and solvated forms of ondansetrone hydrochloride and preparation thereof Download PDF

Info

Publication number
SK6182003A3
SK6182003A3 SK618-2003A SK6182003A SK6182003A3 SK 6182003 A3 SK6182003 A3 SK 6182003A3 SK 6182003 A SK6182003 A SK 6182003A SK 6182003 A3 SK6182003 A3 SK 6182003A3
Authority
SK
Slovakia
Prior art keywords
ondansetron
ondansetron hydrochloride
ethanol
hydrochloride form
anhydrous
Prior art date
Application number
SK618-2003A
Other languages
English (en)
Slovak (sk)
Inventor
Rami Lidor-Hadas
Judith Aronhime
Revital Lifshitz
Shlomit Weizel
Valerie Niddam
Valerie Maymon
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of SK6182003A3 publication Critical patent/SK6182003A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Steroid Compounds (AREA)
SK618-2003A 2000-10-30 2001-10-30 Crystalline and solvated forms of ondansetrone hydrochloride and preparation thereof SK6182003A3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24428300P 2000-10-30 2000-10-30
US25381900P 2000-11-29 2000-11-29
US26553901P 2001-01-31 2001-01-31
PCT/US2001/048720 WO2002036558A2 (en) 2000-10-30 2001-10-30 Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation

Publications (1)

Publication Number Publication Date
SK6182003A3 true SK6182003A3 (en) 2004-03-02

Family

ID=27399743

Family Applications (1)

Application Number Title Priority Date Filing Date
SK618-2003A SK6182003A3 (en) 2000-10-30 2001-10-30 Crystalline and solvated forms of ondansetrone hydrochloride and preparation thereof

Country Status (20)

Country Link
US (1) US20020107275A1 (es)
EP (1) EP1339707A2 (es)
JP (1) JP2004525083A (es)
KR (1) KR20030042038A (es)
CN (1) CN1498216A (es)
AU (1) AU2002230935A1 (es)
CA (1) CA2426026A1 (es)
CZ (1) CZ20031397A3 (es)
DE (1) DE01991193T1 (es)
ES (1) ES2204358T1 (es)
HR (1) HRP20030432A2 (es)
HU (1) HUP0401239A2 (es)
IL (1) IL155644A0 (es)
IS (1) IS6797A (es)
MX (1) MXPA03003761A (es)
NO (1) NO20031928L (es)
PL (1) PL366150A1 (es)
SK (1) SK6182003A3 (es)
WO (1) WO2002036558A2 (es)
YU (1) YU32003A (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE02703115T1 (de) * 2001-01-11 2004-10-21 Teva Pharmaceutical Industries Ltd. Verbessertes verfahren zur herstellung von reinem ondansetronhydrochlorid-dihydrat
DK1499623T3 (da) 2002-04-29 2007-10-08 Teva Gyogyszerg Ar Zartkoeruee Fremgangsmåde til fremstilling af 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-on
FI6164U1 (fi) * 2003-01-09 2004-03-15 Synthon Bv Ondansetronmuotoja
EP1828141A4 (en) * 2004-10-26 2009-04-01 Ipca Lab Ltd STAINING METHOD FOR PREPARING THE ANTIEMETIC 1,2,3,9-TETRAHYDRO-9-METHYL-3 - [(2-METHYL) -1H-IMIDAZOLE-1-YL) METHYL] -4H-CARBAZOLE-4-ON
KR20140088230A (ko) * 2006-01-27 2014-07-09 앱탈리스 파마테크, 인코포레이티드 약 염기성 약물과 유기산을 포함하는 약물 전달 시스템
WO2007090082A2 (en) * 2006-01-27 2007-08-09 Eurand, Inc. Drug delivery systems comprising weakly basic selective serotonin 5-ht3 blocking agent and organic acids
US20100105724A1 (en) * 2006-12-07 2010-04-29 Helsinn Healthcare Sa Crystalline and amorphous forms of palonosetron hydrochloride
US8133506B2 (en) 2008-03-12 2012-03-13 Aptalis Pharmatech, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
CN102190594A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀氯化氢水合物及其制备方法
CN102190595A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀溴化氢水合物及其制备方法
CR20200220A (es) 2013-11-15 2020-11-18 Akebia Therapeutics Inc FORMAS SÓLIDAS DE ÁCIDO {[5-(3-CLOROFENIL)-3-HIDROXIPIRIDIN-2-CARBONIL]AMINO}ACÉTICO, COMPOSICIONES, Y USOS DE LAS MISMAS (Divisional 2016-0222)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695578A (en) * 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
EP0405617A3 (en) * 1985-03-14 1992-11-25 Beecham Group P.L.C. Medicaments for the treatment of anxiety
GB8518742D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8518741D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8630071D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
GB8816187D0 (en) * 1988-07-07 1988-08-10 Glaxo Group Ltd Medicaments
US5344658A (en) * 1989-06-28 1994-09-06 Glaxo Group Limited Process and composition using ondansetron
CA2112487C (en) * 1991-06-26 2003-04-15 James W. Young Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron
CA2106642C (en) * 1992-10-14 2005-08-16 Peter Bod Carbazolone derivatives and process for preparing the same
GB9423588D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
GB9423511D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
CN1045437C (zh) * 1994-12-29 1999-10-06 中国科学院上海有机化学研究所 恩丹西酮及其生理盐的合成
EP1207160A1 (en) * 2000-11-20 2002-05-22 Hanmi Pharm. Co., Ltd. Process for the preparation of 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)-methyl)-4H-carbazol-4-one
DK1499623T3 (da) * 2002-04-29 2007-10-08 Teva Gyogyszerg Ar Zartkoeruee Fremgangsmåde til fremstilling af 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-on
CN1665803A (zh) * 2002-04-30 2005-09-07 特瓦药厂有限公司 新晶形的昂丹司琼及其制备方法、含有该新晶形的药物组合物以及用其治疗恶心的方法

Also Published As

Publication number Publication date
WO2002036558A3 (en) 2003-02-06
CN1498216A (zh) 2004-05-19
PL366150A1 (en) 2005-01-24
WO2002036558A2 (en) 2002-05-10
CZ20031397A3 (cs) 2003-11-12
HUP0401239A2 (hu) 2004-12-28
IL155644A0 (en) 2003-11-23
JP2004525083A (ja) 2004-08-19
YU32003A (sh) 2006-05-25
NO20031928L (no) 2003-06-27
HRP20030432A2 (en) 2004-06-30
MXPA03003761A (es) 2003-07-28
DE01991193T1 (de) 2004-07-08
KR20030042038A (ko) 2003-05-27
CA2426026A1 (en) 2002-05-10
AU2002230935A1 (en) 2002-05-15
EP1339707A2 (en) 2003-09-03
NO20031928D0 (no) 2003-04-29
IS6797A (is) 2003-04-29
US20020107275A1 (en) 2002-08-08
ES2204358T1 (es) 2004-05-01

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