SK278528B6 - 5-(2-methyl-4,4,4-trifluorobutylcarbamoyl)indole derivatives, preparation method thereof and pharmaceutical compositions containing them - Google Patents
5-(2-methyl-4,4,4-trifluorobutylcarbamoyl)indole derivatives, preparation method thereof and pharmaceutical compositions containing them Download PDFInfo
- Publication number
- SK278528B6 SK278528B6 SK6146-90A SK614690A SK278528B6 SK 278528 B6 SK278528 B6 SK 278528B6 SK 614690 A SK614690 A SK 614690A SK 278528 B6 SK278528 B6 SK 278528B6
- Authority
- SK
- Slovakia
- Prior art keywords
- methyl
- formula
- acid
- compound
- ylmethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/15—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898927981A GB8927981D0 (en) | 1989-12-11 | 1989-12-11 | Carbamoyl derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
SK614690A3 SK614690A3 (en) | 1997-08-06 |
SK278528B6 true SK278528B6 (en) | 1997-08-06 |
Family
ID=10667774
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK6146-90A SK278528B6 (en) | 1989-12-11 | 1990-12-10 | 5-(2-methyl-4,4,4-trifluorobutylcarbamoyl)indole derivatives, preparation method thereof and pharmaceutical compositions containing them |
Country Status (32)
Country | Link |
---|---|
EP (1) | EP0432984B1 (no) |
JP (1) | JPH0822849B2 (no) |
KR (1) | KR100192999B1 (no) |
CN (1) | CN1025786C (no) |
AP (1) | AP192A (no) |
AT (1) | ATE163641T1 (no) |
AU (1) | AU642182B2 (no) |
BG (2) | BG50606A3 (no) |
CA (1) | CA2031897C (no) |
CZ (1) | CZ614690A3 (no) |
DE (1) | DE69032083T2 (no) |
DK (1) | DK0432984T3 (no) |
ES (1) | ES2112832T3 (no) |
FI (1) | FI95029C (no) |
GB (2) | GB8927981D0 (no) |
GR (1) | GR3026279T3 (no) |
HK (1) | HK1003830A1 (no) |
HR (1) | HRP930326B1 (no) |
HU (2) | HU210441B (no) |
IE (1) | IE904448A1 (no) |
IL (1) | IL96621A (no) |
MY (1) | MY106363A (no) |
NO (1) | NO174198C (no) |
PL (2) | PL167449B1 (no) |
PT (1) | PT96154B (no) |
RO (1) | RO108562B1 (no) |
RU (1) | RU2002740C1 (no) |
SI (1) | SI9012330A (no) |
SK (1) | SK278528B6 (no) |
TW (1) | TW219329B (no) |
YU (1) | YU48218B (no) |
ZA (1) | ZA909898B (no) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE113581T1 (de) * | 1990-05-04 | 1994-11-15 | Ciba Geigy Ag | Substituierte indole. |
GB9020338D0 (en) * | 1990-09-18 | 1990-10-31 | Lilly Industries Ltd | Pharmaceutical compounds |
GB9026427D0 (en) * | 1990-12-05 | 1991-01-23 | Ici Plc | Chemical process |
GB9026425D0 (en) * | 1990-12-05 | 1991-01-23 | Ici Plc | Process |
GB9119001D0 (en) * | 1991-09-05 | 1991-10-23 | Ici Plc | Pharmaceutical agents |
GR1001368B (el) * | 1992-10-08 | 1993-10-29 | Ici Plc | Φαρμακευτικοί φορείς. |
ES2050611B1 (es) * | 1992-10-08 | 1994-12-16 | Ici Plc | Una nueva forma fisica de un derivado de carbamoilindol con propiedades antagonistas de leucotrienos. |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4524152A (en) * | 1982-12-30 | 1985-06-18 | Pennwalt Corporation | 1-Cyano-3-(fluoroalkyl)guanidines for lowering blood pressure |
EP0227241B1 (en) * | 1985-10-17 | 1996-09-11 | Zeneca Inc. | Medicinal indole and indazole keto sulphone derivatives |
GB8623429D0 (en) * | 1985-10-17 | 1986-11-05 | Ici America Inc | Carboximide derivatives |
MY103259A (en) * | 1987-04-15 | 1993-05-29 | Ici America Inc | Aliphatic carboxamides |
GB8906032D0 (en) * | 1988-04-14 | 1989-04-26 | Ici America Inc | Hetera-aliphatic carboxamides |
GB9026425D0 (en) * | 1990-12-05 | 1991-01-23 | Ici Plc | Process |
-
1989
- 1989-12-11 GB GB898927981A patent/GB8927981D0/en active Pending
-
1990
- 1990-12-10 EP EP90313373A patent/EP0432984B1/en not_active Expired - Lifetime
- 1990-12-10 SK SK6146-90A patent/SK278528B6/sk unknown
- 1990-12-10 IL IL9662190A patent/IL96621A/en not_active IP Right Cessation
- 1990-12-10 RU SU04831920A patent/RU2002740C1/ru not_active IP Right Cessation
- 1990-12-10 PL PL90304868A patent/PL167449B1/pl unknown
- 1990-12-10 NO NO905327A patent/NO174198C/no unknown
- 1990-12-10 BG BG95502/91A patent/BG50606A3/xx unknown
- 1990-12-10 ZA ZA909898A patent/ZA909898B/xx unknown
- 1990-12-10 MY MYPI90002157A patent/MY106363A/en unknown
- 1990-12-10 YU YU233090A patent/YU48218B/sh unknown
- 1990-12-10 GB GB9026797A patent/GB2238790B/en not_active Revoked
- 1990-12-10 CZ CS906146A patent/CZ614690A3/cs not_active IP Right Cessation
- 1990-12-10 SI SI9012330A patent/SI9012330A/sl unknown
- 1990-12-10 HU HU908137A patent/HU210441B/hu not_active IP Right Cessation
- 1990-12-10 DK DK90313373T patent/DK0432984T3/da active
- 1990-12-10 AP APAP/P/1990/000230A patent/AP192A/en active
- 1990-12-10 AT AT90313373T patent/ATE163641T1/de not_active IP Right Cessation
- 1990-12-10 BG BG93426A patent/BG60015A3/xx unknown
- 1990-12-10 ES ES90313373T patent/ES2112832T3/es not_active Expired - Lifetime
- 1990-12-10 PL PL90288184A patent/PL166516B1/pl unknown
- 1990-12-10 AU AU67917/90A patent/AU642182B2/en not_active Ceased
- 1990-12-10 RO RO146517A patent/RO108562B1/ro unknown
- 1990-12-10 IE IE444890A patent/IE904448A1/en not_active IP Right Cessation
- 1990-12-10 DE DE69032083T patent/DE69032083T2/de not_active Expired - Lifetime
- 1990-12-10 CA CA002031897A patent/CA2031897C/en not_active Expired - Fee Related
- 1990-12-11 FI FI906084A patent/FI95029C/fi not_active IP Right Cessation
- 1990-12-11 CN CN90110406A patent/CN1025786C/zh not_active Expired - Lifetime
- 1990-12-11 JP JP2419290A patent/JPH0822849B2/ja not_active Expired - Lifetime
- 1990-12-11 PT PT96154A patent/PT96154B/pt not_active IP Right Cessation
- 1990-12-11 KR KR1019900020547A patent/KR100192999B1/ko not_active IP Right Cessation
- 1990-12-20 TW TW079110705A patent/TW219329B/zh not_active IP Right Cessation
-
1993
- 1993-03-11 HR HRP-2330/90A patent/HRP930326B1/xx not_active IP Right Cessation
-
1995
- 1995-06-12 HU HU95P/P00183P patent/HU210877A9/hu unknown
-
1998
- 1998-03-05 GR GR980400270T patent/GR3026279T3/el unknown
- 1998-04-02 HK HK98102807A patent/HK1003830A1/xx not_active IP Right Cessation
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