SK279039B6 - Spôsob prípravy derivátov ergolínu - Google Patents

Spôsob prípravy derivátov ergolínu Download PDF

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Publication number
SK279039B6
SK279039B6 SK1401-93A SK140193A SK279039B6 SK 279039 B6 SK279039 B6 SK 279039B6 SK 140193 A SK140193 A SK 140193A SK 279039 B6 SK279039 B6 SK 279039B6
Authority
SK
Slovakia
Prior art keywords
group
reacted
formula
reactants
process according
Prior art date
Application number
SK1401-93A
Other languages
English (en)
Slovak (sk)
Other versions
SK140193A3 (en
Inventor
Ilaria Candiani
Walter Cabri
Angelo Bedeschi
Franco Zarini
Original Assignee
Farmitalia Carlo Erba S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba S.R.L. filed Critical Farmitalia Carlo Erba S.R.L.
Publication of SK140193A3 publication Critical patent/SK140193A3/sk
Publication of SK279039B6 publication Critical patent/SK279039B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
SK1401-93A 1992-03-12 1993-02-15 Spôsob prípravy derivátov ergolínu SK279039B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929205439A GB9205439D0 (en) 1992-03-12 1992-03-12 Process for the synthesis of ergoline derivatives
PCT/EP1993/000360 WO1993018034A1 (en) 1992-03-12 1993-02-15 Process for the preparation of ergoline derivatives

Publications (2)

Publication Number Publication Date
SK140193A3 SK140193A3 (en) 1994-11-09
SK279039B6 true SK279039B6 (sk) 1998-05-06

Family

ID=10712024

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1401-93A SK279039B6 (sk) 1992-03-12 1993-02-15 Spôsob prípravy derivátov ergolínu

Country Status (25)

Country Link
US (1) US5382669A (zh)
EP (1) EP0593692B1 (zh)
JP (1) JP3339858B2 (zh)
KR (1) KR100274102B1 (zh)
CN (1) CN1038510C (zh)
AT (1) ATE180783T1 (zh)
AU (1) AU653099B2 (zh)
CA (1) CA2106371C (zh)
CZ (1) CZ281708B6 (zh)
DE (1) DE69325138D1 (zh)
FI (1) FI113473B (zh)
GB (1) GB9205439D0 (zh)
HU (1) HU210407B (zh)
IL (1) IL104973A (zh)
MX (1) MX9301297A (zh)
MY (1) MY109152A (zh)
NO (1) NO302754B1 (zh)
NZ (1) NZ249115A (zh)
PH (1) PH30138A (zh)
RU (1) RU2118323C1 (zh)
SK (1) SK279039B6 (zh)
TW (1) TW215089B (zh)
UA (1) UA26400C2 (zh)
WO (1) WO1993018034A1 (zh)
ZA (1) ZA931720B (zh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0007308D0 (en) 2000-03-24 2000-05-17 Pharmacia & Upjohn Spa Process for preparing crystalline form | of cabergoline
US6696568B2 (en) 2001-04-16 2004-02-24 Finetech Ltd. Process and intermediates for production of cabergoline and related compounds
IL155545A (en) * 2003-04-21 2009-12-24 Finetech Pharmaceutical Ltd Solvate form of cabergoline
HUP0400517A3 (en) * 2004-03-04 2006-05-29 Richter Gedeon Vegyeszet Process for producing cabergoline
GB0409785D0 (en) * 2004-04-30 2004-06-09 Resolution Chemicals Ltd Preparation of cabergoline
FR2877945A1 (fr) * 2004-11-18 2006-05-19 Archemis Sa Procede de la preparation de la cabergoline
EP1858894A1 (en) 2005-03-17 2007-11-28 Synthon Argentina S.A. Improved process for making cabergoline
GB0505965D0 (en) * 2005-03-23 2005-04-27 Resolution Chemicals Ltd Preparation of cabergoline
EP1925616A1 (en) * 2006-10-26 2008-05-28 LEK Pharmaceuticals D.D. Process for the preparation of crystal forms of cabergoline via stable solvates of cabergoline
US7939665B2 (en) * 2007-05-04 2011-05-10 Apotex Pharmachem Inc. Efficient process for the preparation of cabergoline and its intermediates
WO2014078857A1 (en) 2012-11-19 2014-05-22 Regents Of The University Of Minnesota Ergoline derivatives as dopamine receptor modulators

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2103603B (en) * 1981-08-11 1985-04-11 Erba Farmitalia Ergoline derivatives

Also Published As

Publication number Publication date
MY109152A (en) 1996-12-31
EP0593692A1 (en) 1994-04-27
UA26400C2 (uk) 1999-08-30
ZA931720B (en) 1993-11-01
PH30138A (en) 1997-01-21
MX9301297A (es) 1993-09-01
TW215089B (zh) 1993-10-21
NZ249115A (en) 1995-04-27
CN1038510C (zh) 1998-05-27
GB9205439D0 (en) 1992-04-22
US5382669A (en) 1995-01-17
SK140193A3 (en) 1994-11-09
JP3339858B2 (ja) 2002-10-28
ATE180783T1 (de) 1999-06-15
CZ281708B6 (cs) 1996-12-11
AU3497493A (en) 1993-10-05
IL104973A (en) 1997-06-10
NO934077L (no) 1993-11-11
CA2106371A1 (en) 1993-09-13
FI934933A0 (fi) 1993-11-08
DE69325138D1 (de) 1999-07-08
FI934933A (fi) 1993-11-08
WO1993018034A1 (en) 1993-09-16
IL104973A0 (en) 1993-07-08
HU210407B (en) 1995-04-28
FI113473B (fi) 2004-04-30
EP0593692B1 (en) 1999-06-02
AU653099B2 (en) 1994-09-15
CA2106371C (en) 2003-09-23
HUT66712A (en) 1994-12-28
CZ271593A3 (en) 1994-04-13
CN1076196A (zh) 1993-09-15
JPH06507648A (ja) 1994-09-01
RU2118323C1 (ru) 1998-08-27
NO934077D0 (no) 1993-11-11
KR100274102B1 (ko) 2000-12-15
NO302754B1 (no) 1998-04-20

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