SK286610B6 - Spôsob prípravy derivátov distamycínu - Google Patents

Spôsob prípravy derivátov distamycínu Download PDF

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Publication number
SK286610B6
SK286610B6 SK832-2003A SK8322003A SK286610B6 SK 286610 B6 SK286610 B6 SK 286610B6 SK 8322003 A SK8322003 A SK 8322003A SK 286610 B6 SK286610 B6 SK 286610B6
Authority
SK
Slovakia
Prior art keywords
formula
compound
process according
carried out
pharmaceutically acceptable
Prior art date
Application number
SK832-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK8322003A3 (en
Inventor
Francesco Caldarelli
Lucio Ceriani
Ilaria Candiani
Original Assignee
Nerviano Medical Sciences S. R. L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nerviano Medical Sciences S. R. L. filed Critical Nerviano Medical Sciences S. R. L.
Publication of SK8322003A3 publication Critical patent/SK8322003A3/sk
Publication of SK286610B6 publication Critical patent/SK286610B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/42—Nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SK832-2003A 2000-11-28 2001-11-07 Spôsob prípravy derivátov distamycínu SK286610B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0029004.9A GB0029004D0 (en) 2000-11-28 2000-11-28 Process for preparing distamycin derivatives
PCT/EP2001/013050 WO2002044147A1 (en) 2000-11-28 2001-11-07 Process for preparing distamycin derivatives

Publications (2)

Publication Number Publication Date
SK8322003A3 SK8322003A3 (en) 2003-10-07
SK286610B6 true SK286610B6 (sk) 2009-02-05

Family

ID=9904031

Family Applications (1)

Application Number Title Priority Date Filing Date
SK832-2003A SK286610B6 (sk) 2000-11-28 2001-11-07 Spôsob prípravy derivátov distamycínu

Country Status (31)

Country Link
US (1) US6906199B2 (et)
EP (1) EP1347958B1 (et)
JP (1) JP4574944B2 (et)
KR (1) KR100847234B1 (et)
CN (1) CN1190418C (et)
AR (1) AR035073A1 (et)
AT (1) ATE287395T1 (et)
AU (2) AU2002220696B2 (et)
BR (1) BR0115351A (et)
CA (1) CA2427177C (et)
CZ (1) CZ303461B6 (et)
DE (1) DE60108528T2 (et)
EA (1) EA005399B1 (et)
EE (1) EE05218B1 (et)
ES (1) ES2236365T3 (et)
GB (1) GB0029004D0 (et)
HK (1) HK1060732A1 (et)
HU (1) HU229670B1 (et)
IL (2) IL155385A0 (et)
MX (1) MXPA03004679A (et)
MY (1) MY134563A (et)
NO (1) NO324601B1 (et)
NZ (1) NZ525230A (et)
PE (1) PE20020551A1 (et)
PL (1) PL205821B1 (et)
PT (1) PT1347958E (et)
SI (1) SI1347958T1 (et)
SK (1) SK286610B6 (et)
TW (1) TWI287002B (et)
WO (1) WO2002044147A1 (et)
ZA (1) ZA200302771B (et)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100842363B1 (ko) * 2007-04-05 2008-07-02 김춘동 튜브 짜개
EP2970586B1 (en) * 2013-03-15 2022-12-07 Genzyme Corporation Amine functional polyamides
JP2015080906A (ja) * 2013-10-23 2015-04-27 セイコーエプソン株式会社 液体収容容器、液体噴射装置
JPWO2023149487A1 (et) * 2022-02-02 2023-08-10

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8612218D0 (en) 1986-05-20 1986-06-25 Erba Farmitalia Site specific alkylating agents
EP0265719B1 (en) 1986-10-07 1991-03-06 Boehringer Mannheim Italia S.P.A. Pharmaceutical compositions having antineoplastic activity
GB8906709D0 (en) 1989-03-23 1989-05-10 Creighton Andrew M Acryloyl substituted pyrrole derivatives
JP2919867B2 (ja) 1989-09-27 1999-07-19 千寿製薬株式会社 抗腫瘍剤
IT1272234B (it) * 1994-05-02 1997-06-16 Consiglio Nazionale Ricerche Derivati glutationici delle antracicline e procedimento per ottenerli.
GB9416005D0 (en) 1994-08-08 1994-09-28 Erba Carlo Spa Peptidic compounds analogous to distamycin a and process for their preparation
US5880097A (en) * 1996-01-04 1999-03-09 Terrapin Techologies, Inc. Tethered prodrugs
GB9610079D0 (en) 1996-05-14 1996-07-17 Pharmacia Spa Distamycin deriratives process for preparing them and their use as antitumor and antiviral agents
KR100469778B1 (ko) * 1996-05-14 2005-05-16 파머시아 앤 업잔 에스.피.에이. 디스타마이신유도체,이의제조방법,및항종양성및항바이러스성제제로서의이들의용도
GB9615692D0 (en) * 1996-07-25 1996-09-04 Pharmacia Spa Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB9623522D0 (en) 1996-11-11 1997-01-08 Pharmacia & Upjohn Spa Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents
GB9727524D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Synergistic antitumor composition containing a biologically active ureido compound
GB9806689D0 (en) 1998-03-27 1998-05-27 Pharmacia & Upjohn Spa Acryloyl derivatives analogous to distamycin,process for preparing them,and their use as antitumour and antiviral agents
GB9806692D0 (en) 1998-03-27 1998-05-27 Pharmacia & Upjohn Spa Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents
GB9816652D0 (en) 1998-07-30 1998-09-30 Pharmacia & Upjohn Spa Sulfurated distamycin derivatives process for preparing them and their use as antitumor agents
GB9816653D0 (en) 1998-07-30 1998-09-30 Pharmacia & Upjohn Spa Oxidised sulfurated distamycin derivatives process for preparing them and their use as antitumor agents

Also Published As

Publication number Publication date
KR20030066681A (ko) 2003-08-09
PE20020551A1 (es) 2002-06-12
EE200300204A (et) 2003-08-15
ZA200302771B (en) 2004-04-13
IL155385A0 (en) 2003-11-23
CA2427177C (en) 2010-01-19
IL155385A (en) 2009-02-11
JP4574944B2 (ja) 2010-11-04
PL362179A1 (en) 2004-10-18
EA200300617A1 (ru) 2003-10-30
AU2069602A (en) 2002-06-11
HU229670B1 (en) 2014-04-28
EA005399B1 (ru) 2005-02-24
EP1347958A1 (en) 2003-10-01
HK1060732A1 (en) 2004-08-20
NO324601B1 (no) 2007-11-26
SI1347958T1 (et) 2005-08-31
NO20032297D0 (no) 2003-05-21
CN1476431A (zh) 2004-02-18
US20040077550A1 (en) 2004-04-22
DE60108528T2 (de) 2006-03-23
PT1347958E (pt) 2005-05-31
WO2002044147A1 (en) 2002-06-06
CN1190418C (zh) 2005-02-23
CA2427177A1 (en) 2002-06-06
GB0029004D0 (en) 2001-01-10
TWI287002B (en) 2007-09-21
ATE287395T1 (de) 2005-02-15
US6906199B2 (en) 2005-06-14
BR0115351A (pt) 2003-08-26
CZ20031132A3 (cs) 2003-08-13
DE60108528D1 (de) 2005-02-24
AR035073A1 (es) 2004-04-14
EE05218B1 (et) 2009-10-15
HUP0302158A2 (hu) 2003-09-29
SK8322003A3 (en) 2003-10-07
ES2236365T3 (es) 2005-07-16
KR100847234B1 (ko) 2008-07-18
NZ525230A (en) 2004-06-25
MY134563A (en) 2007-12-31
EP1347958B1 (en) 2005-01-19
JP2004517830A (ja) 2004-06-17
AU2002220696B2 (en) 2006-11-30
NO20032297L (no) 2003-05-21
MXPA03004679A (es) 2003-09-05
PL205821B1 (pl) 2010-05-31
CZ303461B6 (cs) 2012-09-26

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20121107