RU2752499C2 - Генерация функциональных бета-клеток, полученных из человеческой плюрипотентной стволовой клетки, демонстрирующих реакцию в виде глюкозозависимого митохондриального дыхания и двухфазной секреции инсулина - Google Patents

Генерация функциональных бета-клеток, полученных из человеческой плюрипотентной стволовой клетки, демонстрирующих реакцию в виде глюкозозависимого митохондриального дыхания и двухфазной секреции инсулина Download PDF

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RU2752499C2
RU2752499C2 RU2019101200A RU2019101200A RU2752499C2 RU 2752499 C2 RU2752499 C2 RU 2752499C2 RU 2019101200 A RU2019101200 A RU 2019101200A RU 2019101200 A RU2019101200 A RU 2019101200A RU 2752499 C2 RU2752499 C2 RU 2752499C2
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cells
medium
inhibitor
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cell
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Себастьян РИК
Алиреза РЕЗАНИА
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Янссен Байотек, Инк.
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RU2019101200A 2016-06-21 2017-06-14 Генерация функциональных бета-клеток, полученных из человеческой плюрипотентной стволовой клетки, демонстрирующих реакцию в виде глюкозозависимого митохондриального дыхания и двухфазной секреции инсулина RU2752499C2 (ru)

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US201662352968P 2016-06-21 2016-06-21
US62/352,968 2016-06-21
PCT/US2017/037373 WO2017222879A1 (en) 2016-06-21 2017-06-14 Generation of human pluripotent stem cell derived functional beta cells showing a glucose-dependent mitochondrial respiration and two-phase insulin secretion response

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RU2019101200A RU2019101200A (ru) 2020-07-21
RU2019101200A3 RU2019101200A3 (https=) 2021-01-18
RU2752499C2 true RU2752499C2 (ru) 2021-07-28

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CN111565707A (zh) 2017-06-14 2020-08-21 森玛治疗公司 用于递送治疗物的装置和方法
AU2018330499B2 (en) * 2017-09-11 2025-01-30 Novo Nordisk A/S Enrichment of NKX6.1 and C-peptide co-expressing cells derived in vitro from stem cells
KR20250048146A (ko) * 2017-11-15 2025-04-07 셈마 테라퓨틱스, 인크. 섬세포 제조 조성물 및 사용 방법
CN112074281A (zh) * 2018-03-02 2020-12-11 沃泰克斯药物股份有限公司 增强干细胞向β细胞分化的方法
JP7311116B2 (ja) * 2018-04-27 2023-07-19 株式会社カネカ 膵臓β細胞の製造方法
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