SK285004B6 - Použitie (R)-N-[4-(1,4,5,6-tetrahydro-4-metyl-6-oxo-3- pyridazinyl)fenyl]acetamidu na výrobu liečiva - Google Patents

Použitie (R)-N-[4-(1,4,5,6-tetrahydro-4-metyl-6-oxo-3- pyridazinyl)fenyl]acetamidu na výrobu liečiva Download PDF

Info

Publication number
SK285004B6
SK285004B6 SK1873-2000A SK18732000A SK285004B6 SK 285004 B6 SK285004 B6 SK 285004B6 SK 18732000 A SK18732000 A SK 18732000A SK 285004 B6 SK285004 B6 SK 285004B6
Authority
SK
Slovakia
Prior art keywords
oxo
methyl
pyridazinyl
tetrahydro
acetamide
Prior art date
Application number
SK1873-2000A
Other languages
English (en)
Slovak (sk)
Other versions
SK18732000A3 (sk
Inventor
Heimo Haikala
Picro Pollesello
Juha Kaivola
Jouko Levijoki
Original Assignee
Orion Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corporation filed Critical Orion Corporation
Publication of SK18732000A3 publication Critical patent/SK18732000A3/sk
Publication of SK285004B6 publication Critical patent/SK285004B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SK1873-2000A 1998-06-19 1999-05-26 Použitie (R)-N-[4-(1,4,5,6-tetrahydro-4-metyl-6-oxo-3- pyridazinyl)fenyl]acetamidu na výrobu liečiva SK285004B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/099,945 US5905078A (en) 1998-06-19 1998-06-19 Use of a pyridazinone derivative
PCT/FI1999/000449 WO1999066932A1 (en) 1998-06-19 1999-05-26 New use of a pyridazinone derivative

Publications (2)

Publication Number Publication Date
SK18732000A3 SK18732000A3 (sk) 2001-12-03
SK285004B6 true SK285004B6 (sk) 2006-04-06

Family

ID=22277351

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1873-2000A SK285004B6 (sk) 1998-06-19 1999-05-26 Použitie (R)-N-[4-(1,4,5,6-tetrahydro-4-metyl-6-oxo-3- pyridazinyl)fenyl]acetamidu na výrobu liečiva

Country Status (18)

Country Link
US (2) US5905078A (de)
EP (1) EP1087769B1 (de)
JP (1) JP4938928B2 (de)
AT (1) ATE261305T1 (de)
AU (1) AU760379B2 (de)
BR (1) BR9911237A (de)
CA (1) CA2334910C (de)
CZ (1) CZ295283B6 (de)
DE (1) DE69915475T2 (de)
EE (1) EE04658B1 (de)
ES (1) ES2217767T3 (de)
HU (1) HUP0202836A3 (de)
IL (2) IL140032A0 (de)
NZ (1) NZ508444A (de)
PL (1) PL194344B1 (de)
SK (1) SK285004B6 (de)
TR (1) TR200003772T2 (de)
WO (1) WO1999066932A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20011465A0 (fi) * 2001-07-04 2001-07-04 Orion Corp Pyridatsinonijohdannaisen uusi käyttö
FI20040674A0 (fi) 2004-05-12 2004-05-12 Orion Corp Menetelmä tromboembolisten sairauksien estoon
EP1833480A2 (de) * 2004-11-30 2007-09-19 Artesian Therapeutics, Inc. Kardiotonische verbindungen mit hemmwirkung gegen beta-adrenerge rezeptor und phosphodiesterase
TW200920371A (en) 2007-08-29 2009-05-16 Orion Corp A combination treatment
WO2011027021A1 (en) 2009-09-01 2011-03-10 Orion Corporation A method for the treatment of hypertension
US9915301B2 (en) 2010-10-28 2018-03-13 Ford Global Technologies, Llc Magnetically actuated mechanical diode
US8418825B2 (en) 2010-10-28 2013-04-16 Ford Global Technologies, Llc Magnetically actuated mechanical diode
US9366298B2 (en) 2010-10-28 2016-06-14 Ford Global Technologies, Llc Magnetically actuated clutch assembly
WO2021001601A1 (en) 2019-07-01 2021-01-07 Orion Corporation Methods for administering (r)-n-[4-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)phenyl]acetamide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3746712A (en) * 1971-06-08 1973-07-17 A Ross 6-(substituted-phenyl)-5-methyl-4,5-dihydro-3(2h)-pyridazinones
US4397854A (en) * 1981-05-14 1983-08-09 Warner-Lambert Company Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
JPS588015A (ja) * 1981-07-06 1983-01-18 Mitsubishi Chem Ind Ltd 強心剤
JP2921933B2 (ja) * 1989-07-14 1999-07-19 帝国臓器製薬株式会社 光学活性酪酸誘導体
GB2251615B (en) * 1991-01-03 1995-02-08 Orion Yhtymae Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
JP3131845B2 (ja) * 1991-06-12 2001-02-05 帝国臓器製薬株式会社 慢性心不全治療剤
GB9606474D0 (en) * 1996-03-27 1996-06-05 Orion Yhytmo Oy Method for obtaining pure enantiomers of a pyridazinone derivative
JP3163050B2 (ja) 1997-12-25 2001-05-08 三洋電機株式会社 自動洗髪機

Also Published As

Publication number Publication date
USRE38102E1 (en) 2003-04-29
ATE261305T1 (de) 2004-03-15
TR200003772T2 (tr) 2001-06-21
CZ20004554A3 (en) 2001-05-16
PL345036A1 (en) 2001-11-19
HUP0202836A2 (hu) 2003-02-28
DE69915475T2 (de) 2005-03-24
ES2217767T3 (es) 2004-11-01
SK18732000A3 (sk) 2001-12-03
HUP0202836A3 (en) 2003-03-28
NZ508444A (en) 2003-03-28
EP1087769B1 (de) 2004-03-10
EP1087769A1 (de) 2001-04-04
CZ295283B6 (cs) 2005-06-15
DE69915475D1 (de) 2004-04-15
IL140032A (en) 2007-05-15
AU4516699A (en) 2000-01-10
EE04658B1 (et) 2006-08-15
WO1999066932A1 (en) 1999-12-29
BR9911237A (pt) 2001-03-06
US5905078A (en) 1999-05-18
JP2002518450A (ja) 2002-06-25
CA2334910C (en) 2007-10-23
JP4938928B2 (ja) 2012-05-23
IL140032A0 (en) 2002-02-10
EE200000755A (et) 2002-04-15
AU760379B2 (en) 2003-05-15
PL194344B1 (pl) 2007-05-31
CA2334910A1 (en) 1999-12-29

Similar Documents

Publication Publication Date Title
JP2845913B2 (ja) 緑内障、水頭症、および脳水腫（頭蓋液量異常）治療用のアトリオペプチン、グアニル酸シクラーゼ賦活物質、およびホスホジエステラーゼ阻害物質
US5968911A (en) Method of inducing vasorelaxation to treat pulmonary hypertension
JP3875261B2 (ja) 求核剤／酸化窒素・複合体およびその誘導体による血小板凝集の治療的阻害
ES2210562T3 (es) Preparaciones que sirven para la prevencion y el tratamiento de enfermedades provocadas por una hipofuncion del oxido nitrico sintasa.
KR20010053252A (ko) ＣＯＸ-2 억제제 및 ｉＮＯＳ 억제제를 포함하는 제약 제제
JPH09505288A (ja) 酸化窒素合成の誘導をブロックするためのテトラヒドロビオプテリンのブロッキング誘導
SK285004B6 (sk) Použitie (R)-N-[4-(1,4,5,6-tetrahydro-4-metyl-6-oxo-3- pyridazinyl)fenyl]acetamidu na výrobu liečiva
JP2017193553A (ja) 神経線維腫症の処置のためのピリミジルアミノベンズアミド誘導体
SK13232002A3 (sk) Použitie pyrido[3,2-e]-pyrazinónov ako inhibítorov fosfodiesterázy 5 na liečbu erektilnej dysfunkcie
JP2024506657A (ja) Ｉｒａｋ４分解剤およびその使用
RU2130019C1 (ru) Производные 3(2н)-пиридазинона, фармацевтическая композиция, способ лечения
KR20010032009A (ko) 수면성 무호흡의 치료에 미타자핀을 사용하는 방법
MCAULEY et al. Intracavernosal sildenafil facilitates penile erection independent of the nitric oxide pathway
JPH03209322A (ja) ピリミドン誘導体及び類似化合物を含有するある種の皮膚疾患の局所投与治療用医薬組成物
US6465465B1 (en) Process for the treatment of erectile dysfunction and product therefor
JP5154408B2 (ja) 好酸球増加症候群のためのピリミジルアミノベンズアミド誘導体
JP2009504674A (ja) 有機化合物の組合せ
JPS62289525A (ja) カルシウム調節活性を有する化合物及び製薬組成物
US4975428A (en) Treatment of glaucoma using phosphodiesterase inhibitors
CZARNECKI et al. Mechanism of the inotropic action of inosine on canine myocardium
US4153700A (en) Treatment of the acute after-effects resulting from alcohol ingestion
JP2002275096A (ja) 併用療法
Bergren et al. Rapidly-adapting receptor activity and intratracheal pressure in guinea pigs I. Action of leukotriene C4
US5200405A (en) Use of n-(1-hexahydroazepinylalkyl) acetamides for the treatment of cholinergic transmission disorders
US20030032655A1 (en) Heme oxygenase-1 inducers or induction enhancers

Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20130526