SK280742B6 - R(+)-n-propargyl-1-aminoindán, spôsob jeho príprav - Google Patents
R(+)-n-propargyl-1-aminoindán, spôsob jeho príprav Download PDFInfo
- Publication number
- SK280742B6 SK280742B6 SK6-91A SK691A SK280742B6 SK 280742 B6 SK280742 B6 SK 280742B6 SK 691 A SK691 A SK 691A SK 280742 B6 SK280742 B6 SK 280742B6
- Authority
- SK
- Slovakia
- Prior art keywords
- propargyl
- aminoindan
- mao
- pai
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/30—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
- C07C211/41—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
- C07C211/42—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL9295290A IL92952A (en) | 1990-01-03 | 1990-01-03 | R-enantiomers of n-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
SK280742B6 true SK280742B6 (sk) | 2000-07-11 |
Family
ID=11060756
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK6-91A SK280742B6 (sk) | 1990-01-03 | 1991-01-03 | R(+)-n-propargyl-1-aminoindán, spôsob jeho príprav |
Country Status (20)
Country | Link |
---|---|
US (10) | US5387612A (de) |
EP (1) | EP0436492B1 (de) |
JP (1) | JP2987453B2 (de) |
AT (1) | ATE106860T1 (de) |
AU (1) | AU630772B2 (de) |
CA (1) | CA2031714C (de) |
CZ (1) | CZ288222B6 (de) |
DE (2) | DE69102288T2 (de) |
DK (1) | DK0436492T3 (de) |
ES (1) | ES2057604T3 (de) |
HK (1) | HK1008017A1 (de) |
HU (1) | HU215451B (de) |
IE (1) | IE62371B1 (de) |
IL (1) | IL92952A (de) |
LU (1) | LU91195I2 (de) |
NL (1) | NL300206I1 (de) |
RO (1) | RO107552B1 (de) |
RU (1) | RU2001614C1 (de) |
SK (1) | SK280742B6 (de) |
ZA (1) | ZA909997B (de) |
Families Citing this family (123)
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US5914349A (en) * | 1994-01-10 | 1999-06-22 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives |
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GEP20012374B (en) * | 1995-03-02 | 2001-03-25 | Scherer Ltd R P | Pharmaceutical Compositions Comprising Monoamine Oxidase B Inhibitors, Method for Obtaining the Same and Use |
US5679715A (en) * | 1995-06-07 | 1997-10-21 | Harris; Richard Y. | Method for treating multiple sclerosis |
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IL115357A (en) * | 1995-09-20 | 2000-01-31 | Teva Pharma | Stable compositions containing N-propargyl-1-aminoindan and polyhydric alcohols |
IL118836A (en) * | 1996-07-11 | 2001-01-11 | Teva Pharma | Pharmaceutical compositions comprising s-(-)-n-propargyl-1-aminoindan |
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US3201470A (en) * | 1965-08-17 | Chsx c cech | ||
FR1366728A (fr) * | 1961-03-01 | 1964-07-17 | Roussel Uclaf | Nouveaux dérivés du gonane et leur procédé de préparation |
US3253037A (en) * | 1962-06-19 | 1966-05-24 | Ciba Geigy Corp | N-2-alkynyl-amino-benzocylo-alkanes |
GB1037014A (en) * | 1963-08-02 | 1966-07-20 | Aspro Nicholas Ltd | Derivatives of 1-aminoindane |
GB1187017A (en) * | 1966-07-16 | 1970-04-08 | Aspro Nicholas Ltd | Substituted 1-Amino Indanes and Tetrahydronaphthalens |
US3513249A (en) * | 1968-12-24 | 1970-05-19 | Ideal Ind | Explosion connector with improved insulating means |
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IL92952A (en) * | 1990-01-03 | 1994-06-24 | Teva Pharma | R-enantiomers of n-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them |
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1990
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- 1990-12-28 JP JP2409285A patent/JP2987453B2/ja not_active Expired - Lifetime
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1991
- 1991-01-02 DE DE69102288T patent/DE69102288T2/de not_active Expired - Lifetime
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- 1991-01-03 SK SK6-91A patent/SK280742B6/sk not_active IP Right Cessation
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1993
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- 1994-07-14 DE DE200512000045 patent/DE122005000045I1/de active Pending
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1995
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1998
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Legal Events
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MK4A | Patent expired |
Expiry date: 20110103 |
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SPCT | Transfer of rights of an spc |
Owner name: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. Free format text: PREVIOUS OWNERS: TEVA PHARMACEUTICAL INDUSTRIES LTD., PETAH-TIKVA, IL; TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD., HAIFA, IL; PRODUCT NAME: RASAGILIN MESILA; REGISTRATION NO/DATE: EU/1/04/304/001-007 20050221 Spc suppl protection certif: 32 5004-2004 Filing date: 20050819 Extension date: 20160104 Effective date: 20110627 |
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Free format text: PRODUCT NAME: ASAGILIN MESILAT; REGISTRATION NO/DATE: EU/1/04/304/001-007, 21.02.2005 Spc suppl protection certif: 32 5004-2005 Expiry date: 20160104 |