SK118295A3 - Octahydro- or hexahydro-1h-izoindoles and pharmaceutical compositions on their base - Google Patents
Octahydro- or hexahydro-1h-izoindoles and pharmaceutical compositions on their base Download PDFInfo
- Publication number
- SK118295A3 SK118295A3 SK1182-95A SK118295A SK118295A3 SK 118295 A3 SK118295 A3 SK 118295A3 SK 118295 A SK118295 A SK 118295A SK 118295 A3 SK118295 A3 SK 118295A3
- Authority
- SK
- Slovakia
- Prior art keywords
- acid
- octahydro
- mixture
- compound
- hexahydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3857193A | 1993-03-26 | 1993-03-26 | |
| US9996593A | 1993-07-29 | 1993-07-29 | |
| US08/173,586 US5508424A (en) | 1993-03-26 | 1993-12-23 | 4-arylisoindole analgesics |
| PCT/US1994/003329 WO1994022823A1 (en) | 1993-03-26 | 1994-03-28 | 4-arylisoindole analgesics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK118295A3 true SK118295A3 (en) | 1996-06-05 |
Family
ID=27365417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1182-95A SK118295A3 (en) | 1993-03-26 | 1994-03-28 | Octahydro- or hexahydro-1h-izoindoles and pharmaceutical compositions on their base |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5508424A (cs) |
| EP (1) | EP0690842B1 (cs) |
| JP (1) | JP3326180B2 (cs) |
| CN (1) | CN1123546A (cs) |
| AT (1) | ATE174588T1 (cs) |
| AU (1) | AU674746B2 (cs) |
| BG (1) | BG100017A (cs) |
| CA (1) | CA2159071C (cs) |
| CZ (1) | CZ248195A3 (cs) |
| DE (1) | DE69415307T2 (cs) |
| DK (1) | DK0690842T3 (cs) |
| ES (1) | ES2126750T3 (cs) |
| FI (1) | FI954537A (cs) |
| GR (1) | GR3029534T3 (cs) |
| HU (1) | HUT74087A (cs) |
| NO (1) | NO953785L (cs) |
| PL (1) | PL310829A1 (cs) |
| SK (1) | SK118295A3 (cs) |
| WO (1) | WO1994022823A1 (cs) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5543530A (en) * | 1993-12-23 | 1996-08-06 | Ortho Pharmaceutical Corporation | 4-arylisoindole analgesics |
| US5541217A (en) * | 1995-05-17 | 1996-07-30 | Ortho Pharmaceutical Corporation | 4-arylcyclopenta[c]pyrrole analgesics |
| US5602167A (en) * | 1995-05-17 | 1997-02-11 | Ortho Pharmaceutical Corporation | 4-arylcyclohepta[c] pyrrole analgesics |
| AU2001268638A1 (en) * | 2000-06-22 | 2002-01-02 | The Lubrizol Corporation | Acylating agents and dispersants for lubricating oil and fuels |
| US7135484B2 (en) | 2002-08-14 | 2006-11-14 | Abbott Laboratories | Azabicyclic compounds are central nervous system active agents |
| CA2495589A1 (en) * | 2002-08-14 | 2004-02-26 | Abbott Laboratories | Azabicyclic compounds are central nervous system active agents |
| ES2435790T3 (es) | 2004-12-03 | 2013-12-23 | Intervet International B.V. | Piperazinas sustituidas como antagonistas de CB1 |
| EP1973877A2 (en) * | 2006-01-18 | 2008-10-01 | Schering Corporation | Cannibinoid receptor modulators |
| WO2008130616A2 (en) * | 2007-04-19 | 2008-10-30 | Schering Corporation | Diaryl morpholines as cb1 modulators |
| BRPI0814806A2 (pt) * | 2007-06-28 | 2015-02-03 | Intervet Int Bv | Pirazinas substituídas como antagonistas de cb1 |
| CA2694264A1 (en) * | 2007-06-28 | 2009-01-08 | Intervet International B.V. | Substituted piperazines as cb1 antagonists |
| CN104513172B (zh) * | 2013-09-30 | 2018-02-02 | 天士力医药集团股份有限公司 | 含有三氟甲基的酰胺生物碱、制备方法及其药物用途 |
| AU2017296338A1 (en) | 2016-07-14 | 2019-01-03 | Pfizer Inc. | Novel pyrimidine carboxamides as inhibitors of vanin-1 enzyme |
| EP3978497A4 (en) * | 2019-05-30 | 2022-07-13 | Shanghai Institute of Materia Medica, Chinese Academy of Sciences | FUSED CYCLIC COMPOUND, METHOD FOR PREPARING IT AND ITS USE |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4042707A (en) * | 1976-02-19 | 1977-08-16 | E. I. Du Pont De Nemours And Company | 3α-Arylhydroisoindoles |
| US4689329A (en) * | 1986-02-04 | 1987-08-25 | Mcneilab, Inc. | 5-substituted octahydroindolizine analgesics compounds and 7-keto intermediates |
| FR2676443B1 (fr) * | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives de perhydroisoindole et leur preparation. |
| FR2676442B1 (fr) * | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| US5216018A (en) * | 1992-02-14 | 1993-06-01 | Du Pont Merck Pharmaceutical Company | Hydroisoindolines and hydroisoquinolines as psychotropic |
| DE4230804A1 (de) * | 1992-09-15 | 1994-03-17 | Bayer Ag | 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate |
-
1993
- 1993-12-23 US US08/173,586 patent/US5508424A/en not_active Expired - Lifetime
-
1994
- 1994-03-28 AT AT94912324T patent/ATE174588T1/de active
- 1994-03-28 HU HU9502793A patent/HUT74087A/hu unknown
- 1994-03-28 CZ CZ952481A patent/CZ248195A3/cs unknown
- 1994-03-28 DE DE69415307T patent/DE69415307T2/de not_active Expired - Lifetime
- 1994-03-28 JP JP52224794A patent/JP3326180B2/ja not_active Expired - Lifetime
- 1994-03-28 PL PL94310829A patent/PL310829A1/xx unknown
- 1994-03-28 CN CN94192113A patent/CN1123546A/zh active Pending
- 1994-03-28 SK SK1182-95A patent/SK118295A3/sk unknown
- 1994-03-28 WO PCT/US1994/003329 patent/WO1994022823A1/en active IP Right Grant
- 1994-03-28 ES ES94912324T patent/ES2126750T3/es not_active Expired - Lifetime
- 1994-03-28 AU AU64933/94A patent/AU674746B2/en not_active Expired
- 1994-03-28 DK DK94912324T patent/DK0690842T3/da active
- 1994-03-28 CA CA002159071A patent/CA2159071C/en not_active Expired - Lifetime
- 1994-03-28 EP EP94912324A patent/EP0690842B1/en not_active Expired - Lifetime
-
1995
- 1995-09-20 BG BG100017A patent/BG100017A/bg unknown
- 1995-09-25 NO NO953785A patent/NO953785L/no unknown
- 1995-09-25 FI FI954537A patent/FI954537A/fi not_active Application Discontinuation
-
1999
- 1999-03-01 GR GR990400629T patent/GR3029534T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CZ248195A3 (en) | 1996-02-14 |
| DK0690842T3 (da) | 1999-08-23 |
| AU674746B2 (en) | 1997-01-09 |
| PL310829A1 (en) | 1996-01-08 |
| GR3029534T3 (en) | 1999-06-30 |
| AU6493394A (en) | 1994-10-24 |
| ATE174588T1 (de) | 1999-01-15 |
| FI954537A (fi) | 1995-10-27 |
| HU9502793D0 (en) | 1995-11-28 |
| EP0690842B1 (en) | 1998-12-16 |
| US5508424A (en) | 1996-04-16 |
| CA2159071C (en) | 2005-06-28 |
| CN1123546A (zh) | 1996-05-29 |
| ES2126750T3 (es) | 1999-04-01 |
| DE69415307D1 (de) | 1999-01-28 |
| JPH08509212A (ja) | 1996-10-01 |
| JP3326180B2 (ja) | 2002-09-17 |
| FI954537A0 (fi) | 1995-09-25 |
| BG100017A (bg) | 1996-04-30 |
| HUT74087A (en) | 1996-11-28 |
| DE69415307T2 (de) | 1999-06-17 |
| NO953785D0 (no) | 1995-09-25 |
| NO953785L (no) | 1995-09-25 |
| EP0690842A1 (en) | 1996-01-10 |
| WO1994022823A1 (en) | 1994-10-13 |
| CA2159071A1 (en) | 1994-10-13 |
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