DE647229T1 - Diaminsalze von clavulansäure. - Google Patents

Diaminsalze von clavulansäure.

Info

Publication number
DE647229T1
DE647229T1 DE0647229T DE94911952T DE647229T1 DE 647229 T1 DE647229 T1 DE 647229T1 DE 0647229 T DE0647229 T DE 0647229T DE 94911952 T DE94911952 T DE 94911952T DE 647229 T1 DE647229 T1 DE 647229T1
Authority
DE
Germany
Prior art keywords
clavulanic acid
diamine salts
salts
diamine
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE0647229T
Other languages
English (en)
Inventor
Pieter Weber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gist Brocades NV
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Publication of DE647229T1 publication Critical patent/DE647229T1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pyrrole Compounds (AREA)
DE0647229T 1993-03-26 1994-03-22 Diaminsalze von clavulansäure. Pending DE647229T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP93200872 1993-03-26
PCT/EP1994/000919 WO1994022873A1 (en) 1993-03-26 1994-03-22 Diamine salts of clavulanic acid
US08/457,985 US5719277A (en) 1993-03-26 1995-06-01 Diamine salts of clavulanic acid

Publications (1)

Publication Number Publication Date
DE647229T1 true DE647229T1 (de) 1996-01-18

Family

ID=26133724

Family Applications (2)

Application Number Title Priority Date Filing Date
DE0647229T Pending DE647229T1 (de) 1993-03-26 1994-03-22 Diaminsalze von clavulansäure.
DE69400334T Expired - Fee Related DE69400334T2 (de) 1993-03-26 1994-03-22 Diaminsalze von clavulansäure

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69400334T Expired - Fee Related DE69400334T2 (de) 1993-03-26 1994-03-22 Diaminsalze von clavulansäure

Country Status (22)

Country Link
US (1) US5719277A (de)
EP (2) EP0719778A1 (de)
CN (1) CN1041933C (de)
AT (1) ATE140703T1 (de)
AU (1) AU682030B2 (de)
CA (1) CA2135671A1 (de)
CY (1) CY1966A (de)
CZ (1) CZ284855B6 (de)
DE (2) DE647229T1 (de)
DK (1) DK0647229T3 (de)
ES (1) ES2070109T3 (de)
FI (1) FI945510A0 (de)
HK (1) HK217196A (de)
HU (1) HUT69372A (de)
IL (1) IL109139A (de)
NO (1) NO301767B1 (de)
NZ (1) NZ263564A (de)
PL (1) PL306371A1 (de)
RO (1) RO112113B1 (de)
SK (1) SK279918B6 (de)
WO (1) WO1994022873A1 (de)
ZA (1) ZA942133B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT399155B (de) * 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) * 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
GB2282810B (en) * 1992-06-11 1997-02-26 Smithkline Beecham Plc Preparation or purification of clavulanic acid
AU678752B3 (en) * 1992-06-11 1997-06-05 Smithkline Beecham Plc Process for the preparation of clavulanic acid
SI9400107A (en) 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts
PL321871A1 (en) * 1995-02-25 1997-12-22 Spurcourt Ltd Clavulanic salts and compositions containing them as well as method of obtaining such salts
SI9500134B (sl) 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
SI9500265A1 (en) 1995-08-28 1997-02-28 Lek Tovarna Farmacevtskih Process for purification of the aqueous fermented broth filtrate of streptomyces sp. p 6621 ferm p 2804 by ultrafiltration
US6071532A (en) * 1996-10-15 2000-06-06 Emory University Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof
EP1095046A1 (de) * 1998-07-16 2001-05-02 Dsm N.V. Verbessertes verfahren zur herstellung von clavulansäure-salzen und -estern
US6908663B1 (en) * 2000-11-15 2005-06-21 Awi Licensing Company Pigmented radiation cured wear layer
CN105384758B (zh) * 2015-12-01 2018-05-01 国药集团威奇达药业有限公司 克拉维酸胺盐的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE41109B1 (en) * 1974-04-20 1979-10-24 Beecham Group Ltd Novel -lactam antibiotic from streptomyces clavuligerus
DE3063683D1 (en) * 1979-08-24 1983-07-14 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
ES2010143A6 (es) * 1989-03-01 1989-10-16 Pharma Mar S A Pharmar Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp.
AT399155B (de) * 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) * 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
GB9305565D0 (en) * 1993-03-18 1993-05-05 Smithkline Beecham Plc Novel compounds and processes

Also Published As

Publication number Publication date
CA2135671A1 (en) 1994-10-13
SK144294A3 (en) 1995-06-07
IL109139A (en) 1997-03-18
DE69400334T2 (de) 1997-02-13
NO944531L (no) 1994-11-25
DK0647229T3 (da) 1996-10-07
NO944531D0 (no) 1994-11-25
ES2070109T3 (es) 1996-12-01
CN1041933C (zh) 1999-02-03
NO301767B1 (no) 1997-12-08
PL306371A1 (en) 1995-03-20
RO112113B1 (ro) 1997-05-30
FI945510A (fi) 1994-11-23
AU6429494A (en) 1994-10-24
DE69400334D1 (de) 1996-08-29
SK279918B6 (sk) 1999-05-07
EP0647229B1 (de) 1996-07-24
HU9403383D0 (en) 1995-02-28
NZ263564A (en) 1995-12-21
AU682030B2 (en) 1997-09-18
ES2070109T1 (es) 1995-06-01
CY1966A (en) 1997-07-04
ZA942133B (en) 1995-02-21
ATE140703T1 (de) 1996-08-15
IL109139A0 (en) 1994-06-24
EP0719778A1 (de) 1996-07-03
EP0647229A1 (de) 1995-04-12
CZ284855B6 (cs) 1999-03-17
HUT69372A (en) 1995-09-28
CN1108029A (zh) 1995-09-06
HK217196A (en) 1996-12-27
CZ286394A3 (en) 1995-03-15
FI945510A0 (fi) 1994-11-23
US5719277A (en) 1998-02-17
WO1994022873A1 (en) 1994-10-13

Similar Documents

Publication Publication Date Title
DK0490823T3 (de)
ATE103914T1 (de) Neue thienylcarbonsaeureester von aminoalkoholen, ihre quaternierungsprodukte sowie die herstellung und verwendung dieser verbindungen.
ATE124405T1 (de) 1,4,7,10-tetraazacyclododecan-butyltriole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel.
IL90435A (en) 4-(quinoline-2-yl-methoxy) phenylacetic acid derivatives, their preparation and pharmaceutical compositions containing them
ATE121295T1 (de) Augentropfenarzneimittel.
DE69400334T2 (de) Diaminsalze von clavulansäure
DE68909412D1 (de) Salze von glykosaminoglykanen, verfahren zu ihrer herstellung und diese salze enthaltende pharmazeutische zusammensetzungen.
TR28873A (tr) N-sübstitüe edilmis, N,N'-kaynasik heterosiklik benzoik asit üretmeye mahsus yöntem.
SE9300758L (sv) Förfarande för framställning av kavulansyrasalter
DE3767894D1 (de) 1,2-dithiol-3-thion-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellung.
ZA834409B (en) 1,4-dihydropyridine derivatives in optically active or in racemate form and their production and pharmaceutical compositions
DE59401990D1 (de) Imidazolyl-substituierte Phenylessigsäureprolinamide
DE3675378D1 (de) 16,17-acetalsubstituierte pregnan-21-saeure, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate.
NO920313D0 (no) Fremgangsmaate for fremstilling av rasemisk og optisk aktiv 1,2,3,4-tetrahydroisokinolin-3-karbonsyre samt forprodukter derav
WO1995022544A3 (de) Substituierte 1,3,8-triaza-spiro(4,5)-decan-4-on-derivate als vorstufen zur herstellung von pharmazeutika
ZA908298B (en) Optically active thiazetoquinoline-3-carboxylic acid compound,method for preparation thereof,and a pharmaceutical composition comprising the same
AU6629590A (en) N-(3',4'-dimethoxycinnamoyl)anthranilic acid
DE3675671D1 (de) Substituierte 1,8-naphthyridinone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE423151T1 (de) Salze von glykosaminoglykanen, verfahren zu ihrer herstellung und diese salze enthaltende pharmazeutische zusammensetzungen.
NO885289L (no) Herdbar sammensetning paa basis av et michael-addisjonsprodukt, fremgangsmaate for fremstilling samt anvendelse av den
ATE58530T1 (de) 1,4-dihydropyridinverbindungen und ihre herstellung und pharmazeutische formulierung.
DE3675747D1 (de) 1,4-dihydropyridinverbindungen und ihre herstellung und pharmazeutische formulierung.
FI941910A (fi) 2-amino-5-syaani-4-kinolyylidihydropyridiiniesterit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeissä