IL117373A0 - Triiodized isophthalic acid amides processes for the preparation thereof and pharmaceutical and diagnostic compositions containing the same - Google Patents

Triiodized isophthalic acid amides processes for the preparation thereof and pharmaceutical and diagnostic compositions containing the same

Info

Publication number
IL117373A0
IL117373A0 IL11737396A IL11737396A IL117373A0 IL 117373 A0 IL117373 A0 IL 117373A0 IL 11737396 A IL11737396 A IL 11737396A IL 11737396 A IL11737396 A IL 11737396A IL 117373 A0 IL117373 A0 IL 117373A0
Authority
IL
Israel
Prior art keywords
same
isophthalic acid
triiodized
pharmaceutical
processes
Prior art date
Application number
IL11737396A
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL117373A0 publication Critical patent/IL117373A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations

Abstract

A radiographic contrasting agent having the formula (I) based on triiodinated isophthalic acid amide is disclosed, as well as its use and a process for preparing the same. In the formula, R<1> stands for the methyl residue and R<2> for the 2,3-dihydroxypropyl residue or R<1> and R<2> stand each for a 2-hydroxyethyl residue.
IL11737396A 1995-03-16 1996-03-05 Triiodized isophthalic acid amides processes for the preparation thereof and pharmaceutical and diagnostic compositions containing the same IL117373A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19510864A DE19510864A1 (en) 1995-03-16 1995-03-16 X-ray contrast media for computed tomography and urography

Publications (1)

Publication Number Publication Date
IL117373A0 true IL117373A0 (en) 1996-07-23

Family

ID=7757670

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11737396A IL117373A0 (en) 1995-03-16 1996-03-05 Triiodized isophthalic acid amides processes for the preparation thereof and pharmaceutical and diagnostic compositions containing the same

Country Status (20)

Country Link
EP (1) EP0815072B1 (en)
JP (1) JPH11501638A (en)
KR (1) KR19980703059A (en)
AT (1) ATE194138T1 (en)
AU (1) AU4718696A (en)
CA (1) CA2215385A1 (en)
CZ (1) CZ291597A3 (en)
DE (2) DE19510864A1 (en)
DK (1) DK0815072T3 (en)
ES (1) ES2148731T3 (en)
FI (1) FI973692A0 (en)
GR (1) GR3034472T3 (en)
HU (1) HUP9800850A3 (en)
IL (1) IL117373A0 (en)
NO (1) NO974259L (en)
PL (1) PL322200A1 (en)
PT (1) PT815072E (en)
SK (1) SK121797A3 (en)
WO (1) WO1996028415A1 (en)
ZA (1) ZA962142B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19731591C2 (en) * 1997-07-17 1999-09-16 Schering Ag Pharmaceutical compositions containing triiodoaromatics containing perfluoroalkyl groups and their use in tumor therapy and interventional radiology
DE19740403C2 (en) * 1997-09-09 1999-11-11 Schering Ag New contrast media

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
DE2909439A1 (en) * 1979-03-08 1980-09-18 Schering Ag NEW NON-ionic x-ray contrast agents
IT1193211B (en) * 1979-08-09 1988-06-15 Bracco Ind Chimica Spa 2,4,6-TRIIODE-ISOPHTHALIC ACID DERIVATIVES, METHOD FOR THEIR PREPARATION AND CONTRAST MEANS THAT CONTAIN THEM
DE3937118A1 (en) * 1989-11-03 1991-05-08 Schering Ag NON-ionic x-ray contrast agents with high iodine content
US5075502A (en) * 1989-12-13 1991-12-24 Mallinckrodt, Inc. Nonionic x-ray contrast agents, compositions and methods
WO1993010078A1 (en) * 1991-11-18 1993-05-27 Centro Investigacion Justesa Imagen S.A. New non ionic iodized agents for x-ray contrasting method for preparing them and galenical compositions containing them
CA2124559A1 (en) * 1991-12-03 1993-06-10 Mills Thomas Kneller Nonionic x-ray contrast agents, compositions and methods
AU5093993A (en) * 1992-09-02 1994-03-29 Mallinckrodt Medical, Inc. Nonionic X-ray contrast agents compositions and methods

Also Published As

Publication number Publication date
ES2148731T3 (en) 2000-10-16
FI973692A (en) 1997-09-15
FI973692A0 (en) 1997-09-15
EP0815072A1 (en) 1998-01-07
DK0815072T3 (en) 2000-09-04
HUP9800850A2 (en) 1998-07-28
CZ291597A3 (en) 1998-02-18
DE19510864A1 (en) 1996-09-19
SK121797A3 (en) 1998-05-06
KR19980703059A (en) 1998-09-05
MX9706555A (en) 1997-11-29
PL322200A1 (en) 1998-01-19
EP0815072B1 (en) 2000-06-28
AU4718696A (en) 1996-10-02
ATE194138T1 (en) 2000-07-15
ZA962142B (en) 1996-09-26
GR3034472T3 (en) 2000-12-29
PT815072E (en) 2000-10-31
WO1996028415A1 (en) 1996-09-19
JPH11501638A (en) 1999-02-09
CA2215385A1 (en) 1996-09-19
DE59605508D1 (en) 2000-08-03
HUP9800850A3 (en) 1998-08-28
NO974259L (en) 1997-11-14
NO974259D0 (en) 1997-09-15

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