MD4194548T2 - Generarea de celule beta funcționale derivate din celule stem pluripotente umane care posedă respirație mitocondrială dependentă - de glucoză și răspuns la secreția de insulină în două faze - Google Patents

Generarea de celule beta funcționale derivate din celule stem pluripotente umane care posedă respirație mitocondrială dependentă - de glucoză și răspuns la secreția de insulină în două faze

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Publication number
MD4194548T2
MD4194548T2 MDE20240068T MDE20240068T MD4194548T2 MD 4194548 T2 MD4194548 T2 MD 4194548T2 MD E20240068 T MDE20240068 T MD E20240068T MD E20240068 T MDE20240068 T MD E20240068T MD 4194548 T2 MD4194548 T2 MD 4194548T2
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MD
Moldova
Prior art keywords
cells
inhibitor
medium
stage
glucose
Prior art date
Application number
MDE20240068T
Other languages
English (en)
Romanian (ro)
Inventor
Sebastian Rieck
Alireza Rezania
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of MD4194548T2 publication Critical patent/MD4194548T2/ro

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MDE20240068T 2016-06-21 2017-06-14 Generarea de celule beta funcționale derivate din celule stem pluripotente umane care posedă respirație mitocondrială dependentă - de glucoză și răspuns la secreția de insulină în două faze MD4194548T2 (ro)

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US201662352968P 2016-06-21 2016-06-21

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MD4194548T2 true MD4194548T2 (ro) 2026-02-28

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MDE20240068T MD4194548T2 (ro) 2016-06-21 2017-06-14 Generarea de celule beta funcționale derivate din celule stem pluripotente umane care posedă respirație mitocondrială dependentă - de glucoză și răspuns la secreția de insulină în două faze

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US (3) US10633635B2 (https=)
EP (3) EP3472303B1 (https=)
JP (4) JP7044726B2 (https=)
KR (5) KR102489946B1 (https=)
CN (2) CN116286663A (https=)
AR (1) AR108847A1 (https=)
AU (3) AU2017282638C1 (https=)
CA (1) CA3027879A1 (https=)
DK (2) DK3472303T3 (https=)
ES (2) ES2939233T3 (https=)
FI (1) FI4194548T3 (https=)
HR (1) HRP20260022T1 (https=)
LT (1) LT4194548T (https=)
MA (2) MA71715B1 (https=)
MD (1) MD4194548T2 (https=)
PL (1) PL4194548T3 (https=)
PT (1) PT4194548T (https=)
RS (1) RS67611B1 (https=)
RU (1) RU2752499C2 (https=)
SG (1) SG11201810550WA (https=)
SI (1) SI4194548T1 (https=)
SM (1) SMT202600006T1 (https=)
TW (1) TW201809266A (https=)
WO (1) WO2017222879A1 (https=)

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EP3710021A4 (en) 2017-11-15 2021-08-11 Semma Therapeutics, Inc. ISLAND CELL MANUFACTURING COMPOSITIONS AND METHOD OF USE
EP3758719A4 (en) * 2018-03-02 2021-12-08 Vertex Pharmaceuticals Inc. METHODS FOR IMPROVING THE DIFFERENTIATION OF STEM CELLS INTO BETA CELLS
WO2019208788A1 (ja) * 2018-04-27 2019-10-31 株式会社カネカ 膵臓β細胞の製造方法
JP2021522819A (ja) * 2018-05-07 2021-09-02 プレジデント アンド フェローズ オブ ハーバード カレッジ インビトロベータ細胞分化に関連する細胞集団および遺伝子発現
US12421499B2 (en) 2018-05-11 2025-09-23 Cornell University Method of differentiation of human pluripotent stem cells to monohormonal cells
WO2020033879A1 (en) * 2018-08-10 2020-02-13 Semma Therapeutics, Inc. Stem cell derived islet differentiation
US12378572B2 (en) 2018-09-07 2025-08-05 Crispr Therapeutics Ag Universal donor cells
CA3139292C (en) 2019-05-31 2025-06-10 Viacyte, Inc. CELL ENCAPSULATION DEVICES WITH REGULATED OXYGEN DIFFUSION DISTANCES
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