SI9600185A - Novel crystal form of anhydrous 7-((1alpha, 5alpha,6alpha)-6-amino-3-azabicyclo (3.1.0.) hex-3-il) -6-fluoro-1- (2,4 difluorophenyl) -1,4-dihydro-4-oxo-1,8 naphthyridine -3-carboxylic acids, methanesulfonic acid salt - Google Patents

Novel crystal form of anhydrous 7-((1alpha, 5alpha,6alpha)-6-amino-3-azabicyclo (3.1.0.) hex-3-il) -6-fluoro-1- (2,4 difluorophenyl) -1,4-dihydro-4-oxo-1,8 naphthyridine -3-carboxylic acids, methanesulfonic acid salt Download PDF

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Publication number
SI9600185A
SI9600185A SI9600185A SI9600185A SI9600185A SI 9600185 A SI9600185 A SI 9600185A SI 9600185 A SI9600185 A SI 9600185A SI 9600185 A SI9600185 A SI 9600185A SI 9600185 A SI9600185 A SI 9600185A
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SI
Slovenia
Prior art keywords
fluoro
difluorophenyl
dihydro
oxo
amino
Prior art date
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SI9600185A
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English (en)
Slovenian (sl)
Inventor
A Lynne Handanyan
L Robert Hendrickson
J Phillip Johnson
A Thomas Morris
Timothy Norris
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Pfizer
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Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SI9600185A publication Critical patent/SI9600185A/sl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SI9600185A 1995-06-06 1996-06-06 Novel crystal form of anhydrous 7-((1alpha, 5alpha,6alpha)-6-amino-3-azabicyclo (3.1.0.) hex-3-il) -6-fluoro-1- (2,4 difluorophenyl) -1,4-dihydro-4-oxo-1,8 naphthyridine -3-carboxylic acids, methanesulfonic acid salt SI9600185A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1995/007211 WO1996039406A1 (en) 1995-06-06 1995-06-06 NOVEL CRYSTAL FORM OF ANHYDROUS 7-([1α, 5α, 6α]-6-AMINO-3-AZABICYCLO[3.1.0]HEX-3-YL)-6-FLUORO-1-(2,4-DIFLUOROPHENYL)-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID, METHANESULFONIC ACID SALT

Publications (1)

Publication Number Publication Date
SI9600185A true SI9600185A (en) 1997-04-30

Family

ID=39431076

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9600185A SI9600185A (en) 1995-06-06 1996-06-06 Novel crystal form of anhydrous 7-((1alpha, 5alpha,6alpha)-6-amino-3-azabicyclo (3.1.0.) hex-3-il) -6-fluoro-1- (2,4 difluorophenyl) -1,4-dihydro-4-oxo-1,8 naphthyridine -3-carboxylic acids, methanesulfonic acid salt

Country Status (38)

Country Link
US (1) US5763454A (cs)
EP (1) EP0789697B1 (cs)
JP (1) JP3145715B2 (cs)
KR (1) KR100191989B1 (cs)
CN (1) CN1055474C (cs)
AR (1) AR002753A1 (cs)
AU (1) AU703634B2 (cs)
BG (1) BG62443B1 (cs)
BR (1) BR9602630A (cs)
CA (1) CA2223404C (cs)
CZ (1) CZ285878B6 (cs)
DE (1) DE69503066T2 (cs)
DK (1) DK0789697T3 (cs)
DZ (1) DZ2046A1 (cs)
ES (1) ES2117426T3 (cs)
FI (1) FI974441A0 (cs)
HR (1) HRP960267B1 (cs)
HU (1) HUP9601540A3 (cs)
IL (1) IL118488A (cs)
IS (1) IS4351A (cs)
LV (1) LV11619B (cs)
MA (1) MA23892A1 (cs)
NO (1) NO305599B1 (cs)
NZ (1) NZ286735A (cs)
OA (1) OA10293A (cs)
PE (1) PE38097A1 (cs)
PL (1) PL314604A1 (cs)
RU (1) RU2125571C1 (cs)
SG (1) SG54339A1 (cs)
SI (1) SI9600185A (cs)
SK (1) SK280535B6 (cs)
TN (1) TNSN96084A1 (cs)
TW (2) TW403751B (cs)
UA (1) UA44718C2 (cs)
UY (1) UY25459A1 (cs)
WO (1) WO1996039406A1 (cs)
YU (1) YU34596A (cs)
ZA (1) ZA964647B (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA24500A1 (fr) 1997-03-21 1998-10-01 Lg Life Sciences Ltd Derive du sel d'acide carboxylique de naphthyridine .
US20020032216A1 (en) 1997-03-21 2002-03-14 Lg Chemical Ltd. Salt of naphthyridine carboxylic acid derivative
HN1998000106A (es) 1997-08-01 1999-01-08 Pfizer Prod Inc Composiciones parenterales de alatroflaxacino
DE19800214A1 (de) * 1998-01-06 1999-07-15 Knoll Ag Verfahren zur Herstellung von Doxazosin-Mcsylat in einer als Form A bezeichneten Kristallmodifikation und ein Zwischenprodukt dafür
US7019142B2 (en) * 1998-01-16 2006-03-28 Pfizer Inc. Process for preparing naphthyridones and intermediates
GB9818258D0 (en) * 1998-08-21 1998-10-14 Pfizer Ltd Antifungal compositions
HN1999000141A (es) * 1998-09-03 2000-06-19 Pfizer Prod Inc Procedimiento para preparar sales de trovafloxacina de adicion de acidos.
GB9820405D0 (en) * 1998-09-18 1998-11-11 Smithkline Beecham Plc Process
ES2164520B1 (es) * 1999-03-16 2003-04-01 Medichem Sa "procedimiento de obtencion del polimorfo a del mesilato de doxazosina"
US6239141B1 (en) 1999-06-04 2001-05-29 Pfizer Inc. Trovafloxacin oral suspensions
GB9920919D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
GB9920917D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
US6573382B2 (en) 2001-06-29 2003-06-03 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6388080B1 (en) 2001-06-29 2002-05-14 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6657061B2 (en) 2001-06-29 2003-12-02 Grayson Walker Stowell Polymorphic forms of 6-[4-1(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6660864B2 (en) 2001-06-29 2003-12-09 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6531603B1 (en) 2001-06-29 2003-03-11 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6596871B2 (en) 2001-06-29 2003-07-22 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1h-tetraol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
KR100517638B1 (ko) 2002-04-08 2005-09-28 주식회사 엘지생명과학 게미플록사신 산염의 새로운 제조방법
CN102512364A (zh) * 2011-12-30 2012-06-27 天津市嵩锐医药科技有限公司 一种供注射用的甲磺酸阿拉曲伐沙星药物组合物
WO2014109376A1 (ja) * 2013-01-11 2014-07-17 参天製薬株式会社 中栓とその中栓を備えた液体収容容器、及びノズルの先端構造とその構造を備えた液体収容容器

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2049777C1 (ru) * 1989-08-16 1995-12-10 Пфайзер Инк. Азабицикло-хинолон-карбоновые кислоты или их фармацевтически приемлемые кислотно-аддитивные соли и промежуточные продукты для их получения
US5164402A (en) * 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids
CZ286896B6 (en) * 1994-01-18 2000-07-12 Pfizer Process for preparing pharmaceutically acceptable salts of naphthyridone carboxylic acid and intermediates for this preparation
GB2289674A (en) * 1994-05-23 1995-11-29 Pfizer Antibacterial naphthyridine

Also Published As

Publication number Publication date
DE69503066T2 (de) 1998-10-15
LV11619B (en) 1997-04-20
ZA964647B (en) 1997-10-22
SK280535B6 (sk) 2000-03-13
CA2223404A1 (en) 1996-12-12
HRP960267A2 (en) 1997-08-31
BR9602630A (pt) 1998-09-08
KR100191989B1 (ko) 1999-06-15
IL118488A0 (en) 1996-09-12
FI974441A7 (fi) 1997-12-05
DZ2046A1 (fr) 2002-10-22
FI974441L (fi) 1997-12-05
PE38097A1 (es) 1997-10-10
JP3145715B2 (ja) 2001-03-12
RU2125571C1 (ru) 1999-01-27
NO962321D0 (no) 1996-06-05
KR970001352A (ko) 1997-01-24
HUP9601540A3 (en) 1997-05-28
DK0789697T3 (da) 1998-10-19
CA2223404C (en) 2001-01-16
OA10293A (en) 1997-09-19
US5763454A (en) 1998-06-09
NZ286735A (en) 1998-01-26
TNSN96084A1 (fr) 2005-03-15
TW580389B (en) 2004-03-21
AU703634B2 (en) 1999-03-25
LV11619A (lv) 1996-12-20
YU34596A (sh) 1999-03-04
IL118488A (en) 1999-01-26
AR002753A1 (es) 1998-04-29
HRP960267B1 (en) 2000-06-30
BG100639A (bg) 1997-02-28
PL314604A1 (en) 1996-12-09
FI974441A0 (fi) 1997-12-05
CZ162596A3 (cs) 1998-09-16
HUP9601540A2 (en) 1997-02-28
SG54339A1 (en) 1998-11-16
UA44718C2 (uk) 2002-03-15
NO305599B1 (no) 1999-06-28
TW403751B (en) 2000-09-01
EP0789697B1 (en) 1998-06-17
UY25459A1 (es) 1999-11-17
EP0789697A1 (en) 1997-08-20
CN1148596A (zh) 1997-04-30
BG62443B1 (bg) 1999-11-30
WO1996039406A1 (en) 1996-12-12
NO962321L (no) 1996-12-09
DE69503066D1 (de) 1998-07-23
JPH10506650A (ja) 1998-06-30
IS4351A (is) 1996-12-07
HU9601540D0 (en) 1996-07-29
CN1055474C (zh) 2000-08-16
AU5474996A (en) 1996-12-19
ES2117426T3 (es) 1998-08-01
CZ285878B6 (cs) 1999-11-17
MA23892A1 (fr) 1996-12-31
MX9709873A (es) 1998-03-31
SK71996A3 (en) 1997-03-05

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