SK286719B6 - Použitie derivátov kyseliny fumarovej na liečenie mitochondriálnych chorôb - Google Patents

Použitie derivátov kyseliny fumarovej na liečenie mitochondriálnych chorôb Download PDF

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Publication number
SK286719B6
SK286719B6 SK652-2002A SK6522002A SK286719B6 SK 286719 B6 SK286719 B6 SK 286719B6 SK 6522002 A SK6522002 A SK 6522002A SK 286719 B6 SK286719 B6 SK 286719B6
Authority
SK
Slovakia
Prior art keywords
fumarate
fumaric acid
methyl
ethyl
use according
Prior art date
Application number
SK652-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK6522002A3 (en
Inventor
Rajendra Kumar Joshi
Hans-Peter Strebel
Original Assignee
Fumapharm Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fumapharm Ag filed Critical Fumapharm Ag
Publication of SK6522002A3 publication Critical patent/SK6522002A3/sk
Publication of SK286719B6 publication Critical patent/SK286719B6/sk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
SK652-2002A 2000-01-10 2000-12-11 Použitie derivátov kyseliny fumarovej na liečenie mitochondriálnych chorôb SK286719B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10000577A DE10000577A1 (de) 2000-01-10 2000-01-10 Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten
PCT/EP2000/012504 WO2001051047A1 (de) 2000-01-10 2000-12-11 Verwendung von fumarsäurederivaten zur behandlung mitochondrialer krankheiten

Publications (2)

Publication Number Publication Date
SK6522002A3 SK6522002A3 (en) 2002-11-06
SK286719B6 true SK286719B6 (sk) 2009-04-06

Family

ID=7627026

Family Applications (1)

Application Number Title Priority Date Filing Date
SK652-2002A SK286719B6 (sk) 2000-01-10 2000-12-11 Použitie derivátov kyseliny fumarovej na liečenie mitochondriálnych chorôb

Country Status (28)

Country Link
US (1) US6858750B2 (hu)
EP (1) EP1248606B1 (hu)
JP (1) JP2003529556A (hu)
CN (1) CN1433303A (hu)
AT (1) ATE329590T1 (hu)
AU (1) AU772409B2 (hu)
BG (1) BG65468B1 (hu)
BR (1) BR0016935A (hu)
CA (1) CA2390886C (hu)
CY (1) CY1105462T1 (hu)
CZ (1) CZ303680B6 (hu)
DE (2) DE10000577A1 (hu)
DK (1) DK1248606T3 (hu)
EE (1) EE05051B1 (hu)
ES (1) ES2265367T3 (hu)
HU (1) HU229138B1 (hu)
IL (2) IL150516A0 (hu)
MX (1) MXPA02006695A (hu)
NO (1) NO326875B1 (hu)
NZ (1) NZ518781A (hu)
PL (1) PL223342B1 (hu)
PT (1) PT1248606E (hu)
RS (1) RS50185B (hu)
RU (1) RU2218918C1 (hu)
SI (1) SI1248606T1 (hu)
SK (1) SK286719B6 (hu)
WO (1) WO2001051047A1 (hu)
ZA (1) ZA200205481B (hu)

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DK2564839T3 (en) * 2009-01-09 2016-07-25 Forward Pharma As A pharmaceutical formulation comprising one or more fumaric acid esters in an erosion matrix
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SG11201404705YA (en) 2012-02-07 2014-10-30 Biogen Idec Inc Pharmaceutical compositions containing dimethyl fumarate
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ES2733961T3 (es) 2012-12-21 2019-12-03 Biogen Ma Inc Derivados de fumarato sustituidos con deuterio
US8669281B1 (en) 2013-03-14 2014-03-11 Alkermes Pharma Ireland Limited Prodrugs of fumarates and their use in treating various diseases
DK2970101T3 (en) 2013-03-14 2018-08-20 Alkermes Pharma Ireland Ltd PRO-DRUGS OF FUMARATES AND THEIR USE IN TREATING DIFFERENT DISEASES
WO2014160633A1 (en) 2013-03-24 2014-10-02 Xenoport, Inc. Pharmaceutical compositions of dimethyl fumarate
WO2014197860A1 (en) 2013-06-07 2014-12-11 Xenoport, Inc. Method of making monomethyl fumarate
US9421182B2 (en) 2013-06-21 2016-08-23 Xenoport, Inc. Cocrystals of dimethyl fumarate
TW201516020A (zh) 2013-09-06 2015-05-01 Xenoport Inc （ｎ，ｎ－二乙基胺甲醯基）甲基（２ｅ）丁－２－烯－１，４－二酸甲酯之晶形、合成方法及用途
CA2940845C (en) 2014-02-24 2019-09-24 Alkermes Pharma Ireland Limited Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases
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Also Published As

Publication number Publication date
CY1105462T1 (el) 2010-04-28
EP1248606A1 (de) 2002-10-16
YU51402A (sh) 2006-01-16
CA2390886A1 (en) 2001-07-19
SK6522002A3 (en) 2002-11-06
MXPA02006695A (es) 2002-10-23
CZ20021522A3 (cs) 2002-10-16
WO2001051047A1 (de) 2001-07-19
CZ303680B6 (cs) 2013-02-27
ES2265367T3 (es) 2007-02-16
WO2001051047A8 (de) 2001-08-16
NO20022175D0 (no) 2002-05-07
NO20022175L (no) 2002-05-07
NZ518781A (en) 2004-04-30
AU3156601A (en) 2001-07-24
NO326875B1 (no) 2009-03-09
PL356714A1 (en) 2004-06-28
HUP0204182A3 (en) 2003-05-28
HU229138B1 (en) 2013-08-28
ATE329590T1 (de) 2006-07-15
RU2218918C1 (ru) 2003-12-20
US6858750B2 (en) 2005-02-22
DE10000577A1 (de) 2001-07-26
AU772409B2 (en) 2004-04-29
HUP0204182A2 (hu) 2003-04-28
DK1248606T3 (da) 2006-08-21
CA2390886C (en) 2008-08-19
PT1248606E (pt) 2006-08-31
RS50185B (sr) 2009-05-06
EP1248606B1 (de) 2006-06-14
BG106685A (en) 2003-01-31
ZA200205481B (en) 2004-01-28
EE05051B1 (et) 2008-08-15
EE200200333A (et) 2003-08-15
DE50013000D1 (de) 2006-07-27
IL150516A (en) 2009-02-11
SI1248606T1 (sl) 2006-10-31
PL223342B1 (pl) 2016-10-31
IL150516A0 (en) 2003-02-12
CN1433303A (zh) 2003-07-30
JP2003529556A (ja) 2003-10-07
BG65468B1 (bg) 2008-09-30
US20030013761A1 (en) 2003-01-16
BR0016935A (pt) 2003-04-01

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Legal Events

Date Code Title Description
TC4A Change of owner's name

Owner name: BIOGEN IDEC INTERNATIONAL GMBH, ZUG, CH

Effective date: 20140623

TC4A Change of owner's name

Owner name: BIOGEN INTERNATIONAL GMBH, ZUG, CH

Effective date: 20170622

MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20161211