DE69325138D1 - Verfahren zur herstellung von ergolin derivaten - Google Patents
Verfahren zur herstellung von ergolin derivatenInfo
- Publication number
- DE69325138D1 DE69325138D1 DE69325138T DE69325138T DE69325138D1 DE 69325138 D1 DE69325138 D1 DE 69325138D1 DE 69325138 T DE69325138 T DE 69325138T DE 69325138 T DE69325138 T DE 69325138T DE 69325138 D1 DE69325138 D1 DE 69325138D1
- Authority
- DE
- Germany
- Prior art keywords
- formula
- producing
- derivatives
- image
- ergolin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929205439A GB9205439D0 (en) | 1992-03-12 | 1992-03-12 | Process for the synthesis of ergoline derivatives |
PCT/EP1993/000360 WO1993018034A1 (en) | 1992-03-12 | 1993-02-15 | Process for the preparation of ergoline derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69325138D1 true DE69325138D1 (de) | 1999-07-08 |
Family
ID=10712024
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69325138T Expired - Lifetime DE69325138D1 (de) | 1992-03-12 | 1993-02-15 | Verfahren zur herstellung von ergolin derivaten |
Country Status (25)
Country | Link |
---|---|
US (1) | US5382669A (de) |
EP (1) | EP0593692B1 (de) |
JP (1) | JP3339858B2 (de) |
KR (1) | KR100274102B1 (de) |
CN (1) | CN1038510C (de) |
AT (1) | ATE180783T1 (de) |
AU (1) | AU653099B2 (de) |
CA (1) | CA2106371C (de) |
CZ (1) | CZ281708B6 (de) |
DE (1) | DE69325138D1 (de) |
FI (1) | FI113473B (de) |
GB (1) | GB9205439D0 (de) |
HU (1) | HU210407B (de) |
IL (1) | IL104973A (de) |
MX (1) | MX9301297A (de) |
MY (1) | MY109152A (de) |
NO (1) | NO302754B1 (de) |
NZ (1) | NZ249115A (de) |
PH (1) | PH30138A (de) |
RU (1) | RU2118323C1 (de) |
SK (1) | SK279039B6 (de) |
TW (1) | TW215089B (de) |
UA (1) | UA26400C2 (de) |
WO (1) | WO1993018034A1 (de) |
ZA (1) | ZA931720B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0007308D0 (en) | 2000-03-24 | 2000-05-17 | Pharmacia & Upjohn Spa | Process for preparing crystalline form | of cabergoline |
US6696568B2 (en) | 2001-04-16 | 2004-02-24 | Finetech Ltd. | Process and intermediates for production of cabergoline and related compounds |
IL155545A (en) * | 2003-04-21 | 2009-12-24 | Finetech Pharmaceutical Ltd | Solvate form of cabergoline |
HUP0400517A3 (en) * | 2004-03-04 | 2006-05-29 | Richter Gedeon Vegyeszet | Process for producing cabergoline |
GB0409785D0 (en) * | 2004-04-30 | 2004-06-09 | Resolution Chemicals Ltd | Preparation of cabergoline |
FR2877945A1 (fr) * | 2004-11-18 | 2006-05-19 | Archemis Sa | Procede de la preparation de la cabergoline |
WO2006097345A1 (en) | 2005-03-17 | 2006-09-21 | Synthon Argentina S.A. | Improved process for making cabergoline |
GB0505965D0 (en) * | 2005-03-23 | 2005-04-27 | Resolution Chemicals Ltd | Preparation of cabergoline |
EP1925616A1 (de) * | 2006-10-26 | 2008-05-28 | LEK Pharmaceuticals D.D. | Verfahren zur Herstellung kristalliner Formen des Cabergolins via stabile Solvate des Cabergolins |
US7939665B2 (en) * | 2007-05-04 | 2011-05-10 | Apotex Pharmachem Inc. | Efficient process for the preparation of cabergoline and its intermediates |
US9670199B2 (en) | 2012-11-19 | 2017-06-06 | Regents Of The University Of Minnesota | Ergoline derivatives as dopamine receptor modulators |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2103603B (en) * | 1981-08-11 | 1985-04-11 | Erba Farmitalia | Ergoline derivatives |
-
1992
- 1992-03-12 GB GB929205439A patent/GB9205439D0/en active Pending
-
1993
- 1993-02-15 DE DE69325138T patent/DE69325138D1/de not_active Expired - Lifetime
- 1993-02-15 UA UA93003963A patent/UA26400C2/uk unknown
- 1993-02-15 CA CA002106371A patent/CA2106371C/en not_active Expired - Fee Related
- 1993-02-15 NZ NZ249115A patent/NZ249115A/en not_active IP Right Cessation
- 1993-02-15 RU RU93058546A patent/RU2118323C1/ru not_active IP Right Cessation
- 1993-02-15 AT AT93903972T patent/ATE180783T1/de active
- 1993-02-15 KR KR1019930703386A patent/KR100274102B1/ko not_active IP Right Cessation
- 1993-02-15 EP EP93903972A patent/EP0593692B1/de not_active Expired - Lifetime
- 1993-02-15 JP JP51527993A patent/JP3339858B2/ja not_active Expired - Fee Related
- 1993-02-15 CZ CZ932715A patent/CZ281708B6/cs not_active IP Right Cessation
- 1993-02-15 WO PCT/EP1993/000360 patent/WO1993018034A1/en active IP Right Grant
- 1993-02-15 AU AU34974/93A patent/AU653099B2/en not_active Ceased
- 1993-02-15 HU HU9303541A patent/HU210407B/hu unknown
- 1993-02-15 SK SK1401-93A patent/SK279039B6/sk unknown
- 1993-02-16 TW TW082101067A patent/TW215089B/zh active
- 1993-03-08 IL IL104973A patent/IL104973A/xx not_active IP Right Cessation
- 1993-03-09 US US08/028,286 patent/US5382669A/en not_active Expired - Lifetime
- 1993-03-09 PH PH45839A patent/PH30138A/en unknown
- 1993-03-09 CN CN93102663A patent/CN1038510C/zh not_active Expired - Fee Related
- 1993-03-09 MX MX9301297A patent/MX9301297A/es not_active IP Right Cessation
- 1993-03-10 ZA ZA931720A patent/ZA931720B/xx unknown
- 1993-03-11 MY MYPI93000439A patent/MY109152A/en unknown
- 1993-11-08 FI FI934933A patent/FI113473B/fi active
- 1993-11-11 NO NO934077A patent/NO302754B1/no unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de | ||
8328 | Change in the person/name/address of the agent |
Free format text: HOFFMANN * EITLE, 81925 MUENCHEN |