SK285561B6 - Semihydrochlorid kyseliny 8-kyano-1-cyklopropyl-7-(1S,6S-2,8- diazabicyklo-[4.3.0]nonan-8-yl)-6-fluór-1,4-dihydro-4-oxo-3- chinolínkarboxylovej, spôsob prípravy a jeho použitie v zmesiach s antibakteriálnymi účinkami - Google Patents

Semihydrochlorid kyseliny 8-kyano-1-cyklopropyl-7-(1S,6S-2,8- diazabicyklo-[4.3.0]nonan-8-yl)-6-fluór-1,4-dihydro-4-oxo-3- chinolínkarboxylovej, spôsob prípravy a jeho použitie v zmesiach s antibakteriálnymi účinkami Download PDF

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Publication number
SK285561B6
SK285561B6 SK684-2001A SK6842001A SK285561B6 SK 285561 B6 SK285561 B6 SK 285561B6 SK 6842001 A SK6842001 A SK 6842001A SK 285561 B6 SK285561 B6 SK 285561B6
Authority
SK
Slovakia
Prior art keywords
cyclopropyl
fluoro
oxo
dihydro
diazabicyclo
Prior art date
Application number
SK684-2001A
Other languages
English (en)
Slovak (sk)
Other versions
SK6842001A3 (en
Inventor
Thomas Himmler
Hubert Rast
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of SK6842001A3 publication Critical patent/SK6842001A3/sk
Publication of SK285561B6 publication Critical patent/SK285561B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK684-2001A 1998-11-25 1999-11-15 Semihydrochlorid kyseliny 8-kyano-1-cyklopropyl-7-(1S,6S-2,8- diazabicyklo-[4.3.0]nonan-8-yl)-6-fluór-1,4-dihydro-4-oxo-3- chinolínkarboxylovej, spôsob prípravy a jeho použitie v zmesiach s antibakteriálnymi účinkami SK285561B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19854357A DE19854357A1 (de) 1998-11-25 1998-11-25 Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
PCT/EP1999/008778 WO2000031077A1 (de) 1998-11-25 1999-11-15 Semi-hydrochlorid von 8-cyan-1- cyclopropyl -7-(1s,6s-2, 8-diazabicyclo [4.3.0]nonan -8-yl)-6- fluor-1, 4-dihydro-4- oxo-3- chinolincarbonsäure

Publications (2)

Publication Number Publication Date
SK6842001A3 SK6842001A3 (en) 2001-12-03
SK285561B6 true SK285561B6 (sk) 2007-03-01

Family

ID=7888961

Family Applications (1)

Application Number Title Priority Date Filing Date
SK684-2001A SK285561B6 (sk) 1998-11-25 1999-11-15 Semihydrochlorid kyseliny 8-kyano-1-cyklopropyl-7-(1S,6S-2,8- diazabicyklo-[4.3.0]nonan-8-yl)-6-fluór-1,4-dihydro-4-oxo-3- chinolínkarboxylovej, spôsob prípravy a jeho použitie v zmesiach s antibakteriálnymi účinkami

Country Status (28)

Country Link
US (1) US6995170B1 (xx)
EP (1) EP1133495B1 (xx)
JP (1) JP2002530408A (xx)
KR (1) KR100740956B1 (xx)
CN (1) CN1176921C (xx)
AR (1) AR023709A1 (xx)
AT (1) ATE225790T1 (xx)
AU (1) AU759769B2 (xx)
BR (1) BR9915684A (xx)
CA (1) CA2351714C (xx)
CZ (1) CZ300058B6 (xx)
DE (2) DE19854357A1 (xx)
DK (1) DK1133495T3 (xx)
ES (1) ES2181488T3 (xx)
HK (1) HK1042704B (xx)
HU (1) HUP0104367A3 (xx)
IL (2) IL142837A0 (xx)
NO (1) NO318053B1 (xx)
NZ (1) NZ511863A (xx)
PL (1) PL196508B1 (xx)
PT (1) PT1133495E (xx)
RU (1) RU2242475C2 (xx)
SK (1) SK285561B6 (xx)
TR (1) TR200101443T2 (xx)
TW (1) TWI234565B (xx)
UA (1) UA67875C2 (xx)
WO (1) WO2000031077A1 (xx)
ZA (1) ZA013317B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE10224086A1 (de) * 2002-05-31 2003-12-11 Bayer Ag Pharmazeutische Zubereitungen zur oralen Anwendung enthaltend wirkstoffbeladene Ionentauscherharze sowie strukturviskose Gelbildner als Verdicker
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102006049520A1 (de) * 2006-10-20 2008-04-24 Bayer Healthcare Ag Verfahren zur Herstellung von Pradofloxacin
JP7257322B2 (ja) 2017-02-13 2023-04-13 バイエル・アニマル・ヘルス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング プラドフロキサシンを含有する液体組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
JP4338217B2 (ja) * 1996-02-23 2009-10-07 バイエル・アニマル・ヘルス・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 置換可能な８―シアノ―１―シクロプロピル―７―（２，８―ジアザビシクロ―［４．３．０］―ノナン―８―イル）―６―フルオロ―１，４―ジヒドロ―４―オキソ―３―キノリンカルボン酸およびそれらの誘導体
DE19633805A1 (de) * 1996-02-23 1997-08-28 Bayer Ag Gegenenenfalls substituierte 8-Cyan-l-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre Derivate
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure

Also Published As

Publication number Publication date
PT1133495E (pt) 2003-02-28
EP1133495A1 (de) 2001-09-19
TWI234565B (en) 2005-06-21
NZ511863A (en) 2003-05-30
PL196508B1 (pl) 2008-01-31
UA67875C2 (uk) 2004-07-15
CZ20011753A3 (cs) 2001-09-12
IL142837A0 (en) 2002-03-10
NO20012532L (no) 2001-07-02
RU2242475C2 (ru) 2004-12-20
JP2002530408A (ja) 2002-09-17
AU1271600A (en) 2000-06-13
HUP0104367A3 (en) 2002-12-28
ATE225790T1 (de) 2002-10-15
CA2351714C (en) 2010-06-15
BR9915684A (pt) 2001-08-14
WO2000031077A1 (de) 2000-06-02
CN1328557A (zh) 2001-12-26
AR023709A1 (es) 2002-09-04
IL142837A (en) 2006-08-01
ES2181488T3 (es) 2003-02-16
SK6842001A3 (en) 2001-12-03
ZA013317B (en) 2002-06-26
DK1133495T3 (da) 2003-02-10
HK1042704B (zh) 2005-09-09
NO20012532D0 (no) 2001-05-23
DE19854357A1 (de) 2000-05-31
NO318053B1 (no) 2005-01-24
CN1176921C (zh) 2004-11-24
HK1042704A1 (en) 2002-08-23
PL347799A1 (en) 2002-04-22
KR100740956B1 (ko) 2007-07-19
CZ300058B6 (cs) 2009-01-21
US6995170B1 (en) 2006-02-07
EP1133495B1 (de) 2002-10-09
DE59903063D1 (de) 2002-11-14
HUP0104367A2 (hu) 2002-02-28
AU759769B2 (en) 2003-05-01
KR20010075694A (ko) 2001-08-09
TR200101443T2 (tr) 2001-09-21
CA2351714A1 (en) 2000-06-02

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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20101115