SK287621B6 - Spôsob produkcie heterológneho proteínu hubou - Google Patents

Spôsob produkcie heterológneho proteínu hubou Download PDF

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Publication number
SK287621B6
SK287621B6 SK740-2003A SK7402003A SK287621B6 SK 287621 B6 SK287621 B6 SK 287621B6 SK 7402003 A SK7402003 A SK 7402003A SK 287621 B6 SK287621 B6 SK 287621B6
Authority
SK
Slovakia
Prior art keywords
carbon source
ethanol
medium
phase
delivery
Prior art date
Application number
SK740-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK7402003A3 (en
Inventor
De Laar Antonius Martinus Johannes Van
Nigel Malcolm Lindner
Peter Nieuwpoort
Original Assignee
Unilever Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Nv filed Critical Unilever Nv
Publication of SK7402003A3 publication Critical patent/SK7402003A3/sk
Publication of SK287621B6 publication Critical patent/SK287621B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
SK740-2003A 2000-12-13 2001-11-16 Spôsob produkcie heterológneho proteínu hubou SK287621B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00311095 2000-12-13
PCT/EP2001/013457 WO2002048382A2 (en) 2000-12-13 2001-11-16 Method for the production of a heterologous protein by a fungus

Publications (2)

Publication Number Publication Date
SK7402003A3 SK7402003A3 (en) 2003-09-11
SK287621B6 true SK287621B6 (sk) 2011-04-05

Family

ID=8173440

Family Applications (1)

Application Number Title Priority Date Filing Date
SK740-2003A SK287621B6 (sk) 2000-12-13 2001-11-16 Spôsob produkcie heterológneho proteínu hubou

Country Status (18)

Country Link
US (1) US7560249B2 (xx)
EP (1) EP1349945B1 (xx)
JP (1) JP4494716B2 (xx)
CN (1) CN1481439A (xx)
AT (1) ATE351911T1 (xx)
AU (2) AU2002216049B2 (xx)
BR (1) BR0116675A (xx)
CA (1) CA2427665C (xx)
CZ (1) CZ303983B6 (xx)
DE (1) DE60126148T2 (xx)
ES (1) ES2278681T3 (xx)
HU (1) HU228689B1 (xx)
IL (1) IL156438A0 (xx)
MX (1) MXPA03005358A (xx)
PL (1) PL204737B1 (xx)
SK (1) SK287621B6 (xx)
WO (1) WO2002048382A2 (xx)
ZA (1) ZA200303353B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100093061A1 (en) * 2006-12-20 2010-04-15 Bodie Elizabeth A Assays for Improved Fungal Strains
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
AU2016273912B2 (en) * 2011-05-20 2018-08-02 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
PL2710114T3 (pl) * 2011-05-20 2022-01-17 H. Lundbeck A/S Wytwarzanie z wysoką czystością białek wielopodjednostkowych, takich jak przeciwciała, w transformowanych mikroorganizmach, takich jak pichia pastoris
US10150968B2 (en) 2011-08-19 2018-12-11 Alderbio Holdings Llc Multi-copy strategy for high-titer and high-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
US20140273094A1 (en) 2013-03-15 2014-09-18 Bristol-Myers Squibb Company Methods of enhancing protein quality and quantity by yeast fed-batch fermentation
WO2015042245A1 (en) * 2013-09-19 2015-03-26 The City University Of New York Process for increased yeast biomass
KR20170132154A (ko) 2015-03-31 2017-12-01 브이에이치스퀘어드 리미티드 프로테아제-절단가능 링커를 갖는 펩티드 구조물
EP3277706A1 (en) 2015-03-31 2018-02-07 VHsquared Limited Polypeptide comprising an immunoglobulin chain variable domain which binds to clostridium difficile toxin b
IL254577B2 (en) 2015-03-31 2023-11-01 Vhsquared Ltd polypeptides
WO2016156474A1 (en) 2015-03-31 2016-10-06 Vhsquared Limited Polypeptide comprising an immunoglobulin chain variable domain which binds to clostridium difficile toxin a
EP3519438A1 (en) 2016-09-30 2019-08-07 VHsquared Limited Compositions
JP2022538083A (ja) 2019-06-21 2022-08-31 ソリッソ ファーマシューティカルズ，インク． ポリペプチド
JP2022537780A (ja) 2019-06-21 2022-08-29 ソリッソ ファーマシューティカルズ，インク． ポリペプチド
WO2020254828A1 (en) 2019-06-21 2020-12-24 Vhsquared Limited Compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0481008B1 (en) 1989-07-07 1997-11-12 Unilever Plc Process for preparing a protein by a fungus transformed by multicopy integration of an expression vector
HUP9802321A3 (en) 1995-07-05 2000-10-30 Unilever Nv Expression of ocean fish antifreeze peptide in a food grade organism and its application in food products
DE60138333D1 (de) 2000-03-14 2009-05-28 Unilever Nv Variabele Domänen der schweren Kette eines Antikörpers gegen menschliche Ernährungslipasen und deren Verwendungen

Also Published As

Publication number Publication date
CZ20031659A3 (cs) 2003-11-12
BR0116675A (pt) 2003-11-04
CN1481439A (zh) 2004-03-10
HU228689B1 (hu) 2013-05-28
CA2427665C (en) 2011-10-11
EP1349945A2 (en) 2003-10-08
JP2004515249A (ja) 2004-05-27
PL362773A1 (en) 2004-11-02
CZ303983B6 (cs) 2013-07-31
SK7402003A3 (en) 2003-09-11
JP4494716B2 (ja) 2010-06-30
HUP0302655A2 (hu) 2003-11-28
AU1604902A (en) 2002-06-24
DE60126148D1 (de) 2007-03-08
WO2002048382A2 (en) 2002-06-20
IL156438A0 (en) 2004-01-04
ZA200303353B (en) 2004-04-30
ES2278681T3 (es) 2007-08-16
HUP0302655A3 (en) 2004-10-28
CA2427665A1 (en) 2002-06-20
WO2002048382A3 (en) 2003-01-30
EP1349945B1 (en) 2007-01-17
DE60126148T2 (de) 2007-05-31
AU2002216049B2 (en) 2005-11-24
MXPA03005358A (es) 2003-10-06
US7560249B2 (en) 2009-07-14
PL204737B1 (pl) 2010-02-26
US20040077069A1 (en) 2004-04-22
ATE351911T1 (de) 2007-02-15

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Legal Events

Date Code Title Description
PC4A Assignment and transfer of rights

Owner name: UNILEVER IP HOLDINGS B.V., AL ROTTERDAM, NL

Free format text: FORMER OWNER: UNILEVER NV, AL ROTTERDAM, NL

Effective date: 20210602

MK4A Patent expired

Expiry date: 20211116