SK279918B6 - Soli kyseliny klavulánovej s diamínmi, spôsob ich - Google Patents

Soli kyseliny klavulánovej s diamínmi, spôsob ich Download PDF

Info

Publication number
SK279918B6
SK279918B6 SK1442-94A SK144294A SK279918B6 SK 279918 B6 SK279918 B6 SK 279918B6 SK 144294 A SK144294 A SK 144294A SK 279918 B6 SK279918 B6 SK 279918B6
Authority
SK
Slovakia
Prior art keywords
clavulanic acid
salts
alkyl
diamine
diamines
Prior art date
Application number
SK1442-94A
Other languages
English (en)
Slovak (sk)
Other versions
SK144294A3 (en
Inventor
Pieter G. Weber
Original Assignee
Gist-Brocades N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist-Brocades N.V. filed Critical Gist-Brocades N.V.
Publication of SK144294A3 publication Critical patent/SK144294A3/sk
Publication of SK279918B6 publication Critical patent/SK279918B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D503/00Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pyrrole Compounds (AREA)
SK1442-94A 1993-03-26 1994-03-22 Soli kyseliny klavulánovej s diamínmi, spôsob ich SK279918B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP93200872 1993-03-26
PCT/EP1994/000919 WO1994022873A1 (en) 1993-03-26 1994-03-22 Diamine salts of clavulanic acid
US08/457,985 US5719277A (en) 1993-03-26 1995-06-01 Diamine salts of clavulanic acid

Publications (2)

Publication Number Publication Date
SK144294A3 SK144294A3 (en) 1995-06-07
SK279918B6 true SK279918B6 (sk) 1999-05-07

Family

ID=26133724

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1442-94A SK279918B6 (sk) 1993-03-26 1994-03-22 Soli kyseliny klavulánovej s diamínmi, spôsob ich

Country Status (22)

Country Link
US (1) US5719277A (zh)
EP (2) EP0719778A1 (zh)
CN (1) CN1041933C (zh)
AT (1) ATE140703T1 (zh)
AU (1) AU682030B2 (zh)
CA (1) CA2135671A1 (zh)
CY (1) CY1966A (zh)
CZ (1) CZ284855B6 (zh)
DE (2) DE647229T1 (zh)
DK (1) DK0647229T3 (zh)
ES (1) ES2070109T3 (zh)
FI (1) FI945510A0 (zh)
HK (1) HK217196A (zh)
HU (1) HUT69372A (zh)
IL (1) IL109139A (zh)
NO (1) NO301767B1 (zh)
NZ (1) NZ263564A (zh)
PL (1) PL306371A1 (zh)
RO (1) RO112113B1 (zh)
SK (1) SK279918B6 (zh)
WO (1) WO1994022873A1 (zh)
ZA (1) ZA942133B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT399155B (de) * 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
GB2282810B (en) * 1992-06-11 1997-02-26 Smithkline Beecham Plc Preparation or purification of clavulanic acid
SI9300296B (sl) * 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
AU678752B3 (en) * 1992-06-11 1997-06-05 Smithkline Beecham Plc Process for the preparation of clavulanic acid
SI9400107A (en) * 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts
EP0729961B1 (en) * 1995-02-25 2001-12-19 Spurcourt Limited Clavulanic acid salt
SI9500134B (sl) 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
SI9500265A1 (en) 1995-08-28 1997-02-28 Lek Tovarna Farmacevtskih Process for purification of the aqueous fermented broth filtrate of streptomyces sp. p 6621 ferm p 2804 by ultrafiltration
US6071532A (en) * 1996-10-15 2000-06-06 Emory University Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof
EP1095046A1 (en) * 1998-07-16 2001-05-02 Dsm N.V. Improved process for the preparation of salts and esters of clavulanic acid
US6908663B1 (en) * 2000-11-15 2005-06-21 Awi Licensing Company Pigmented radiation cured wear layer
CN105384758B (zh) * 2015-12-01 2018-05-01 国药集团威奇达药业有限公司 克拉维酸胺盐的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE41109B1 (en) * 1974-04-20 1979-10-24 Beecham Group Ltd Novel -lactam antibiotic from streptomyces clavuligerus
EP0026044B1 (en) * 1979-08-24 1983-06-08 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
ES2010143A6 (es) * 1989-03-01 1989-10-16 Pharma Mar S A Pharmar Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp.
AT399155B (de) * 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) * 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
GB9305565D0 (en) * 1993-03-18 1993-05-05 Smithkline Beecham Plc Novel compounds and processes

Also Published As

Publication number Publication date
ES2070109T3 (es) 1996-12-01
DE69400334D1 (de) 1996-08-29
FI945510A (fi) 1994-11-23
NO301767B1 (no) 1997-12-08
DE69400334T2 (de) 1997-02-13
HUT69372A (en) 1995-09-28
EP0719778A1 (en) 1996-07-03
EP0647229B1 (en) 1996-07-24
FI945510A0 (fi) 1994-11-23
NO944531D0 (no) 1994-11-25
SK144294A3 (en) 1995-06-07
PL306371A1 (en) 1995-03-20
CY1966A (en) 1997-07-04
AU6429494A (en) 1994-10-24
HU9403383D0 (en) 1995-02-28
CZ286394A3 (en) 1995-03-15
ATE140703T1 (de) 1996-08-15
DE647229T1 (de) 1996-01-18
EP0647229A1 (en) 1995-04-12
IL109139A (en) 1997-03-18
IL109139A0 (en) 1994-06-24
CA2135671A1 (en) 1994-10-13
HK217196A (en) 1996-12-27
NO944531L (no) 1994-11-25
WO1994022873A1 (en) 1994-10-13
ES2070109T1 (es) 1995-06-01
RO112113B1 (ro) 1997-05-30
DK0647229T3 (da) 1996-10-07
US5719277A (en) 1998-02-17
ZA942133B (en) 1995-02-21
AU682030B2 (en) 1997-09-18
CN1041933C (zh) 1999-02-03
CN1108029A (zh) 1995-09-06
NZ263564A (en) 1995-12-21
CZ284855B6 (cs) 1999-03-17

Similar Documents

Publication Publication Date Title
SK279918B6 (sk) Soli kyseliny klavulánovej s diamínmi, spôsob ich
CH640862A5 (de) Verfahren zur herstellung neuer hydroxylamin-substituierter aliphatischer phosphonsaeuren.
CH622262A5 (zh)
CA2105556A1 (en) Insect control with substituted oxadiazole and thiadiazole compounds
SK111197A3 (en) Clavulanic acid salts
RU2152948C1 (ru) Диклавулановая соль диаминового эфира и способ ее приготовления
DE69500274T2 (de) Thiazin- oder Thiomorpholinderivate
SU1322983A3 (ru) Способ получени производных цефалоспорина в виде их аддитивных солей с сол ной кислотой
SE8406517L (sv) Alkyloximsubstituerade 7-(2-amino-4-tiazolyl)-acetamido-cefalosporansyraderivat, framstellning och anvendning derav sasom lekemedel samt kompositioner innehallande dessa foreningar
RU1820909C (ru) Способ получени производных амида 4-оксо-4Н-пиридо /1,2- @ /пиримидин-3-карбоновой кислоты или их кислотно-аддитивных солей
EP0183174B1 (en) Substituted phenoxy urea, processes for its preparation and herbicide containing it as active ingredient
US5821364A (en) Diamine salts of clavulanic acid
DE3531453A1 (de) Substituierte 7-oxomitosan-verbindungen, verfahren zu deren herstellung und diese verbindungen enthaltende, pharmazeutische mittel
US5741903A (en) Diamine salts for purification of clavulanic acid
RU2135502C1 (ru) Диаминовые соли клавулановой кислоты, способ их получения (варианты), способ получения клавулановой кислоты или ее фармацевтически приемлемой соли, способ очистки клавулановой кислоты или ее соли
US5760218A (en) Diamine salts of clavulanic acid
US5098919A (en) Pyrrolo(2,1-b)thiazole derivatives
SU1052159A3 (ru) Способ получени производных 7-/2-(2-аминотиазолил)-2-оксииминоацетамидо/- 3-цефем-4-карбоновых кислот или их сложных эфиров или их фармацевтически приемлемых солей
RU97115880A (ru) Соли клавулановой кислоты