YU51402A - Primena derivata fumarne kiseline u lečenju mitohondrijalnih bolesti - Google Patents

Primena derivata fumarne kiseline u lečenju mitohondrijalnih bolesti

Info

Publication number
YU51402A
YU51402A YU51402A YUP51402A YU51402A YU 51402 A YU51402 A YU 51402A YU 51402 A YU51402 A YU 51402A YU P51402 A YUP51402 A YU P51402A YU 51402 A YU51402 A YU 51402A
Authority
YU
Yugoslavia
Prior art keywords
fumaric acid
acid derivatives
mitochondrial diseases
treating mitochondrial
disease
Prior art date
Application number
YU51402A
Other languages
English (en)
Inventor
Rajendra Kumar Joshi
Hans-Peter Strebel
Original Assignee
Fumapharm Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fumapharm Ag. filed Critical Fumapharm Ag.
Publication of YU51402A publication Critical patent/YU51402A/sh
Publication of RS50185B publication Critical patent/RS50185B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Pronalazak se odnosi na primenu pojedinih derivata fumarne kiseline ili njihovih smeša za proizvodnju farmaceutskog preparata za lečenje mitohondrijalnih oboljenja, naročito za lečenje Parkinsonovog sindroma, Alchajmerove bolesti, Chorea-Huntington-bolesti, pigmentozne retinopatije i mitohondrijalne encefalomiopatije. Prvenstveno se radi kod tog ili tih derivata fumarne kiseline o takvim, izabranim iz grupe, sastavljene iz dialkilestara fumarne kiseline i monoalkilestara fumarne kiseline u obliku slobodne kiseline ili jedne soli od toga.[The invention relates to the use of single fumaric acid derivatives, or mixtures thereof for producing a pharmaceutical preparation used to treat mitochondrial diseases, in particular to treat Parkinson's disease, Alzheimer's disease, Huntington's chorea, pigmental retinopathy and mitochondrial encephalomyopathy. The fumaric acid derivative or derivatives are selected from the group consisting of fumaric acid dialkyl esters and fumaric acid monoalkyl esters and take the form of free acids or a salt thereof.
YUP-514/02A 2000-01-10 2000-12-11 Primena derivata fumarne kiseline u lečenju mitohondrijalnih bolesti RS50185B (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10000577A DE10000577A1 (de) 2000-01-10 2000-01-10 Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten

Publications (2)

Publication Number Publication Date
YU51402A true YU51402A (sh) 2006-01-16
RS50185B RS50185B (sr) 2009-05-06

Family

ID=7627026

Country Status (28)

Country Link
US (1) US6858750B2 (sh)
EP (1) EP1248606B1 (sh)
JP (1) JP2003529556A (sh)
CN (1) CN1433303A (sh)
AT (1) ATE329590T1 (sh)
AU (1) AU772409B2 (sh)
BG (1) BG65468B1 (sh)
BR (1) BR0016935A (sh)
CA (1) CA2390886C (sh)
CY (1) CY1105462T1 (sh)
CZ (1) CZ303680B6 (sh)
DE (2) DE10000577A1 (sh)
DK (1) DK1248606T3 (sh)
EE (1) EE05051B1 (sh)
ES (1) ES2265367T3 (sh)
HU (1) HU229138B1 (sh)
IL (2) IL150516A0 (sh)
MX (1) MXPA02006695A (sh)
NO (1) NO326875B1 (sh)
NZ (1) NZ518781A (sh)
PL (1) PL223342B1 (sh)
PT (1) PT1248606E (sh)
RS (1) RS50185B (sh)
RU (1) RU2218918C1 (sh)
SI (1) SI1248606T1 (sh)
SK (1) SK286719B6 (sh)
WO (1) WO2001051047A1 (sh)
ZA (1) ZA200205481B (sh)

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WO2010079221A1 (en) * 2009-01-09 2010-07-15 Forward Pharma A/S Pharmaceutical composition comprising one or more fumaric acid esters
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HUE040044T2 (hu) 2013-03-14 2019-02-28 Alkermes Pharma Ireland Ltd Fumarátok prodrugjai, és azok alkalmazása különbözõ betegségek kezelésében
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US9604922B2 (en) 2014-02-24 2017-03-28 Alkermes Pharma Ireland Limited Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases
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Also Published As

Publication number Publication date
DE50013000D1 (de) 2006-07-27
CZ20021522A3 (cs) 2002-10-16
CZ303680B6 (cs) 2013-02-27
MXPA02006695A (es) 2002-10-23
CA2390886A1 (en) 2001-07-19
SI1248606T1 (sl) 2006-10-31
EP1248606A1 (de) 2002-10-16
ES2265367T3 (es) 2007-02-16
HUP0204182A3 (en) 2003-05-28
BG65468B1 (bg) 2008-09-30
IL150516A0 (en) 2003-02-12
US6858750B2 (en) 2005-02-22
ATE329590T1 (de) 2006-07-15
CY1105462T1 (el) 2010-04-28
WO2001051047A1 (de) 2001-07-19
HU229138B1 (en) 2013-08-28
CN1433303A (zh) 2003-07-30
PT1248606E (pt) 2006-08-31
HUP0204182A2 (hu) 2003-04-28
EE05051B1 (et) 2008-08-15
EP1248606B1 (de) 2006-06-14
SK286719B6 (sk) 2009-04-06
AU772409B2 (en) 2004-04-29
JP2003529556A (ja) 2003-10-07
PL356714A1 (en) 2004-06-28
NO20022175D0 (no) 2002-05-07
PL223342B1 (pl) 2016-10-31
SK6522002A3 (en) 2002-11-06
BR0016935A (pt) 2003-04-01
RS50185B (sr) 2009-05-06
NO326875B1 (no) 2009-03-09
BG106685A (en) 2003-01-31
WO2001051047A8 (de) 2001-08-16
ZA200205481B (en) 2004-01-28
EE200200333A (et) 2003-08-15
DK1248606T3 (da) 2006-08-21
NO20022175L (no) 2002-05-07
US20030013761A1 (en) 2003-01-16
IL150516A (en) 2009-02-11
RU2218918C1 (ru) 2003-12-20
DE10000577A1 (de) 2001-07-26
AU3156601A (en) 2001-07-24
CA2390886C (en) 2008-08-19
NZ518781A (en) 2004-04-30

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