SI4194548T1 - GENERACIJA FUNKCIONALNIH CELIC BETA, IZPELJANIH IZ HUMANIH PLURIPOTENTNIH MATIČNIH CELIC, KlKAŽEJO OD GLUKOZE ODVISNO MITOHONDRIJSKO DIHANJE IN DVOFAZNI ODZIV NA IZLOČANJE INSULINA - Google Patents

GENERACIJA FUNKCIONALNIH CELIC BETA, IZPELJANIH IZ HUMANIH PLURIPOTENTNIH MATIČNIH CELIC, KlKAŽEJO OD GLUKOZE ODVISNO MITOHONDRIJSKO DIHANJE IN DVOFAZNI ODZIV NA IZLOČANJE INSULINA

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Publication number
SI4194548T1
SI4194548T1 SI201731644T SI201731644T SI4194548T1 SI 4194548 T1 SI4194548 T1 SI 4194548T1 SI 201731644 T SI201731644 T SI 201731644T SI 201731644 T SI201731644 T SI 201731644T SI 4194548 T1 SI4194548 T1 SI 4194548T1
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SI
Slovenia
Prior art keywords
mitochondral
respiration
dependent
generation
pluripotent stem
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Application number
SI201731644T
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English (en)
Slovenian (sl)
Inventor
Sebastian Rieck
Alireza Rezania
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Janssen Biotech, Inc.
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Publication date
Application filed by Janssen Biotech, Inc. filed Critical Janssen Biotech, Inc.
Publication of SI4194548T1 publication Critical patent/SI4194548T1/sl

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • A61K35/39Pancreas; Islets of Langerhans
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SI201731644T 2016-06-21 2017-06-14 GENERACIJA FUNKCIONALNIH CELIC BETA, IZPELJANIH IZ HUMANIH PLURIPOTENTNIH MATIČNIH CELIC, KlKAŽEJO OD GLUKOZE ODVISNO MITOHONDRIJSKO DIHANJE IN DVOFAZNI ODZIV NA IZLOČANJE INSULINA SI4194548T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662352968P 2016-06-21 2016-06-21
EP22213072.6A EP4194548B1 (en) 2016-06-21 2017-06-14 Generation of human pluripotent stem cell derived functional beta cells showing a glucose-dependent mitochondrial respiration and two-phase insulin secretion response

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SI4194548T1 true SI4194548T1 (sl) 2026-03-31

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US (3) US10633635B2 (https=)
EP (3) EP3472303B1 (https=)
JP (4) JP7044726B2 (https=)
KR (5) KR102489946B1 (https=)
CN (2) CN116286663A (https=)
AR (1) AR108847A1 (https=)
AU (3) AU2017282638C1 (https=)
CA (1) CA3027879A1 (https=)
DK (2) DK3472303T3 (https=)
ES (2) ES2939233T3 (https=)
FI (1) FI4194548T3 (https=)
HR (1) HRP20260022T1 (https=)
LT (1) LT4194548T (https=)
MA (2) MA71715B1 (https=)
MD (1) MD4194548T2 (https=)
PL (1) PL4194548T3 (https=)
PT (1) PT4194548T (https=)
RS (1) RS67611B1 (https=)
RU (1) RU2752499C2 (https=)
SG (1) SG11201810550WA (https=)
SI (1) SI4194548T1 (https=)
SM (1) SMT202600006T1 (https=)
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KR102738995B1 (ko) * 2017-09-11 2024-12-06 노보 노르디스크 에이/에스 시험관 내 줄기 세포로부터 유래된 nkx6.1 및 c-펩티드 공발현 세포의 농축
EP3710021A4 (en) 2017-11-15 2021-08-11 Semma Therapeutics, Inc. ISLAND CELL MANUFACTURING COMPOSITIONS AND METHOD OF USE
EP3758719A4 (en) * 2018-03-02 2021-12-08 Vertex Pharmaceuticals Inc. METHODS FOR IMPROVING THE DIFFERENTIATION OF STEM CELLS INTO BETA CELLS
WO2019208788A1 (ja) * 2018-04-27 2019-10-31 株式会社カネカ 膵臓β細胞の製造方法
JP2021522819A (ja) * 2018-05-07 2021-09-02 プレジデント アンド フェローズ オブ ハーバード カレッジ インビトロベータ細胞分化に関連する細胞集団および遺伝子発現
US12421499B2 (en) 2018-05-11 2025-09-23 Cornell University Method of differentiation of human pluripotent stem cells to monohormonal cells
WO2020033879A1 (en) * 2018-08-10 2020-02-13 Semma Therapeutics, Inc. Stem cell derived islet differentiation
US12378572B2 (en) 2018-09-07 2025-08-05 Crispr Therapeutics Ag Universal donor cells
CA3139292C (en) 2019-05-31 2025-06-10 Viacyte, Inc. CELL ENCAPSULATION DEVICES WITH REGULATED OXYGEN DIFFUSION DISTANCES
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