DE69400334T2 - Diaminsalze von clavulansäure - Google Patents

Diaminsalze von clavulansäure

Info

Publication number
DE69400334T2
DE69400334T2 DE69400334T DE69400334T DE69400334T2 DE 69400334 T2 DE69400334 T2 DE 69400334T2 DE 69400334 T DE69400334 T DE 69400334T DE 69400334 T DE69400334 T DE 69400334T DE 69400334 T2 DE69400334 T2 DE 69400334T2
Authority
DE
Germany
Prior art keywords
clavulanic acid
diamine salts
salts
diamine
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69400334T
Other languages
English (en)
Other versions
DE69400334D1 (de
Inventor
Pieter Weber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke DSM NV
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Publication of DE69400334D1 publication Critical patent/DE69400334D1/de
Application granted granted Critical
Publication of DE69400334T2 publication Critical patent/DE69400334T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DE69400334T 1993-03-26 1994-03-22 Diaminsalze von clavulansäure Expired - Fee Related DE69400334T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP93200872 1993-03-26
PCT/EP1994/000919 WO1994022873A1 (en) 1993-03-26 1994-03-22 Diamine salts of clavulanic acid
US08/457,985 US5719277A (en) 1993-03-26 1995-06-01 Diamine salts of clavulanic acid

Publications (2)

Publication Number Publication Date
DE69400334D1 DE69400334D1 (de) 1996-08-29
DE69400334T2 true DE69400334T2 (de) 1997-02-13

Family

ID=26133724

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69400334T Expired - Fee Related DE69400334T2 (de) 1993-03-26 1994-03-22 Diaminsalze von clavulansäure
DE0647229T Pending DE647229T1 (de) 1993-03-26 1994-03-22 Diaminsalze von clavulansäure.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE0647229T Pending DE647229T1 (de) 1993-03-26 1994-03-22 Diaminsalze von clavulansäure.

Country Status (22)

Country Link
US (1) US5719277A (de)
EP (2) EP0719778A1 (de)
CN (1) CN1041933C (de)
AT (1) ATE140703T1 (de)
AU (1) AU682030B2 (de)
CA (1) CA2135671A1 (de)
CY (1) CY1966A (de)
CZ (1) CZ284855B6 (de)
DE (2) DE69400334T2 (de)
DK (1) DK0647229T3 (de)
ES (1) ES2070109T3 (de)
FI (1) FI945510A (de)
HK (1) HK217196A (de)
HU (1) HUT69372A (de)
IL (1) IL109139A (de)
NO (1) NO301767B1 (de)
NZ (1) NZ263564A (de)
PL (1) PL306371A1 (de)
RO (1) RO112113B1 (de)
SK (1) SK279918B6 (de)
WO (1) WO1994022873A1 (de)
ZA (1) ZA942133B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT399155B (de) * 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
GB2282810B (en) * 1992-06-11 1997-02-26 Smithkline Beecham Plc Preparation or purification of clavulanic acid
SI9300296B (sl) * 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
AU678752B3 (en) * 1992-06-11 1997-06-05 Smithkline Beecham Plc Process for the preparation of clavulanic acid
SI9400107A (en) * 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts
DE69618045D1 (de) * 1995-02-25 2002-01-31 Spurcourt Ltd Clavulansäure Salz
SI9500134B (sl) 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
SI9500265A1 (en) * 1995-08-28 1997-02-28 Lek Tovarna Farmacevtskih Process for purification of the aqueous fermented broth filtrate of streptomyces sp. p 6621 ferm p 2804 by ultrafiltration
US6071532A (en) * 1996-10-15 2000-06-06 Emory University Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof
WO2000004028A1 (en) * 1998-07-16 2000-01-27 Dsm N.V. Improved process for the preparation of salts and esters of clavulanic acid
US6908663B1 (en) * 2000-11-15 2005-06-21 Awi Licensing Company Pigmented radiation cured wear layer
CN105384758B (zh) * 2015-12-01 2018-05-01 国药集团威奇达药业有限公司 克拉维酸胺盐的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE41109B1 (en) * 1974-04-20 1979-10-24 Beecham Group Ltd Novel -lactam antibiotic from streptomyces clavuligerus
DE3063683D1 (en) * 1979-08-24 1983-07-14 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
ES2010143A6 (es) * 1989-03-01 1989-10-16 Pharma Mar S A Pharmar Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp.
AT399155B (de) * 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) * 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
GB9305565D0 (en) * 1993-03-18 1993-05-05 Smithkline Beecham Plc Novel compounds and processes

Also Published As

Publication number Publication date
EP0647229B1 (de) 1996-07-24
NO944531D0 (no) 1994-11-25
EP0719778A1 (de) 1996-07-03
NO944531L (no) 1994-11-25
CN1041933C (zh) 1999-02-03
FI945510A0 (fi) 1994-11-23
DE647229T1 (de) 1996-01-18
AU682030B2 (en) 1997-09-18
AU6429494A (en) 1994-10-24
SK144294A3 (en) 1995-06-07
PL306371A1 (en) 1995-03-20
FI945510A (fi) 1994-11-23
HK217196A (en) 1996-12-27
HU9403383D0 (en) 1995-02-28
RO112113B1 (ro) 1997-05-30
DK0647229T3 (da) 1996-10-07
US5719277A (en) 1998-02-17
ATE140703T1 (de) 1996-08-15
ES2070109T3 (es) 1996-12-01
IL109139A (en) 1997-03-18
ES2070109T1 (es) 1995-06-01
NZ263564A (en) 1995-12-21
SK279918B6 (sk) 1999-05-07
NO301767B1 (no) 1997-12-08
ZA942133B (en) 1995-02-21
WO1994022873A1 (en) 1994-10-13
CN1108029A (zh) 1995-09-06
CZ284855B6 (cs) 1999-03-17
CY1966A (en) 1997-07-04
DE69400334D1 (de) 1996-08-29
CA2135671A1 (en) 1994-10-13
EP0647229A1 (de) 1995-04-12
HUT69372A (en) 1995-09-28
CZ286394A3 (en) 1995-03-15
IL109139A0 (en) 1994-06-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DSM N.V., HEERLEN, NL

8339 Ceased/non-payment of the annual fee