SK284598B6 - Oligonukleotidové konjugáty, spôsob detekcie cieľovej štruktúry, použitie týchto zlúčenín a diagnostický kit - Google Patents

Oligonukleotidové konjugáty, spôsob detekcie cieľovej štruktúry, použitie týchto zlúčenín a diagnostický kit Download PDF

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Publication number
SK284598B6
SK284598B6 SK28-97A SK2897A SK284598B6 SK 284598 B6 SK284598 B6 SK 284598B6 SK 2897 A SK2897 A SK 2897A SK 284598 B6 SK284598 B6 SK 284598B6
Authority
SK
Slovakia
Prior art keywords
groups
oligonucleotide
oligonucleotides
group
acid
Prior art date
Application number
SK28-97A
Other languages
English (en)
Slovak (sk)
Other versions
SK2897A3 (en
Inventor
Ludger Dinkelborg
Christoph-Stephan Hilger
Ulrich Niedballa
Johannes Platzek
Bernd Rad�Chel
Ulrich Speck
Larry Gold
Wolfgang Pieken
Original Assignee
Schering Ag
Nexstar Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25938359&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK284598(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE4424922A external-priority patent/DE4424922A1/de
Priority claimed from DE19944445078 external-priority patent/DE4445078A1/de
Application filed by Schering Ag, Nexstar Pharmaceuticals, Inc. filed Critical Schering Ag
Publication of SK2897A3 publication Critical patent/SK2897A3/sk
Publication of SK284598B6 publication Critical patent/SK284598B6/sk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
SK28-97A 1994-07-14 1995-06-30 Oligonukleotidové konjugáty, spôsob detekcie cieľovej štruktúry, použitie týchto zlúčenín a diagnostický kit SK284598B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4424922A DE4424922A1 (de) 1994-07-14 1994-07-14 Konjugate aus Metallkomplexen und Oligonucleotiden, die spezifisch an bestimmte Zielstrukturen binden
DE19944445078 DE4445078A1 (de) 1994-12-05 1994-12-05 Konjugate aus Metallkomplexen und Oligonucleotiden, diese enthaltende Mittel, deren Verwendung in der Radiodiagnostik sowie Verfahren zu deren Herstellung
PCT/EP1995/002539 WO1996002274A1 (en) 1994-07-14 1995-06-30 Conjugates made of metal complexes and oligonucleotides

Publications (2)

Publication Number Publication Date
SK2897A3 SK2897A3 (en) 1997-09-10
SK284598B6 true SK284598B6 (sk) 2005-07-01

Family

ID=25938359

Family Applications (1)

Application Number Title Priority Date Filing Date
SK28-97A SK284598B6 (sk) 1994-07-14 1995-06-30 Oligonukleotidové konjugáty, spôsob detekcie cieľovej štruktúry, použitie týchto zlúčenín a diagnostický kit

Country Status (23)

Country Link
EP (1) EP0777498B1 (cs)
JP (2) JPH10503182A (cs)
KR (1) KR100366525B1 (cs)
CN (1) CN1219551C (cs)
AT (1) ATE265229T1 (cs)
AU (1) AU2979195A (cs)
CA (1) CA2194558A1 (cs)
CZ (1) CZ295930B6 (cs)
DE (1) DE69532958T2 (cs)
DK (1) DK0777498T3 (cs)
ES (1) ES2220933T3 (cs)
HU (1) HU220859B1 (cs)
IL (1) IL114237A (cs)
MX (1) MX9606443A (cs)
NO (1) NO318585B1 (cs)
NZ (1) NZ289831A (cs)
PL (1) PL318147A1 (cs)
PT (1) PT777498E (cs)
RU (1) RU2165771C2 (cs)
SK (1) SK284598B6 (cs)
TW (1) TW502040B (cs)
UA (1) UA48140C2 (cs)
WO (1) WO1996002274A1 (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2259493A1 (en) * 1996-07-03 1998-01-08 President And Fellows Of Harvard College Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides
US6335437B1 (en) * 1998-09-07 2002-01-01 Isis Pharmaceuticals, Inc. Methods for the preparation of conjugated oligomers
JP2009535383A (ja) * 2006-05-03 2009-10-01 バルティック テクロノジー デヴェロプメント，リミテッド 強く結合した塩基で修飾されたオリゴヌクレオチドと人工ヌクレアーゼを組み合わせたアンチセンス作用物質
GB201012418D0 (en) * 2010-07-23 2010-09-08 Santaris Pharma As Process
KR101948404B1 (ko) 2014-05-13 2019-02-14 폴 슈레 앙스띠뛰 양전자 방출 단층촬영에 사용하기 위한 43sc 방사성핵종 및 그의 방사성제약의 제조

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013831A (en) * 1984-01-30 1991-05-07 Enzo Biochem, Inc. Detectable molecules, method of preparation and use
JP2785025B2 (ja) * 1985-03-19 1998-08-13 ランデル・エル・ミルズ 診断と選択的組織壊死を与える装置
US5057302A (en) * 1987-02-13 1991-10-15 Abbott Laboratories Bifunctional chelating agents
WO1989000062A1 (en) * 1987-07-07 1989-01-12 The Cancer Institute Board Radiotherapy
US5457183A (en) * 1989-03-06 1995-10-10 Board Of Regents, The University Of Texas System Hydroxylated texaphyrins
EP1493825A3 (en) * 1990-06-11 2005-02-09 Gilead Sciences, Inc. Method for producing nucleic acid ligands
US5270163A (en) * 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
IE914220A1 (en) * 1990-12-10 1992-06-17 Akzo Nv Labelled, modified oligonucleotides
EP0588229A3 (en) * 1992-09-12 1994-06-15 Hoechst Ag Macrocyclic chelating agents for the preparation of technetium or rhenium complexes

Also Published As

Publication number Publication date
DE69532958T2 (de) 2009-04-09
PT777498E (pt) 2004-09-30
EP0777498A1 (en) 1997-06-11
KR970704471A (ko) 1997-09-06
JPH10503182A (ja) 1998-03-24
RU2165771C2 (ru) 2001-04-27
DK0777498T3 (da) 2004-08-16
TW502040B (en) 2002-09-11
NO970141D0 (no) 1997-01-13
CZ11497A3 (cs) 1998-08-12
UA48140C2 (uk) 2002-08-15
ATE265229T1 (de) 2004-05-15
HU9700100D0 (en) 1997-02-28
JP2009197024A (ja) 2009-09-03
IL114237A0 (en) 1995-10-31
IL114237A (en) 2000-08-31
CZ295930B6 (cs) 2005-12-14
MX9606443A (es) 1997-12-31
KR100366525B1 (ko) 2003-03-15
CN1152879A (zh) 1997-06-25
EP0777498B1 (en) 2004-04-28
NO970141L (no) 1997-03-14
HU220859B1 (en) 2002-06-29
PL318147A1 (en) 1997-05-12
NO318585B1 (no) 2005-04-11
NZ289831A (en) 1999-01-28
CN1219551C (zh) 2005-09-21
WO1996002274A1 (en) 1996-02-01
ES2220933T3 (es) 2004-12-16
SK2897A3 (en) 1997-09-10
DE69532958D1 (de) 2004-06-03
AU2979195A (en) 1996-02-16
CA2194558A1 (en) 1996-02-01
HUT76329A (en) 1997-08-28

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20100630