SK372292A3 - Alpha-aryl-alpha-hydroxy-beta-imidazolinylpropionic acid amides, process for producing thereof, their use in medicaments and a pharmaceutical composition containing same - Google Patents

Alpha-aryl-alpha-hydroxy-beta-imidazolinylpropionic acid amides, process for producing thereof, their use in medicaments and a pharmaceutical composition containing same Download PDF

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Publication number
SK372292A3
SK372292A3 SK3722-92A SK372292A SK372292A3 SK 372292 A3 SK372292 A3 SK 372292A3 SK 372292 A SK372292 A SK 372292A SK 372292 A3 SK372292 A3 SK 372292A3
Authority
SK
Slovakia
Prior art keywords
group
carbon atoms
alkyl
fluorine
formula
Prior art date
Application number
SK3722-92A
Other languages
English (en)
Slovak (sk)
Other versions
SK278548B6 (en
Inventor
Wilfried Draber
Hilmar Bischoff
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SK372292A3 publication Critical patent/SK372292A3/sk
Publication of SK278548B6 publication Critical patent/SK278548B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/26—Radicals substituted by carbon atoms having three bonds to hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
SK3722-92A 1992-01-23 1992-12-17 Amides of alpha-aryl-aplpha-hydroxy-beta-imidazolinylpropionic acid, method of their producing, their use in medicaments and a pharmaceutical composition containing them SK278548B6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4201709A DE4201709A1 (de) 1992-01-23 1992-01-23 (alpha)-aryl-(alpha)-hydroxy-ss-imidazolinyl-propionsaeureamide

Publications (2)

Publication Number Publication Date
SK372292A3 true SK372292A3 (en) 1997-09-10
SK278548B6 SK278548B6 (en) 1997-09-10

Family

ID=6450062

Family Applications (1)

Application Number Title Priority Date Filing Date
SK3722-92A SK278548B6 (en) 1992-01-23 1992-12-17 Amides of alpha-aryl-aplpha-hydroxy-beta-imidazolinylpropionic acid, method of their producing, their use in medicaments and a pharmaceutical composition containing them

Country Status (22)

Country Link
US (1) US5334610A (fi)
EP (1) EP0552631B1 (fi)
JP (1) JPH05286942A (fi)
KR (1) KR930016401A (fi)
CN (1) CN1075714A (fi)
AT (1) ATE158576T1 (fi)
AU (1) AU650807B2 (fi)
CA (1) CA2087650A1 (fi)
CZ (1) CZ282024B6 (fi)
DE (2) DE4201709A1 (fi)
DK (1) DK0552631T3 (fi)
ES (1) ES2107562T3 (fi)
GR (1) GR3025179T3 (fi)
HU (1) HUT63394A (fi)
IL (1) IL104444A (fi)
MX (1) MX9300136A (fi)
MY (1) MY108826A (fi)
NZ (1) NZ245726A (fi)
PL (1) PL172005B1 (fi)
SK (1) SK278548B6 (fi)
TW (1) TW232011B (fi)
ZA (1) ZA93477B (fi)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403818B1 (en) 2000-02-28 2002-06-11 Eisai Co., Ltd. Process for producing α-hydroxy-carbonyl compound
EP1501790A4 (en) * 2002-04-18 2006-03-29 Univ Virginia NEW SODIUM CHANNEL BLOCKERS
WO2004050039A2 (en) * 2002-12-04 2004-06-17 Merck & Co., Inc. Spirocyclic ureas, compositions containing such compounds and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51143668A (en) * 1975-05-30 1976-12-10 Scherico Ltd Production of novel 22 imidazoline compound
DE2614240C3 (de) * 1976-04-02 1980-03-06 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von Acylcyaniden
JPS5936885B2 (ja) * 1976-06-24 1984-09-06 第一製薬株式会社 糖尿病治療剤
US4136188A (en) * 1976-06-25 1979-01-23 Daiichi Seiyaku Co., Ltd. Treatment of diabetes with 2-substituted-1,3-diazacyclic compounds
US4226876A (en) * 1976-12-20 1980-10-07 Burroughs Wellcome Co. Arthropodicidal imidazoline derivatives
DK344489D0 (da) * 1989-07-12 1989-07-12 Novo Nordisk As Substituerede 2-imidazoliner og fremstilling og anvendelse deraf

Also Published As

Publication number Publication date
ES2107562T3 (es) 1997-12-01
GR3025179T3 (en) 1998-02-27
CZ372292A3 (en) 1993-12-15
IL104444A (en) 1997-06-10
KR930016401A (ko) 1993-08-26
NZ245726A (en) 1996-01-26
ZA93477B (en) 1993-08-23
HUT63394A (en) 1993-08-30
MX9300136A (es) 1993-07-01
US5334610A (en) 1994-08-02
TW232011B (fi) 1994-10-11
PL297491A1 (en) 1993-08-09
CN1075714A (zh) 1993-09-01
PL172005B1 (pl) 1997-07-31
CA2087650A1 (en) 1993-07-24
SK278548B6 (en) 1997-09-10
DK0552631T3 (da) 1998-05-11
EP0552631A1 (de) 1993-07-28
JPH05286942A (ja) 1993-11-02
AU3188893A (en) 1993-07-29
DE59307401D1 (de) 1997-10-30
IL104444A0 (en) 1993-05-13
EP0552631B1 (de) 1997-09-24
HU9300181D0 (en) 1993-04-28
MY108826A (en) 1996-11-30
AU650807B2 (en) 1994-06-30
ATE158576T1 (de) 1997-10-15
CZ282024B6 (cs) 1997-04-16
DE4201709A1 (de) 1993-07-29

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