SK4232002A3 - Fibrinolytically active polypeptide - Google Patents
Fibrinolytically active polypeptide Download PDFInfo
- Publication number
- SK4232002A3 SK4232002A3 SK423-2002A SK4232002A SK4232002A3 SK 4232002 A3 SK4232002 A3 SK 4232002A3 SK 4232002 A SK4232002 A SK 4232002A SK 4232002 A3 SK4232002 A3 SK 4232002A3
- Authority
- SK
- Slovakia
- Prior art keywords
- leu
- ser
- ala
- asp
- thr
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
- C12N9/6418—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals from snakes
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Marine Sciences & Fisheries (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/411,329 US6261820B1 (en) | 1999-10-01 | 1999-10-01 | Fibronolytically active polypeptide |
PCT/US2000/027029 WO2001025445A1 (en) | 1999-10-01 | 2000-09-29 | Fibrinolytically active polypeptide |
Publications (1)
Publication Number | Publication Date |
---|---|
SK4232002A3 true SK4232002A3 (en) | 2003-09-11 |
Family
ID=23628486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK423-2002A SK4232002A3 (en) | 1999-10-01 | 2000-09-29 | Fibrinolytically active polypeptide |
Country Status (29)
Country | Link |
---|---|
US (4) | US6261820B1 (ru) |
EP (2) | EP1224298B1 (ru) |
JP (1) | JP2003511034A (ru) |
KR (2) | KR100700753B1 (ru) |
CN (2) | CN100357430C (ru) |
AT (1) | ATE292180T1 (ru) |
AU (1) | AU767827B2 (ru) |
BG (1) | BG106577A (ru) |
BR (1) | BR0014414A (ru) |
CA (1) | CA2386185A1 (ru) |
CZ (1) | CZ298502B6 (ru) |
DE (1) | DE60019147T2 (ru) |
DK (1) | DK1224298T3 (ru) |
EA (2) | EA005944B1 (ru) |
ES (1) | ES2240167T3 (ru) |
HK (1) | HK1049351B (ru) |
HU (1) | HUP0202650A3 (ru) |
IL (1) | IL148787A0 (ru) |
MX (1) | MXPA02003126A (ru) |
NO (1) | NO20021501L (ru) |
NZ (1) | NZ517951A (ru) |
PL (1) | PL355017A1 (ru) |
PT (1) | PT1224298E (ru) |
RS (1) | RS20060033A (ru) |
SG (1) | SG127720A1 (ru) |
SK (1) | SK4232002A3 (ru) |
WO (1) | WO2001025445A1 (ru) |
YU (2) | YU59604A (ru) |
ZA (1) | ZA200202206B (ru) |
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US6455269B1 (en) * | 1999-12-17 | 2002-09-24 | Amgen, Inc. | Method for localized administration of fibrinolytic metalloproteinases |
US7033776B2 (en) | 1999-12-17 | 2006-04-25 | Amgen Inc. | Method for treatment of indwelling catheter occlusion using fibrinolytic metalloproteinases |
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AU2003215119B2 (en) * | 2002-02-11 | 2008-11-20 | Gold-T Tech, Inc. | Method for preventing thrombus formation |
US7016409B2 (en) * | 2003-11-12 | 2006-03-21 | Sony Corporation | Apparatus and method for use in providing dynamic bit rate encoding |
ES2239532B1 (es) * | 2004-02-06 | 2006-11-01 | Proyecto De Biomedicina Cima S.L. | Metodo para evaluar el riesgo y la predisposicion a desarrollar una patologia relacionada con la presencia de autoanticuerpos frente a epcr. |
US20070141625A1 (en) * | 2005-02-03 | 2007-06-21 | Santos Jose H | Method for assessing risk of and predisposition to development of a pathology related to the presence of anti-epcr autoantibodies |
US20070225749A1 (en) | 2006-02-03 | 2007-09-27 | Martin Brian B | Methods and devices for restoring blood flow within blocked vasculature |
EP2403583B1 (en) | 2009-03-06 | 2016-10-19 | Lazarus Effect, Inc. | Retrieval systems |
US10207240B2 (en) | 2009-11-03 | 2019-02-19 | Gen9, Inc. | Methods and microfluidic devices for the manipulation of droplets in high fidelity polynucleotide assembly |
US9260753B2 (en) | 2011-03-24 | 2016-02-16 | President And Fellows Of Harvard College | Single cell nucleic acid detection and analysis |
JP2017532024A (ja) | 2014-09-09 | 2017-11-02 | ザ・ブロード・インスティテュート・インコーポレイテッド | コンポジット単一細胞核酸分析のための液滴ベースの方法および機器 |
WO2016130647A1 (en) | 2015-02-11 | 2016-08-18 | Lazarus Effect, Inc. | Expandable tip medical devices and methods |
EP3268462B1 (en) | 2015-03-11 | 2021-08-11 | The Broad Institute, Inc. | Genotype and phenotype coupling |
US11092607B2 (en) | 2015-10-28 | 2021-08-17 | The Board Institute, Inc. | Multiplex analysis of single cell constituents |
WO2017075297A1 (en) | 2015-10-28 | 2017-05-04 | The Broad Institute Inc. | High-throughput dynamic reagent delivery system |
US12071663B2 (en) | 2016-01-15 | 2024-08-27 | Massachusetts Institute Of Technology | Semi-permeable arrays for analyzing biological systems and methods of using same |
US11072816B2 (en) | 2017-05-03 | 2021-07-27 | The Broad Institute, Inc. | Single-cell proteomic assay using aptamers |
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US4447236A (en) | 1982-02-05 | 1984-05-08 | Cordis Corporation | Infusion catheter system |
DE3330699A1 (de) * | 1983-08-25 | 1985-03-07 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur gleichzeitigen bestimmung von fibrinogen und fibrinogen-spaltprodukten im plasma |
US4610879A (en) | 1984-01-06 | 1986-09-09 | University Of Southern California | Fibrinolytic enzyme from snake vernom |
CA1237482A (en) | 1984-03-09 | 1988-05-31 | Frank B. Stiles | Catheter for effecting removal of obstructions from a biological duct |
US4755167A (en) | 1984-04-10 | 1988-07-05 | Research Corporation | In vivo method for distribution and stirring of therapeutic agents |
US4837148A (en) | 1984-10-30 | 1989-06-06 | Phillips Petroleum Company | Autonomous replication sequences for yeast strains of the genus pichia |
US4885242A (en) | 1984-10-30 | 1989-12-05 | Phillips Petroleum Company | Genes from pichia histidine pathway and uses thereof |
US4855231A (en) | 1984-10-30 | 1989-08-08 | Phillips Petroleum Company | Regulatory region for heterologous gene expression in yeast |
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EP0624642B1 (en) | 1993-05-12 | 1999-01-20 | Indian Council For Medical Research | Novel thrombolytic agent, process for preparing same and its use for the preparation of a thrombi dissolving medicament |
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US6261820B1 (en) | 1999-10-01 | 2001-07-17 | Amgen Inc. | Fibronolytically active polypeptide |
US6440414B1 (en) | 1999-10-01 | 2002-08-27 | Amgen Inc. | Pharmaceutical compositions of fibrinolytic agent |
US6455269B1 (en) | 1999-12-17 | 2002-09-24 | Amgen, Inc. | Method for localized administration of fibrinolytic metalloproteinases |
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-
1999
- 1999-10-01 US US09/411,329 patent/US6261820B1/en not_active Expired - Fee Related
-
2000
- 2000-09-20 YU YU59604A patent/YU59604A/sh unknown
- 2000-09-20 YU YU22502A patent/YU22502A/sh unknown
- 2000-09-29 RS YUP-2006/0033A patent/RS20060033A/sr unknown
- 2000-09-29 EP EP00965554A patent/EP1224298B1/en not_active Expired - Lifetime
- 2000-09-29 CA CA002386185A patent/CA2386185A1/en not_active Abandoned
- 2000-09-29 ES ES00965554T patent/ES2240167T3/es not_active Expired - Lifetime
- 2000-09-29 PL PL00355017A patent/PL355017A1/xx not_active IP Right Cessation
- 2000-09-29 IL IL14878700A patent/IL148787A0/xx unknown
- 2000-09-29 PT PT00965554T patent/PT1224298E/pt unknown
- 2000-09-29 DE DE60019147T patent/DE60019147T2/de not_active Expired - Fee Related
- 2000-09-29 KR KR1020067019636A patent/KR100700753B1/ko not_active IP Right Cessation
- 2000-09-29 EA EA200200410A patent/EA005944B1/ru not_active IP Right Cessation
- 2000-09-29 HU HU0202650A patent/HUP0202650A3/hu unknown
- 2000-09-29 AT AT00965554T patent/ATE292180T1/de not_active IP Right Cessation
- 2000-09-29 MX MXPA02003126A patent/MXPA02003126A/es active IP Right Grant
- 2000-09-29 SG SG200401889A patent/SG127720A1/en unknown
- 2000-09-29 AU AU76254/00A patent/AU767827B2/en not_active Ceased
- 2000-09-29 JP JP2001528597A patent/JP2003511034A/ja not_active Withdrawn
- 2000-09-29 EA EA200400290A patent/EA006487B1/ru unknown
- 2000-09-29 BR BR0014414-2A patent/BR0014414A/pt not_active Application Discontinuation
- 2000-09-29 CN CNB008163219A patent/CN100357430C/zh not_active Expired - Fee Related
- 2000-09-29 CN CNA2008100053253A patent/CN101230340A/zh active Pending
- 2000-09-29 SK SK423-2002A patent/SK4232002A3/sk not_active Application Discontinuation
- 2000-09-29 WO PCT/US2000/027029 patent/WO2001025445A1/en active IP Right Grant
- 2000-09-29 CZ CZ20021034A patent/CZ298502B6/cs not_active IP Right Cessation
- 2000-09-29 EP EP05006771A patent/EP1605049A3/en not_active Withdrawn
- 2000-09-29 KR KR1020027004225A patent/KR100711312B1/ko not_active IP Right Cessation
- 2000-09-29 DK DK00965554T patent/DK1224298T3/da active
- 2000-09-29 NZ NZ517951A patent/NZ517951A/en unknown
-
2001
- 2001-05-01 US US09/846,729 patent/US6617145B2/en not_active Expired - Fee Related
-
2002
- 2002-03-19 ZA ZA200202206A patent/ZA200202206B/en unknown
- 2002-03-26 NO NO20021501A patent/NO20021501L/no not_active Application Discontinuation
- 2002-04-04 BG BG106577A patent/BG106577A/bg unknown
-
2003
- 2003-01-24 HK HK03100667.9A patent/HK1049351B/zh not_active IP Right Cessation
- 2003-05-20 US US10/441,667 patent/US7195903B2/en not_active Expired - Fee Related
-
2007
- 2007-02-06 US US11/702,972 patent/US20080058256A1/en not_active Abandoned
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