SK285540B6 - Kryštalická modifikácia A kyseliny 8-kyano-1-cyklopropyl-7-(1S, 6S-2,8-diazabicyklo-[4.3.0]nonan-8-yl)-6-fluór-1,4-dihydro-4-oxo- 3-chinolínkarboxylovej, spôsob prípravy a jej použitie vo farmaceutických prípravkoch - Google Patents

Kryštalická modifikácia A kyseliny 8-kyano-1-cyklopropyl-7-(1S, 6S-2,8-diazabicyklo-[4.3.0]nonan-8-yl)-6-fluór-1,4-dihydro-4-oxo- 3-chinolínkarboxylovej, spôsob prípravy a jej použitie vo farmaceutických prípravkoch Download PDF

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Publication number
SK285540B6
SK285540B6 SK682-2001A SK6822001A SK285540B6 SK 285540 B6 SK285540 B6 SK 285540B6 SK 6822001 A SK6822001 A SK 6822001A SK 285540 B6 SK285540 B6 SK 285540B6
Authority
SK
Slovakia
Prior art keywords
diazabicyclo
cyclopropyl
oxo
dihydro
fluoro
Prior art date
Application number
SK682-2001A
Other languages
English (en)
Slovak (sk)
Other versions
SK6822001A3 (en
Inventor
Thomas Himmler
Werner Hallenbach
Hubert Rast
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of SK6822001A3 publication Critical patent/SK6822001A3/sk
Publication of SK285540B6 publication Critical patent/SK285540B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
SK682-2001A 1998-11-25 1999-11-15 Kryštalická modifikácia A kyseliny 8-kyano-1-cyklopropyl-7-(1S, 6S-2,8-diazabicyklo-[4.3.0]nonan-8-yl)-6-fluór-1,4-dihydro-4-oxo- 3-chinolínkarboxylovej, spôsob prípravy a jej použitie vo farmaceutických prípravkoch SK285540B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19854356A DE19854356A1 (de) 1998-11-25 1998-11-25 Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
PCT/EP1999/008775 WO2000031075A1 (de) 1998-11-25 1999-11-15 Kristallmodifikation a von 8-cyan-1- cyclopropyl-7- (1s,6s-2,8 -diazabicyclo -[4.3.0]nonan -8-yl)-6- fluor-1,4- dihydro-4- oxo-3- chinolincarbonsäure

Publications (2)

Publication Number Publication Date
SK6822001A3 SK6822001A3 (en) 2001-12-03
SK285540B6 true SK285540B6 (sk) 2007-03-01

Family

ID=7888960

Family Applications (1)

Application Number Title Priority Date Filing Date
SK682-2001A SK285540B6 (sk) 1998-11-25 1999-11-15 Kryštalická modifikácia A kyseliny 8-kyano-1-cyklopropyl-7-(1S, 6S-2,8-diazabicyklo-[4.3.0]nonan-8-yl)-6-fluór-1,4-dihydro-4-oxo- 3-chinolínkarboxylovej, spôsob prípravy a jej použitie vo farmaceutických prípravkoch

Country Status (27)

Country Link
US (1) US6436955B1 (ko)
EP (1) EP1133496B1 (ko)
JP (1) JP2002530406A (ko)
KR (1) KR100740947B1 (ko)
CN (1) CN1135230C (ko)
AR (1) AR031216A1 (ko)
AT (1) ATE264858T1 (ko)
AU (1) AU763883B2 (ko)
BR (1) BRPI9915669B8 (ko)
CA (1) CA2351712C (ko)
CZ (1) CZ300016B6 (ko)
DE (2) DE19854356A1 (ko)
DK (1) DK1133496T3 (ko)
ES (1) ES2217843T3 (ko)
HK (1) HK1042703B (ko)
HU (1) HUP0104465A3 (ko)
IL (2) IL142696A0 (ko)
NO (1) NO318066B1 (ko)
NZ (1) NZ511861A (ko)
PL (1) PL196085B1 (ko)
PT (1) PT1133496E (ko)
RU (1) RU2247122C2 (ko)
SK (1) SK285540B6 (ko)
TR (1) TR200101438T2 (ko)
TW (1) TW576835B (ko)
UA (1) UA67874C2 (ko)
WO (1) WO2000031075A1 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE102004015981A1 (de) 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
MX2019009572A (es) 2017-02-13 2019-10-02 Bayer Animal Health Gmbh Composicion liquida que contiene pradofloxacina.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2676521B2 (ja) * 1988-03-22 1997-11-17 北陸製薬株式会社 キノロンカルボン酸化合物ｉ型結晶の製造法
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
CZ138297A3 (en) 1994-11-18 1997-10-15 Pharmacia & Upjohn Novel physically stable form of solid fluoroquinolone
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
DK0882049T3 (da) * 1996-02-23 2003-03-03 Bayer Ag Eventuelt substituerede 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-quinolincarboxylsyrer og deres derivater
DE19633805A1 (de) * 1996-02-23 1997-08-28 Bayer Ag Gegenenenfalls substituierte 8-Cyan-l-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre Derivate
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure

Also Published As

Publication number Publication date
HK1042703B (zh) 2004-12-03
IL142696A0 (en) 2002-03-10
KR100740947B1 (ko) 2007-07-19
DK1133496T3 (da) 2004-08-09
NZ511861A (en) 2002-12-20
ES2217843T3 (es) 2004-11-01
CZ300016B6 (cs) 2009-01-14
NO20012460L (no) 2001-05-18
HK1042703A1 (en) 2002-08-23
ATE264858T1 (de) 2004-05-15
BRPI9915669B8 (pt) 2021-07-06
NO318066B1 (no) 2005-01-31
CN1328558A (zh) 2001-12-26
US6436955B1 (en) 2002-08-20
BRPI9915669A (pt) 2001-08-14
CA2351712A1 (en) 2000-06-02
KR20010080926A (ko) 2001-08-25
AR031216A1 (es) 2003-09-17
PL196085B1 (pl) 2007-12-31
NO20012460D0 (no) 2001-05-18
EP1133496A1 (de) 2001-09-19
CN1135230C (zh) 2004-01-21
CA2351712C (en) 2011-07-12
TW576835B (en) 2004-02-21
HUP0104465A2 (hu) 2002-04-29
PL347786A1 (en) 2002-04-22
EP1133496B1 (de) 2004-04-21
AU763883B2 (en) 2003-07-31
DE19854356A1 (de) 2000-05-31
AU1553300A (en) 2000-06-13
BRPI9915669B1 (pt) 2017-07-04
JP2002530406A (ja) 2002-09-17
IL142696A (en) 2006-04-10
WO2000031075A1 (de) 2000-06-02
HUP0104465A3 (en) 2002-12-28
PT1133496E (pt) 2004-08-31
RU2247122C2 (ru) 2005-02-27
TR200101438T2 (tr) 2001-10-22
UA67874C2 (uk) 2004-07-15
DE59909262D1 (de) 2004-05-27
SK6822001A3 (en) 2001-12-03
CZ20011858A3 (cs) 2001-09-12

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Legal Events

Date Code Title Description
PC4A Assignment and transfer of rights

Owner name: BAYER INTELLECTUAL PROPERTY GMBH, MONHEIM AM R, DE

Free format text: FORMER OWNER: BAYER ANIMAL HEALTH GMBH, LEVERKUSEN, DE

Effective date: 20121011

MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20121115