SK281051B6 - Derivát alkylbenzolguanidínu, spôsob jeho prípravy, jeho použitie a farmaceutický prostriedok, ktorý ho obsahuje - Google Patents
Derivát alkylbenzolguanidínu, spôsob jeho prípravy, jeho použitie a farmaceutický prostriedok, ktorý ho obsahuje Download PDFInfo
- Publication number
- SK281051B6 SK281051B6 SK1055-95A SK105595A SK281051B6 SK 281051 B6 SK281051 B6 SK 281051B6 SK 105595 A SK105595 A SK 105595A SK 281051 B6 SK281051 B6 SK 281051B6
- Authority
- SK
- Slovakia
- Prior art keywords
- diaminomethylene
- methylsulfonyl
- methyl ester
- methylsulfonylbenzamide
- ethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4430916A DE4430916A1 (de) | 1994-08-31 | 1994-08-31 | Alkyl-benzoylguanidin-Derivate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK105595A3 SK105595A3 (en) | 1996-03-06 |
| SK281051B6 true SK281051B6 (sk) | 2000-11-07 |
Family
ID=6527018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1055-95A SK281051B6 (sk) | 1994-08-31 | 1995-08-25 | Derivát alkylbenzolguanidínu, spôsob jeho prípravy, jeho použitie a farmaceutický prostriedok, ktorý ho obsahuje |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5840761A (uk) |
| EP (1) | EP0699663B1 (uk) |
| JP (1) | JP3732873B2 (uk) |
| KR (1) | KR100406687B1 (uk) |
| CN (1) | CN1055920C (uk) |
| AT (1) | ATE172962T1 (uk) |
| AU (1) | AU701558B2 (uk) |
| BR (1) | BR9503854A (uk) |
| CA (1) | CA2157143C (uk) |
| CZ (1) | CZ288015B6 (uk) |
| DE (2) | DE4430916A1 (uk) |
| ES (1) | ES2126190T3 (uk) |
| HU (1) | HU222401B1 (uk) |
| NO (1) | NO305901B1 (uk) |
| PL (1) | PL180902B1 (uk) |
| RU (1) | RU2142940C1 (uk) |
| SK (1) | SK281051B6 (uk) |
| TW (1) | TW397814B (uk) |
| UA (1) | UA41353C2 (uk) |
| ZA (1) | ZA957283B (uk) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4328352A1 (de) * | 1993-08-24 | 1995-03-02 | Hoechst Ag | Substituierte N,N'-Di-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19517848A1 (de) * | 1995-05-16 | 1996-11-21 | Merck Patent Gmbh | Fluorhaltige Benzoylguanidine |
| DE19529612A1 (de) * | 1995-08-11 | 1997-02-13 | Merck Patent Gmbh | Sulfonyl- oder Sulfinyl-benzoylguanidin-Derivate |
| DE19531138A1 (de) * | 1995-08-24 | 1997-02-27 | Merck Patent Gmbh | Alkenyl-benzoylguanidin-Derivate |
| CA2195697A1 (en) * | 1996-02-02 | 1997-08-03 | Masahumi Kitano | Novel substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof |
| DE19624178A1 (de) * | 1996-06-18 | 1998-01-08 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| ID29523A (id) * | 1998-11-26 | 2001-09-06 | Marck Patent Gmbh | Penggunaan benzoilgunidin-benzoilguanidin untuk pengobatan diabetes melitus yang tidak bergantung pada insulin |
| DE10001879A1 (de) * | 2000-01-19 | 2001-07-19 | Aventis Pharma Gmbh | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE60329030D1 (de) * | 2002-12-04 | 2009-10-08 | Ore Pharmaceuticals Inc | Melanocortin-rezeptormodulatoren |
| KR20060015580A (ko) * | 2003-05-06 | 2006-02-17 | 메르크 파텐트 게엠베하 | 구아니디늄 염의 결정화 방법 |
| USD781236S1 (en) | 2016-01-14 | 2017-03-14 | Premier Accessory Group LLC | Charging device |
| WO2018058109A1 (en) | 2016-09-26 | 2018-03-29 | Nusirt Sciences, Inc. | Compositions and methods for treating metabolic disorders |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3929582A1 (de) | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
| EP0556673B1 (de) * | 1992-02-15 | 1997-09-17 | Hoechst Aktiengesellschaft | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| CZ284456B6 (cs) * | 1992-02-15 | 1998-12-16 | Hoechst Aktiengesellschaft | Aminosubstituované benzoylguanidiny, způsob jejich přípravy, jejich použití jako léčiv a léčivo, které je obsahuje |
| ATE139526T1 (de) * | 1992-02-15 | 1996-07-15 | Hoechst Ag | 3,5-substituierte benzoylguanidine, mit antiarrythmischer wirkung und inhibierender wirkung auf die proliferationen von zellen |
| DE59304166D1 (de) * | 1992-07-01 | 1996-11-21 | Hoechst Ag | 3,4,5-Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| ATE147375T1 (de) * | 1992-09-22 | 1997-01-15 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, sowie ihre verwendung als antiarrhythmika |
| TW250479B (uk) * | 1992-12-15 | 1995-07-01 | Hoechst Ag | |
| DE59306029D1 (de) * | 1992-12-16 | 1997-05-07 | Hoechst Ag | 3,5-Substituierte Aminobenzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| MY128187A (en) * | 1993-06-23 | 2007-01-31 | Icn Switzerland Ag | Preparation for skin and mucous membrane |
| DE4328869A1 (de) * | 1993-08-27 | 1995-03-02 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4417004A1 (de) * | 1994-05-13 | 1995-11-16 | Hoechst Ag | Perfluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1994
- 1994-08-31 DE DE4430916A patent/DE4430916A1/de not_active Withdrawn
-
1995
- 1995-07-25 TW TW084107704A patent/TW397814B/zh active
- 1995-08-21 AT AT95113104T patent/ATE172962T1/de not_active IP Right Cessation
- 1995-08-21 DE DE59504122T patent/DE59504122D1/de not_active Expired - Lifetime
- 1995-08-21 ES ES95113104T patent/ES2126190T3/es not_active Expired - Lifetime
- 1995-08-21 EP EP95113104A patent/EP0699663B1/de not_active Expired - Lifetime
- 1995-08-23 UA UA95083917A patent/UA41353C2/uk unknown
- 1995-08-24 AU AU30251/95A patent/AU701558B2/en not_active Ceased
- 1995-08-25 HU HU9502501A patent/HU222401B1/hu not_active IP Right Cessation
- 1995-08-25 SK SK1055-95A patent/SK281051B6/sk unknown
- 1995-08-29 CA CA002157143A patent/CA2157143C/en not_active Expired - Fee Related
- 1995-08-29 CZ CZ19952203A patent/CZ288015B6/cs not_active IP Right Cessation
- 1995-08-30 RU RU95114673A patent/RU2142940C1/ru not_active IP Right Cessation
- 1995-08-30 BR BR9503854A patent/BR9503854A/pt active Search and Examination
- 1995-08-30 PL PL95310225A patent/PL180902B1/pl not_active IP Right Cessation
- 1995-08-30 NO NO953405A patent/NO305901B1/no not_active IP Right Cessation
- 1995-08-30 CN CN95116672A patent/CN1055920C/zh not_active Expired - Fee Related
- 1995-08-30 ZA ZA957283A patent/ZA957283B/xx unknown
- 1995-08-30 US US08/520,767 patent/US5840761A/en not_active Expired - Lifetime
- 1995-08-31 KR KR1019950027958A patent/KR100406687B1/ko not_active IP Right Cessation
- 1995-08-31 JP JP24515295A patent/JP3732873B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO953405L (no) | 1996-03-01 |
| CZ288015B6 (cs) | 2001-04-11 |
| HU9502501D0 (en) | 1995-10-30 |
| DE4430916A1 (de) | 1996-03-07 |
| PL180902B1 (pl) | 2001-04-30 |
| CA2157143C (en) | 2009-02-17 |
| US5840761A (en) | 1998-11-24 |
| JPH08188568A (ja) | 1996-07-23 |
| CZ220395A3 (en) | 1996-03-13 |
| AU701558B2 (en) | 1999-01-28 |
| NO305901B1 (no) | 1999-08-16 |
| CA2157143A1 (en) | 1996-03-01 |
| BR9503854A (pt) | 1996-09-17 |
| NO953405D0 (no) | 1995-08-30 |
| EP0699663A1 (de) | 1996-03-06 |
| UA41353C2 (uk) | 2001-09-17 |
| EP0699663B1 (de) | 1998-11-04 |
| CN1055920C (zh) | 2000-08-30 |
| CN1128753A (zh) | 1996-08-14 |
| JP3732873B2 (ja) | 2006-01-11 |
| AU3025195A (en) | 1996-02-15 |
| KR960007538A (ko) | 1996-03-22 |
| KR100406687B1 (ko) | 2004-07-19 |
| ES2126190T3 (es) | 1999-03-16 |
| SK105595A3 (en) | 1996-03-06 |
| HUT75094A (en) | 1997-04-28 |
| TW397814B (en) | 2000-07-11 |
| ATE172962T1 (de) | 1998-11-15 |
| PL310225A1 (en) | 1996-03-04 |
| RU2142940C1 (ru) | 1999-12-20 |
| DE59504122D1 (de) | 1998-12-10 |
| ZA957283B (en) | 1996-04-02 |
| HU222401B1 (hu) | 2003-06-28 |
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