SK121797A3 - Radiographic contrasting agent for computerised tomography and urography - Google Patents
Radiographic contrasting agent for computerised tomography and urography Download PDFInfo
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- SK121797A3 SK121797A3 SK1217-97A SK121797A SK121797A3 SK 121797 A3 SK121797 A3 SK 121797A3 SK 121797 A SK121797 A SK 121797A SK 121797 A3 SK121797 A3 SK 121797A3
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- 238000007487 urography Methods 0.000 title claims description 9
- 238000003325 tomography Methods 0.000 title description 2
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- 230000002496 gastric effect Effects 0.000 description 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 description 1
- 239000012433 hydrogen halide Substances 0.000 description 1
- 229910000039 hydrogen halide Inorganic materials 0.000 description 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 150000007529 inorganic bases Chemical class 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 229960001025 iohexol Drugs 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- JMMWKPVZQRWMSS-UHFFFAOYSA-N isopropanol acetate Natural products CC(C)OC(C)=O JMMWKPVZQRWMSS-UHFFFAOYSA-N 0.000 description 1
- 229940011051 isopropyl acetate Drugs 0.000 description 1
- GWYFCOCPABKNJV-UHFFFAOYSA-N isovaleric acid Chemical compound CC(C)CC(O)=O GWYFCOCPABKNJV-UHFFFAOYSA-N 0.000 description 1
- 231100000636 lethal dose Toxicity 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 230000001926 lymphatic effect Effects 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 description 1
- 239000000347 magnesium hydroxide Substances 0.000 description 1
- 229910001862 magnesium hydroxide Inorganic materials 0.000 description 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- HFWWEMPLBCKNNM-UHFFFAOYSA-N n-[bis(hydroxyamino)methyl]hydroxylamine Chemical compound ONC(NO)NO HFWWEMPLBCKNNM-UHFFFAOYSA-N 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000012074 organic phase Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000009054 pathological process Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 239000003880 polar aprotic solvent Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 150000003512 tertiary amines Chemical class 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229960000103 thrombolytic agent Drugs 0.000 description 1
- 230000002537 thrombolytic effect Effects 0.000 description 1
- 230000007675 toxicity by organ Effects 0.000 description 1
- 231100000155 toxicity by organ Toxicity 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 125000005270 trialkylamine group Chemical group 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 210000001635 urinary tract Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19510864A DE19510864A1 (de) | 1995-03-16 | 1995-03-16 | Röntgenkontrastmittel für die Computertomographie und Urographie |
| PCT/EP1996/000735 WO1996028415A1 (de) | 1995-03-16 | 1996-02-21 | Röntgenkontrastmittel für die computertomographie und urographie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK121797A3 true SK121797A3 (en) | 1998-05-06 |
Family
ID=7757670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1217-97A SK121797A3 (en) | 1995-03-16 | 1996-02-21 | Radiographic contrasting agent for computerised tomography and urography |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0815072B1 (el) |
| JP (1) | JPH11501638A (el) |
| KR (1) | KR19980703059A (el) |
| AT (1) | ATE194138T1 (el) |
| AU (1) | AU4718696A (el) |
| CA (1) | CA2215385A1 (el) |
| CZ (1) | CZ291597A3 (el) |
| DE (2) | DE19510864A1 (el) |
| DK (1) | DK0815072T3 (el) |
| ES (1) | ES2148731T3 (el) |
| FI (1) | FI973692A (el) |
| GR (1) | GR3034472T3 (el) |
| HU (1) | HUP9800850A3 (el) |
| IL (1) | IL117373A0 (el) |
| NO (1) | NO974259L (el) |
| PL (1) | PL322200A1 (el) |
| PT (1) | PT815072E (el) |
| SK (1) | SK121797A3 (el) |
| WO (1) | WO1996028415A1 (el) |
| ZA (1) | ZA962142B (el) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19731591C2 (de) * | 1997-07-17 | 1999-09-16 | Schering Ag | Pharmazeutische Mittel enthaltend perfluoralkylgruppenhaltige Trijodaromaten und ihre Verwendung in der Tumortherapie und interventionellen Radiologie |
| DE19740403C2 (de) * | 1997-09-09 | 1999-11-11 | Schering Ag | Neue Kontrastmittel |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1548594A (en) * | 1976-06-11 | 1979-07-18 | Nyegaard & Co As | Triiodoisophthalic acid amides |
| DE2909439A1 (de) * | 1979-03-08 | 1980-09-18 | Schering Ag | Neue nichtionische roentgenkontrastmittel |
| IT1193211B (it) * | 1979-08-09 | 1988-06-15 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono |
| DE3937118A1 (de) * | 1989-11-03 | 1991-05-08 | Schering Ag | Nichtionische roentgenkontrastmittel mit hohem jodgehalt |
| US5075502A (en) * | 1989-12-13 | 1991-12-24 | Mallinckrodt, Inc. | Nonionic x-ray contrast agents, compositions and methods |
| WO1993010078A1 (es) * | 1991-11-18 | 1993-05-27 | Centro Investigacion Justesa Imagen S.A. | Nuevos agentes yodados no ionicos de contraste a los rayos x, metodo para su preparacion y composiciones galenicas que los contienen |
| EP0619744A4 (en) * | 1991-12-03 | 1995-02-08 | Mallinckrodt Medical Inc | NON-IONIC RADIOGRAPHIC CONTRAST METHODS, COMPOSITIONS AND AGENTS. |
| AU5093993A (en) * | 1992-09-02 | 1994-03-29 | Mallinckrodt Medical, Inc. | Nonionic X-ray contrast agents compositions and methods |
-
1995
- 1995-03-16 DE DE19510864A patent/DE19510864A1/de not_active Withdrawn
-
1996
- 1996-02-21 DK DK96902993T patent/DK0815072T3/da active
- 1996-02-21 KR KR1019970706468A patent/KR19980703059A/ko not_active Application Discontinuation
- 1996-02-21 DE DE59605508T patent/DE59605508D1/de not_active Expired - Lifetime
- 1996-02-21 PL PL96322200A patent/PL322200A1/xx unknown
- 1996-02-21 ES ES96902993T patent/ES2148731T3/es not_active Expired - Lifetime
- 1996-02-21 EP EP96902993A patent/EP0815072B1/de not_active Expired - Lifetime
- 1996-02-21 AU AU47186/96A patent/AU4718696A/en not_active Abandoned
- 1996-02-21 WO PCT/EP1996/000735 patent/WO1996028415A1/de not_active Application Discontinuation
- 1996-02-21 SK SK1217-97A patent/SK121797A3/sk unknown
- 1996-02-21 AT AT96902993T patent/ATE194138T1/de not_active IP Right Cessation
- 1996-02-21 PT PT96902993T patent/PT815072E/pt unknown
- 1996-02-21 CZ CZ972915A patent/CZ291597A3/cs unknown
- 1996-02-21 HU HU9800850A patent/HUP9800850A3/hu unknown
- 1996-02-21 CA CA002215385A patent/CA2215385A1/en not_active Abandoned
- 1996-02-21 JP JP8527203A patent/JPH11501638A/ja active Pending
- 1996-03-05 IL IL11737396A patent/IL117373A0/xx unknown
- 1996-03-15 ZA ZA962142A patent/ZA962142B/xx unknown
-
1997
- 1997-09-15 FI FI973692A patent/FI973692A/fi unknown
- 1997-09-15 NO NO974259A patent/NO974259L/no unknown
-
2000
- 2000-09-21 GR GR20000402161T patent/GR3034472T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE194138T1 (de) | 2000-07-15 |
| KR19980703059A (ko) | 1998-09-05 |
| JPH11501638A (ja) | 1999-02-09 |
| DE19510864A1 (de) | 1996-09-19 |
| GR3034472T3 (en) | 2000-12-29 |
| HUP9800850A2 (hu) | 1998-07-28 |
| DE59605508D1 (de) | 2000-08-03 |
| CA2215385A1 (en) | 1996-09-19 |
| IL117373A0 (en) | 1996-07-23 |
| EP0815072B1 (de) | 2000-06-28 |
| FI973692A0 (fi) | 1997-09-15 |
| AU4718696A (en) | 1996-10-02 |
| ES2148731T3 (es) | 2000-10-16 |
| NO974259L (no) | 1997-11-14 |
| EP0815072A1 (de) | 1998-01-07 |
| DK0815072T3 (da) | 2000-09-04 |
| FI973692A (fi) | 1997-09-15 |
| PT815072E (pt) | 2000-10-31 |
| MX9706555A (es) | 1997-11-29 |
| CZ291597A3 (cs) | 1998-02-18 |
| PL322200A1 (en) | 1998-01-19 |
| HUP9800850A3 (en) | 1998-08-28 |
| ZA962142B (en) | 1996-09-26 |
| NO974259D0 (no) | 1997-09-15 |
| WO1996028415A1 (de) | 1996-09-19 |
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