SK117599A3 - Dna sequence, a vector containing it, a host cell, isoform of g1 protein, method for producing isoform of g1 protein, pharmaceutical composition containing it and its use - Google Patents

Dna sequence, a vector containing it, a host cell, isoform of g1 protein, method for producing isoform of g1 protein, pharmaceutical composition containing it and its use Download PDF

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Publication number
SK117599A3
SK117599A3 SK1175-99A SK117599A SK117599A3 SK 117599 A3 SK117599 A3 SK 117599A3 SK 117599 A SK117599 A SK 117599A SK 117599 A3 SK117599 A3 SK 117599A3
Authority
SK
Slovakia
Prior art keywords
protein
mort
cells
proteins
fas
Prior art date
Application number
SK1175-99A
Other languages
English (en)
Slovak (sk)
Inventor
David Wallach
Yura Goltsev
Andrei Kovalenko
Eugene Varfolomeev
Vadim Brodianski
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL12036797A external-priority patent/IL120367A0/xx
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of SK117599A3 publication Critical patent/SK117599A3/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472Cysteine endopeptidases (3.4.22)
    • C12N9/6475Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
SK1175-99A 1997-03-03 1998-02-26 Dna sequence, a vector containing it, a host cell, isoform of g1 protein, method for producing isoform of g1 protein, pharmaceutical composition containing it and its use SK117599A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL12036797A IL120367A0 (en) 1997-03-03 1997-03-03 Modulators of the function of FAS receptors and other proteins
IL12075997A IL120759A0 (en) 1997-03-03 1997-05-01 Modulators of the function of fas receptors and other proteins
PCT/IL1998/000098 WO1998039435A1 (en) 1997-03-03 1998-02-26 Cash (caspase homologue) with death effector domain, modulators of the function of fas receptors

Publications (1)

Publication Number Publication Date
SK117599A3 true SK117599A3 (en) 2000-05-16

Family

ID=26323378

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1175-99A SK117599A3 (en) 1997-03-03 1998-02-26 Dna sequence, a vector containing it, a host cell, isoform of g1 protein, method for producing isoform of g1 protein, pharmaceutical composition containing it and its use

Country Status (19)

Country Link
US (1) US7419804B2 (pt)
EP (1) EP0977842A1 (pt)
JP (1) JP2002500508A (pt)
KR (1) KR100544776B1 (pt)
CN (1) CN1148446C (pt)
AU (1) AU740223B2 (pt)
BG (1) BG64799B1 (pt)
BR (1) BR9808173A (pt)
CA (1) CA2281484A1 (pt)
EA (1) EA003269B1 (pt)
EE (1) EE9900384A (pt)
HK (1) HK1024508A1 (pt)
HU (1) HUP0000913A3 (pt)
IL (3) IL120759A0 (pt)
NO (1) NO994250L (pt)
NZ (1) NZ337143A (pt)
PL (1) PL193394B1 (pt)
SK (1) SK117599A3 (pt)
WO (1) WO1998039435A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19713393C2 (de) * 1997-04-01 2002-12-05 Apotech Res & Dev Ltd Flip-Gen und Flip-Protein
DE19713434C1 (de) * 1997-04-01 1998-09-24 Deutsches Krebsforsch Protein zur Inhibierung von Apoptose
WO2000003023A1 (en) * 1998-07-08 2000-01-20 Merck Frosst Canada & Co. Usurpin, a mammalian ded-caspase homologue that precludes caspase-8 recruitment and activation by the cd-95 (fas, apo-1) receptor complex
AU2222000A (en) * 1998-12-31 2000-07-31 St. Jude Children's Research Hospital A tumor suppressor protein involved in death signaling, and diagnostics, therapeutics, and screening based on this protein
US7052834B1 (en) 1998-12-31 2006-05-30 St. Jude Children's Research Hospital Tumor suppressor protein involved in death signaling, and diagnostics, therapeutics, and screening based on this protein
US20020174450A1 (en) * 2000-12-11 2002-11-21 Allen Keith D. Transgenic mice containing cash gene disruptions
CN110988354A (zh) * 2019-11-15 2020-04-10 同济大学 一种分泌蛋白Caspase1在早期心梗诊断试剂中的应用
CN116426678B (zh) * 2023-03-27 2024-03-22 中国热带农业科学院三亚研究院 与番木瓜果肉果糖含量相关的snp分子标记及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL114615A0 (en) 1995-07-16 1995-11-27 Yeda Res & Dev Modulators of the function of fas receptors and other proteins
EP0841399A3 (en) * 1996-11-12 1998-07-08 Smithkline Beecham Corporation Mammalian fin-1 nucleic acid (a caspase) and protein sequences and uses therefor
JP2001511011A (ja) 1997-01-21 2001-08-07 ヒューマン ジノーム サイエンシーズ,インコーポレイテッド 腫瘍壊死因子レセプター−1誘導性アポトーシスおよびcd−95誘導性アポトーシスの新規なインヒビターである、i−flice
US6242569B1 (en) 1997-02-05 2001-06-05 Tularik, Inc. Regulators of apoptosis
DE19713393C2 (de) * 1997-04-01 2002-12-05 Apotech Res & Dev Ltd Flip-Gen und Flip-Protein
US6207458B1 (en) * 1998-05-07 2001-03-27 University Of Washigton/Stowers Insitute For Medical Research Proteins capable of regulating NF-κB JNK and apoptosis pathways and methods of using the same

Also Published As

Publication number Publication date
IL131247A (en) 2007-08-19
KR100544776B1 (ko) 2006-01-23
AU740223B2 (en) 2001-11-01
EE9900384A (et) 2000-04-17
BG64799B1 (bg) 2006-04-28
EP0977842A1 (en) 2000-02-09
CN1148446C (zh) 2004-05-05
EA003269B1 (ru) 2003-02-27
NO994250D0 (no) 1999-09-02
HK1024508A1 (en) 2000-10-13
HUP0000913A2 (hu) 2000-06-28
BR9808173A (pt) 2000-05-16
WO1998039435A1 (en) 1998-09-11
JP2002500508A (ja) 2002-01-08
CA2281484A1 (en) 1998-09-11
EA199900794A1 (ru) 2000-04-24
HUP0000913A3 (en) 2001-11-28
PL335448A1 (en) 2000-04-25
NZ337143A (en) 2001-12-21
US7419804B2 (en) 2008-09-02
IL131247A0 (en) 2001-01-28
CN1249780A (zh) 2000-04-05
BG103693A (en) 2000-05-31
AU6112698A (en) 1998-09-22
KR20000075721A (ko) 2000-12-26
NO994250L (no) 1999-11-02
US20060216788A1 (en) 2006-09-28
IL120759A0 (en) 1997-09-30
PL193394B1 (pl) 2007-02-28

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