SK54595A3 - Heterocyclic compounds, pharmaceutical preparations containing them and method of their preparation - Google Patents

Heterocyclic compounds, pharmaceutical preparations containing them and method of their preparation Download PDF

Info

Publication number
SK54595A3
SK54595A3 SK545-95A SK54595A SK54595A3 SK 54595 A3 SK54595 A3 SK 54595A3 SK 54595 A SK54595 A SK 54595A SK 54595 A3 SK54595 A3 SK 54595A3
Authority
SK
Slovakia
Prior art keywords
isoquinoline
dimethoxy
hydrogen
formula
pharmaceutically acceptable
Prior art date
Application number
SK545-95A
Other languages
English (en)
Slovak (sk)
Inventor
Gyula Balogh
Imre Doman
Gabor Blasko
Gyula Simig
Erszebet K Kovacs
Istvan Gyertyan
Andras Egyed
Istvan Gacsalyi
Andras Bilkei-Gorzo
Katalin Pallagi
Katalin Szemerudi
Klara D Kazo
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of SK54595A3 publication Critical patent/SK54595A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK545-95A 1994-05-03 1995-04-27 Heterocyclic compounds, pharmaceutical preparations containing them and method of their preparation SK54595A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9401281A HUT71407A (en) 1994-05-03 1994-05-03 Heterocyclic compounds, pharmaceutical compositions containing them, and process for producing the active components

Publications (1)

Publication Number Publication Date
SK54595A3 true SK54595A3 (en) 1995-11-08

Family

ID=10985144

Family Applications (1)

Application Number Title Priority Date Filing Date
SK545-95A SK54595A3 (en) 1994-05-03 1995-04-27 Heterocyclic compounds, pharmaceutical preparations containing them and method of their preparation

Country Status (14)

Country Link
US (1) US5889018A (xx)
EP (1) EP0680953A1 (xx)
JP (1) JPH0848670A (xx)
KR (1) KR950032131A (xx)
CA (1) CA2148412A1 (xx)
CZ (1) CZ109195A3 (xx)
FR (1) FR2719586B1 (xx)
HR (1) HRP950267A2 (xx)
HU (1) HUT71407A (xx)
IT (1) IT1273613B (xx)
PL (1) PL308417A1 (xx)
RU (1) RU95106947A (xx)
SK (1) SK54595A3 (xx)
YU (1) YU27895A (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001009101A1 (en) * 1999-07-29 2001-02-08 EGIS Gyógyszergyár Rt. Isoquinoline derivatives, pharmaceutical compositions containing the same, and a process for the preparation of the active substance
CN107434781A (zh) * 2016-05-27 2017-12-05 河南工业大学 一种1-烯基-异喹啉衍生物的制备方法及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE576532C (de) * 1930-11-28 1933-05-17 C H Boehringer Sohn A G Verfahren zur Darstellung von Isochinolinabkoemmlingen
DE1902402A1 (de) * 1968-05-21 1969-11-27 Dresden Arzneimittel Verfahren zur Herstellung von 1-substituierten 6.7-Dimethoxy-isochinolinen
JPS62145049A (ja) * 1985-12-18 1987-06-29 Mitsubishi Chem Ind Ltd アミノスチリル化合物及びそれを有効成分とするロイコトリエンきつ抗剤

Also Published As

Publication number Publication date
RU95106947A (ru) 1997-03-10
HRP950267A2 (en) 1997-08-31
KR950032131A (ko) 1995-12-20
IT1273613B (it) 1997-07-08
HU9401281D0 (en) 1994-08-29
YU27895A (sh) 1998-07-10
CZ109195A3 (en) 1996-02-14
ITMI950880A0 (it) 1995-05-03
JPH0848670A (ja) 1996-02-20
PL308417A1 (en) 1995-11-13
FR2719586A1 (fr) 1995-11-10
ITMI950880A1 (it) 1996-11-03
FR2719586B1 (fr) 1998-01-02
EP0680953A1 (en) 1995-11-08
US5889018A (en) 1999-03-30
CA2148412A1 (en) 1995-11-04
HUT71407A (en) 1995-11-28

Similar Documents

Publication Publication Date Title
US6025367A (en) Sulfonamide derivatives as 5HT7 receptor antagonists
AU2001260081B2 (en) Benzophenones as inhibitors of il-1beta and tnf-alpha
EP2308848A1 (en) Quinoline-derived amide modulators of vanilloid VR1 receptor
US5602152A (en) Benzoxepines
JP2008502628A (ja) ピリダジン−３（２ｈ）−オン誘導体およびｐｄｅ４の阻害剤としてのそれらの使用
PL188908B1 (pl) Nowe pochodne benzimidazolu i ich zastosowanie dowytwarzania leków do leczenia stanów alergicznych
CA2148053A1 (en) Non-peptidyl tachykinin receptor antagonists
CZ291040B6 (cs) Trisubstituované fenylové deriváty a farmaceutický prostředek s jejich obsahem
JP2009538358A (ja) 脂肪酸アミド加水分解酵素のオキサゾリルピペリジン・モジュレーター
CA2659952A1 (en) 8-hydroxyquinoline compounds and methods thereof
AU782993B2 (en) 1,2-diaryl benzimidazoles for treating illnesses associated with a microglia activation
JP5892550B2 (ja) 縮合イミダゾール誘導体
PL119501B1 (en) Process for manufacturing novel,condensed pyrimidine derivatives pirimidina
US5670522A (en) Dopamine receptor subtype ligands
US7345075B2 (en) 1,2 diarylbenzimidazoles and their pharmaceutical use
PT754682E (pt) Derivado de aminostilbazol e medicamento
AU681601B2 (en) O-aryl ethers of morphinans
HU195211B (en) Process for producing 5-alkyl-1-phenyl-2-(piperazinoalkyl)-pyrazolin-3-one derivatives and pharmaceutical preparations comprising the same
Apelt et al. Search for histamine H3 receptor antagonists with combined inhibitory potency at N τ-methyltransferase: ether derivatives
CZ199992A3 (en) 2-(piperidin-1-yl)ethanol derivatives, process of their preparation and pharmaceutical compositions containing said derivatives
KR100248643B1 (ko) 아릴 및 헤테로아릴 알콕시나프탈렌 유도체
JPS6322049A (ja) 不可逆的ド−パミン−β−ヒドロキシラ−ゼ抑制剤
SK54595A3 (en) Heterocyclic compounds, pharmaceutical preparations containing them and method of their preparation
US4588725A (en) 2-piperazinyl-quinazoline derivatives and pharmaceutical compositions containing them
JPH03120271A (ja) 抗虚血活性を有するフェニルアルキルアミン誘導体