IL120759A0 - Modulators of the function of fas receptors and other proteins - Google Patents

Modulators of the function of fas receptors and other proteins

Info

Publication number
IL120759A0
IL120759A0 IL12075997A IL12075997A IL120759A0 IL 120759 A0 IL120759 A0 IL 120759A0 IL 12075997 A IL12075997 A IL 12075997A IL 12075997 A IL12075997 A IL 12075997A IL 120759 A0 IL120759 A0 IL 120759A0
Authority
IL
Israel
Prior art keywords
modulators
proteins
function
fas receptors
fas
Prior art date
Application number
IL12075997A
Other languages
English (en)
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL12036797A external-priority patent/IL120367A0/xx
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL12075997A priority Critical patent/IL120759A0/xx
Publication of IL120759A0 publication Critical patent/IL120759A0/xx
Priority to PL98335448A priority patent/PL193394B1/pl
Priority to CA002281484A priority patent/CA2281484A1/en
Priority to KR1019997007790A priority patent/KR100544776B1/ko
Priority to EP98905598A priority patent/EP0977842A1/en
Priority to EEP199900384A priority patent/EE9900384A/xx
Priority to IL13124798A priority patent/IL131247A0/xx
Priority to HU0000913A priority patent/HUP0000913A3/hu
Priority to BR9808173-0A priority patent/BR9808173A/pt
Priority to NZ337143A priority patent/NZ337143A/en
Priority to SK1175-99A priority patent/SK117599A3/sk
Priority to EA199900794A priority patent/EA003269B1/ru
Priority to CNB988030748A priority patent/CN1148446C/zh
Priority to AU61126/98A priority patent/AU740223B2/en
Priority to JP53833198A priority patent/JP2002500508A/ja
Priority to PCT/IL1998/000098 priority patent/WO1998039435A1/en
Priority to IL131247A priority patent/IL131247A/en
Priority to BG103693A priority patent/BG64799B1/bg
Priority to NO994250A priority patent/NO994250L/no
Priority to HK00103826A priority patent/HK1024508A1/xx
Priority to US10/849,901 priority patent/US20040230039A1/en
Priority to US10/998,582 priority patent/US7407771B2/en
Priority to US11/448,842 priority patent/US7419804B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL12075997A 1997-03-01 1997-05-01 Modulators of the function of fas receptors and other proteins IL120759A0 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
IL12075997A IL120759A0 (en) 1997-03-03 1997-05-01 Modulators of the function of fas receptors and other proteins
JP53833198A JP2002500508A (ja) 1997-03-03 1998-02-26 デスエフェクタードメインを有するｃａｓｈ（カスパーゼホモログ）、ｆａｓレセプター機能モジュレーター
PCT/IL1998/000098 WO1998039435A1 (en) 1997-03-03 1998-02-26 Cash (caspase homologue) with death effector domain, modulators of the function of fas receptors
NZ337143A NZ337143A (en) 1997-03-03 1998-02-26 Caspase homologue with death effector domain for the modulation of MORT-1 alone or in association with G1 proteins is able to enhance FAS-receptor or p55-receptor associated effect on cells
CNB988030748A CN1148446C (zh) 1997-03-03 1998-02-26 与mort-1和mach结合的多肽及其dna序列、生产方法、药物组合物和用途
KR1019997007790A KR100544776B1 (ko) 1997-03-03 1998-02-26 사멸 효과물질 도메인을 가진 ｃａｓｈ 및 ｆａｓ 수용체 기능을 조절하는 조절물질
EP98905598A EP0977842A1 (en) 1997-03-03 1998-02-26 Cash (caspase homologue) with death effector domain, modulators of the function of fas receptors
EEP199900384A EE9900384A (et) 1997-03-03 1998-02-26 Surmaefektori domeeniga CASH (kaspaasi homoloog) molekulid, FAS retseptorite funktsiooni modulaatorid
IL13124798A IL131247A0 (en) 1997-03-03 1998-02-26 Cash protein its preparation and use
HU0000913A HUP0000913A3 (en) 1997-03-03 1998-02-26 Cash (caspase homologue) with death effector domain, modulators of the function of fas receptors
BR9808173-0A BR9808173A (pt) 1997-03-03 1998-02-26 Cash (homólogo de caspase) com domìnio efetor de morte, moduladores da função de receptores de fas
PL98335448A PL193394B1 (pl) 1997-03-03 1998-02-26 Sekwencja DNA, jej zastosowanie, wektor i jego zastosowanie, transformowana komórka, polipeptyd o aktywności białka G1 i sposoby jego wytwarzania, izolowania i identyfikowania, oraz jego zastosowanie, sposoby modulowania działania liganda FAS-R lub TNF in vitro, sposoby przesiewowego badania liganda i sekwencji DNA kodującej ten ligand, sposoby jego identyfikacji wytwarzania oraz izolowania i kompozycja farmaceutyczna
SK1175-99A SK117599A3 (en) 1997-03-03 1998-02-26 Dna sequence, a vector containing it, a host cell, isoform of g1 protein, method for producing isoform of g1 protein, pharmaceutical composition containing it and its use
EA199900794A EA003269B1 (ru) 1997-03-03 1998-02-26 Cash (гомолог каспазы) с "гибель-эффекторным" доменом, модуляторы функций fas-рецепторов
CA002281484A CA2281484A1 (en) 1997-03-03 1998-02-26 Cash (caspase homologue) with death effector domain, modulators of the function of fas receptors
AU61126/98A AU740223B2 (en) 1997-03-03 1998-02-26 CASH (Caspase Homologue) with death effector domain, modulators of the function of FAS receptors
IL131247A IL131247A (en) 1997-03-03 1999-08-04 CASH protein preparation and use
BG103693A BG64799B1 (bg) 1997-03-03 1999-08-26 Саsн (хомолог на каспаза) със смъртоносен ефекторен домен и модулатори на функцията на fаs рецептори
NO994250A NO994250L (no) 1997-03-03 1999-09-02 Cash (Caspase-homolog) med "dödseffektor" domene, modulatorer av funksjonen til FAS-reseptorer
HK00103826A HK1024508A1 (en) 1997-03-03 2000-06-23 Polypeptides binding to mort-1 and mach, its sequence, preparation, composition and use.
US10/849,901 US20040230039A1 (en) 1997-03-01 2004-05-21 Cash (caspase homologue) with death effector domain, modulators of the function of FAS receptors
US10/998,582 US7407771B2 (en) 1997-03-03 2004-11-30 Cash (caspase homologue) with death effector domain, modulators of the function of FAS receptors
US11/448,842 US7419804B2 (en) 1997-03-03 2006-06-08 CASH (Caspase Homologue) with death effector domain, modulators of the function of FAS

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL12036797A IL120367A0 (en) 1997-03-03 1997-03-03 Modulators of the function of FAS receptors and other proteins
IL12075997A IL120759A0 (en) 1997-03-03 1997-05-01 Modulators of the function of fas receptors and other proteins

Publications (1)

Publication Number Publication Date
IL120759A0 true IL120759A0 (en) 1997-09-30

Family

ID=26323378

Family Applications (3)

Application Number Title Priority Date Filing Date
IL12075997A IL120759A0 (en) 1997-03-01 1997-05-01 Modulators of the function of fas receptors and other proteins
IL13124798A IL131247A0 (en) 1997-03-03 1998-02-26 Cash protein its preparation and use
IL131247A IL131247A (en) 1997-03-03 1999-08-04 CASH protein preparation and use

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL13124798A IL131247A0 (en) 1997-03-03 1998-02-26 Cash protein its preparation and use
IL131247A IL131247A (en) 1997-03-03 1999-08-04 CASH protein preparation and use

Country Status (19)

Country Link
US (1) US7419804B2 (xx)
EP (1) EP0977842A1 (xx)
JP (1) JP2002500508A (xx)
KR (1) KR100544776B1 (xx)
CN (1) CN1148446C (xx)
AU (1) AU740223B2 (xx)
BG (1) BG64799B1 (xx)
BR (1) BR9808173A (xx)
CA (1) CA2281484A1 (xx)
EA (1) EA003269B1 (xx)
EE (1) EE9900384A (xx)
HK (1) HK1024508A1 (xx)
HU (1) HUP0000913A3 (xx)
IL (3) IL120759A0 (xx)
NO (1) NO994250L (xx)
NZ (1) NZ337143A (xx)
PL (1) PL193394B1 (xx)
SK (1) SK117599A3 (xx)
WO (1) WO1998039435A1 (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19713393C2 (de) * 1997-04-01 2002-12-05 Apotech Res & Dev Ltd Flip-Gen und Flip-Protein
DE19713434C1 (de) * 1997-04-01 1998-09-24 Deutsches Krebsforsch Protein zur Inhibierung von Apoptose
WO2000003023A1 (en) * 1998-07-08 2000-01-20 Merck Frosst Canada & Co. Usurpin, a mammalian ded-caspase homologue that precludes caspase-8 recruitment and activation by the cd-95 (fas, apo-1) receptor complex
AU2222000A (en) * 1998-12-31 2000-07-31 St. Jude Children's Research Hospital A tumor suppressor protein involved in death signaling, and diagnostics, therapeutics, and screening based on this protein
US7052834B1 (en) 1998-12-31 2006-05-30 St. Jude Children's Research Hospital Tumor suppressor protein involved in death signaling, and diagnostics, therapeutics, and screening based on this protein
US20020174450A1 (en) * 2000-12-11 2002-11-21 Allen Keith D. Transgenic mice containing cash gene disruptions
CN110988354A (zh) * 2019-11-15 2020-04-10 同济大学 一种分泌蛋白Caspase1在早期心梗诊断试剂中的应用
CN116426678B (zh) * 2023-03-27 2024-03-22 中国热带农业科学院三亚研究院 与番木瓜果肉果糖含量相关的snp分子标记及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL114615A0 (en) 1995-07-16 1995-11-27 Yeda Res & Dev Modulators of the function of fas receptors and other proteins
EP0841399A3 (en) * 1996-11-12 1998-07-08 Smithkline Beecham Corporation Mammalian fin-1 nucleic acid (a caspase) and protein sequences and uses therefor
JP2001511011A (ja) 1997-01-21 2001-08-07 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド 腫瘍壊死因子レセプター−１誘導性アポトーシスおよびｃｄ−９５誘導性アポトーシスの新規なインヒビターである、ｉ−ｆｌｉｃｅ
US6242569B1 (en) 1997-02-05 2001-06-05 Tularik, Inc. Regulators of apoptosis
DE19713393C2 (de) * 1997-04-01 2002-12-05 Apotech Res & Dev Ltd Flip-Gen und Flip-Protein
US6207458B1 (en) * 1998-05-07 2001-03-27 University Of Washigton/Stowers Insitute For Medical Research Proteins capable of regulating NF-κB JNK and apoptosis pathways and methods of using the same

Also Published As

Publication number Publication date
IL131247A (en) 2007-08-19
KR100544776B1 (ko) 2006-01-23
SK117599A3 (en) 2000-05-16
AU740223B2 (en) 2001-11-01
EE9900384A (et) 2000-04-17
BG64799B1 (bg) 2006-04-28
EP0977842A1 (en) 2000-02-09
CN1148446C (zh) 2004-05-05
EA003269B1 (ru) 2003-02-27
NO994250D0 (no) 1999-09-02
HK1024508A1 (en) 2000-10-13
HUP0000913A2 (hu) 2000-06-28
BR9808173A (pt) 2000-05-16
WO1998039435A1 (en) 1998-09-11
JP2002500508A (ja) 2002-01-08
CA2281484A1 (en) 1998-09-11
EA199900794A1 (ru) 2000-04-24
HUP0000913A3 (en) 2001-11-28
PL335448A1 (en) 2000-04-25
NZ337143A (en) 2001-12-21
US7419804B2 (en) 2008-09-02
IL131247A0 (en) 2001-01-28
CN1249780A (zh) 2000-04-05
BG103693A (en) 2000-05-31
AU6112698A (en) 1998-09-22
KR20000075721A (ko) 2000-12-26
NO994250L (no) 1999-11-02
US20060216788A1 (en) 2006-09-28
PL193394B1 (pl) 2007-02-28

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