SK279767B6 - Farmaceutická kombinácia na použitie pri ošetrovan - Google Patents

Farmaceutická kombinácia na použitie pri ošetrovan Download PDF

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Publication number
SK279767B6
SK279767B6 SK951-93A SK95193A SK279767B6 SK 279767 B6 SK279767 B6 SK 279767B6 SK 95193 A SK95193 A SK 95193A SK 279767 B6 SK279767 B6 SK 279767B6
Authority
SK
Slovakia
Prior art keywords
formula
component
pharmaceutical
acid
compound
Prior art date
Application number
SK951-93A
Other languages
English (en)
Slovak (sk)
Other versions
SK95193A3 (en
Inventor
George R. Painter Iii
Phillip A. Furman
Original Assignee
The Wellcome Foundation Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Wellcome Foundation Limited filed Critical The Wellcome Foundation Limited
Publication of SK95193A3 publication Critical patent/SK95193A3/sk
Publication of SK279767B6 publication Critical patent/SK279767B6/sk

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SK951-93A 1991-03-06 1992-03-05 Farmaceutická kombinácia na použitie pri ošetrovan SK279767B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919104740A GB9104740D0 (en) 1991-03-06 1991-03-06 Antiviral nucleoside combination
PCT/GB1992/000389 WO1992015309A1 (fr) 1991-03-06 1992-03-05 Combinaison antivirale de nucleosides

Publications (2)

Publication Number Publication Date
SK95193A3 SK95193A3 (en) 1994-01-12
SK279767B6 true SK279767B6 (sk) 1999-03-12

Family

ID=10691101

Family Applications (1)

Application Number Title Priority Date Filing Date
SK951-93A SK279767B6 (sk) 1991-03-06 1992-03-05 Farmaceutická kombinácia na použitie pri ošetrovan

Country Status (26)

Country Link
US (2) US5234913A (fr)
EP (1) EP0574457B1 (fr)
JP (1) JP3442773B2 (fr)
KR (1) KR100225986B1 (fr)
AT (1) ATE185483T1 (fr)
AU (1) AU668860B2 (fr)
CA (1) CA2105487C (fr)
CZ (1) CZ283185B6 (fr)
DE (1) DE69230140T2 (fr)
DK (1) DK0574457T3 (fr)
ES (1) ES2138969T3 (fr)
GB (1) GB9104740D0 (fr)
GR (1) GR3032299T3 (fr)
HK (1) HK1004189A1 (fr)
HU (1) HU219492B (fr)
IE (1) IE920702A1 (fr)
IL (1) IL101145A (fr)
MY (1) MY108638A (fr)
NZ (1) NZ241842A (fr)
PT (1) PT100199B (fr)
RU (1) RU2110993C1 (fr)
SK (1) SK279767B6 (fr)
TW (1) TW199861B (fr)
UA (1) UA29429C2 (fr)
WO (1) WO1992015309A1 (fr)
ZA (1) ZA921660B (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6903224B2 (en) 1988-04-11 2005-06-07 Biochem Pharma Inc. Substituted 1,3-oxathiolanes
SE464168B (sv) * 1989-07-19 1991-03-18 Bo Fredrik Oeberg Antiviral komposition bestaaende av en 3'-fluoro-2',3'-dideoxynukleosidfoerening och en 2',3'-dideoxynukleosidfoerening (exempelvis azt)
US6703396B1 (en) 1990-02-01 2004-03-09 Emory University Method of resolution and antiviral activity of 1,3-oxathiolane nuclesoside enantiomers
US5276151A (en) * 1990-02-01 1994-01-04 Emory University Method of synthesis of 1,3-dioxolane nucleosides
US6642245B1 (en) * 1990-02-01 2003-11-04 Emory University Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane
US6069252A (en) * 1990-02-01 2000-05-30 Emory University Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers
US5204466A (en) * 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
US5444063A (en) * 1990-12-05 1995-08-22 Emory University Enantiomerically pure β-D-dioxolane nucleosides with selective anti-Hepatitis B virus activity
US5925643A (en) * 1990-12-05 1999-07-20 Emory University Enantiomerically pure β-D-dioxolane-nucleosides
GB9104740D0 (en) * 1991-03-06 1991-04-17 Wellcome Found Antiviral nucleoside combination
US6812233B1 (en) * 1991-03-06 2004-11-02 Emory University Therapeutic nucleosides
US5817667A (en) * 1991-04-17 1998-10-06 University Of Georgia Research Foudation Compounds and methods for the treatment of cancer
SK279262B6 (sk) * 1991-05-16 1998-08-05 Glaxo Group Limited Protivírusová zmes, farmaceutický prostriedok s je
GB9116601D0 (en) * 1991-08-01 1991-09-18 Iaf Biochem Int 1,3-oxathiolane nucleoside analogues
US6177435B1 (en) 1992-05-13 2001-01-23 Glaxo Wellcome Inc. Therapeutic combinations
US20020120130A1 (en) * 1993-09-10 2002-08-29 Gilles Gosselin 2' or 3' -deoxy and 2', 3' -dideoxy-beta-L-pentofuranonucleo-side compounds, method of preparation and application in therapy, especially as anti- viral agents
US5587362A (en) * 1994-01-28 1996-12-24 Univ. Of Ga Research Foundation L-nucleosides
WO1995024904A1 (fr) * 1994-03-16 1995-09-21 Tanox Biosystems, Inc. Inhibition synergique d'infections par vih-1 au moyen d'un inhibiteur de transcriptase inverse de nucleosides et d'anticorps anti vih-1
IL115156A (en) * 1994-09-06 2000-07-16 Univ Georgia Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines
US5703058A (en) * 1995-01-27 1997-12-30 Emory University Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent
US6391859B1 (en) 1995-01-27 2002-05-21 Emory University [5-Carboxamido or 5-fluoro]-[2′,3′-unsaturated or 3′-modified]-pyrimidine nucleosides
US5808040A (en) * 1995-01-30 1998-09-15 Yale University L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides
MY115461A (en) * 1995-03-30 2003-06-30 Wellcome Found Synergistic combinations of zidovudine, 1592u89 and 3tc
EP0831852B1 (fr) * 1995-06-07 2006-11-29 Emory University Nucleosides ayant une activite anti-virus de l'hepatite b
IL127350A0 (en) * 1996-06-25 1999-10-28 Glaxo Group Ltd Combinations comprising VX478 zidovudine and/or 1592U89 for use in the treatment of HIV
CN1228026A (zh) * 1996-06-25 1999-09-08 葛兰素集团有限公司 用于治疗hiv感染的含有vx478、叠氮胸苷、ftc和/或3tc的复方制剂
US5753789A (en) * 1996-07-26 1998-05-19 Yale University Oligonucleotides containing L-nucleosides
EA005097B1 (ru) * 1997-03-19 2004-10-28 Эмори Юниверсити Синтез 1,3-оксаселеноланнуклеозидов, обладающих активностью против вируса иммунодефицита человека и против вируса гепатита-b
WO1998044913A2 (fr) 1997-04-07 1998-10-15 Triangle Pharmaceuticals, Inc. Utilisation de mkc-442 en combinaison avec d'autres agents antiviraux
US6040434A (en) * 1997-12-01 2000-03-21 Inaba; Tadanobu Aldehyde oxidase inhibitors for treatment of aids
JP2002518452A (ja) * 1998-06-24 2002-06-25 エモリ ユニバーシティ Hivの治療薬物の製造のための他の抗hiv薬と組み合わせた3’−アジド−2’,3’−ジデオキシウリジンの使用
ES2537540T3 (es) 1998-08-12 2015-06-09 Gilead Sciences, Inc. Método de fabricación de nucleósidos de 1,3-dioxolano y 1,3-oxatiolano
US6979561B1 (en) 1998-10-09 2005-12-27 Gilead Sciences, Inc. Non-homogeneous systems for the resolution of enantiomeric mixtures
PT1382343E (pt) * 1998-11-02 2010-03-10 Gilead Sciences Inc Terapia de combinação para tratamento do vírus da hepatite b
US6436948B1 (en) 2000-03-03 2002-08-20 University Of Georgia Research Foundation Inc. Method for the treatment of psoriasis and genital warts
CN102911166B (zh) * 2001-03-01 2016-08-17 基利得科学公司 顺-ftc的多晶型物及其它晶型
UA93354C2 (ru) * 2004-07-09 2011-02-10 Гилиад Сайенсиз, Инк. Местный противовирусный препарат

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MC1742A1 (fr) * 1985-03-16 1987-02-26 Wellcome Found Procede pour preparer un derive de 3'-azido-3'desoxythymigline et procede pour preparer une formulation pharmaceutique le contenant
US4874751A (en) * 1985-03-16 1989-10-17 Burroughs Wellcome Co. Antibacterial treatment
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
GR861255B (en) * 1985-05-15 1986-09-16 Wellcome Found Therapeutic nucleosides
ZA878877B (en) * 1986-11-29 1988-05-24 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Treatment of diseases caused by viruses
US5159067A (en) * 1987-01-28 1992-10-27 University Of Georgia Research Foundation Inc. 5'-Diphosphohexose nucleoside pharmaceutical compositions
US4837311A (en) * 1987-06-22 1989-06-06 Hoffman-La Roche Inc. Anti-retroviral compounds
NZ228645A (en) * 1988-04-11 1991-09-25 Iaf Biochem Int 1,3-dioxolane derivatives substituted in the 5th position by a purine or pyrimidine radical; treatment of viral infections
US5041449A (en) * 1988-04-11 1991-08-20 Iaf Biochem International, Inc. 4-(nucleoside base)-substituted-1,3-dioxolanes useful for treatment of retroviral infections
US5047407A (en) * 1989-02-08 1991-09-10 Iaf Biochem International, Inc. 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
CA2055433A1 (fr) * 1989-05-15 1990-11-16 Jay H. Hoofnagle Methode de traitement de l'hepatite
US5071983A (en) * 1989-10-06 1991-12-10 Burroughs Wellcome Co. Therapeutic nucleosides
US5204466A (en) * 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
IT1249019B (it) * 1990-06-28 1995-02-11 Lamberti S P A L Emulsione acquosa di resine filmogene per la finitura di pelli, cuoio e croste di pelle e relativo procedimento di applicazione
EP0560794B1 (fr) * 1990-11-13 1996-09-18 Biochem Pharma Inc 1,3-oxathiolanes substitues ayant des proprietes antivirales
IL100502A (en) * 1991-01-03 1995-12-08 Iaf Biochem Int PHARMACEUTICAL PREPARATIONS CONTAINING CIS-4-AMINO-1-) 2-HYDROXIMETHIL-1,3-OXETYOLEN-5-IL (-
GB9104740D0 (en) * 1991-03-06 1991-04-17 Wellcome Found Antiviral nucleoside combination
SK279262B6 (sk) * 1991-05-16 1998-08-05 Glaxo Group Limited Protivírusová zmes, farmaceutický prostriedok s je

Also Published As

Publication number Publication date
HU219492B (hu) 2001-04-28
TW199861B (fr) 1993-02-11
CA2105487C (fr) 2002-09-24
JP3442773B2 (ja) 2003-09-02
GB9104740D0 (en) 1991-04-17
PT100199B (pt) 1999-06-30
EP0574457B1 (fr) 1999-10-13
UA29429C2 (uk) 2000-11-15
CZ183693A3 (en) 1994-06-15
CZ283185B6 (cs) 1998-01-14
ES2138969T3 (es) 2000-02-01
AU668860B2 (en) 1996-05-23
HK1004189A1 (en) 1998-11-20
DE69230140T2 (de) 2000-04-06
IE920702A1 (en) 1992-09-09
DE69230140D1 (de) 1999-11-18
IL101145A (en) 1996-08-04
US5234913A (en) 1993-08-10
KR100225986B1 (ko) 1999-10-15
SK95193A3 (en) 1994-01-12
WO1992015309A1 (fr) 1992-09-17
EP0574457A1 (fr) 1993-12-22
GR3032299T3 (en) 2000-04-27
CA2105487A1 (fr) 1992-09-07
IL101145A0 (en) 1992-11-15
HUT72460A (en) 1996-04-29
MY108638A (en) 1996-10-31
US6107288A (en) 2000-08-22
DK0574457T3 (da) 2000-04-17
HU9302496D0 (en) 1993-11-29
NZ241842A (en) 1994-08-26
JPH06506199A (ja) 1994-07-14
RU2110993C1 (ru) 1998-05-20
ZA921660B (en) 1993-09-06
ATE185483T1 (de) 1999-10-15
PT100199A (pt) 1993-07-30
AU1351292A (en) 1992-10-06

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MK4A Patent expired

Expiry date: 20120305